"Tight Junctions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell-cell junctions that seal adjacent epithelial cells together, preventing the passage of most dissolved molecules from one side of the epithelial sheet to the other. (Alberts et al., Molecular Biology of the Cell, 2nd ed, p22)
| Descriptor ID |
D019108
|
| MeSH Number(s) |
A11.284.149.165.420.820
|
| Concept/Terms |
Tight Junctions- Tight Junctions
- Junction, Tight
- Junctions, Tight
- Tight Junction
- Zonula Occludens
- Occluden, Zonula
- Occludens, Zonula
- Zonula Occluden
- Occluding Junctions
- Junction, Occluding
- Junctions, Occluding
- Occluding Junction
|
Below are MeSH descriptors whose meaning is more general than "Tight Junctions".
Below are MeSH descriptors whose meaning is more specific than "Tight Junctions".
This graph shows the total number of publications written about "Tight Junctions" by people in this website by year, and whether "Tight Junctions" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1999 | 0 | 1 | 1 |
| 2003 | 0 | 3 | 3 |
| 2004 | 1 | 1 | 2 |
| 2005 | 1 | 2 | 3 |
| 2007 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 1 | 2 |
| 2014 | 2 | 0 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 3 | 3 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 3 | 3 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tight Junctions" by people in Profiles.
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HDAC3 promotes Sertoli cell maturation and maintains the blood-testis barrier dynamics. FASEB J. 2024 03 15; 38(5):e23526.
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Cigarette smoke and decreased oxygen tension inhibit pulmonary claudin-6 expression. Exp Lung Res. 2016 Oct - Dec; 42(8-10):440-452.
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Haemocytes control stem cell activity in the Drosophila intestine. Nat Cell Biol. 2015 Jun; 17(6):736-48.
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Bile acids permeabilize the blood brain barrier after bile duct ligation in rats via Rac1-dependent mechanisms. Dig Liver Dis. 2014 Jun; 46(6):527-34.
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Early lead exposure increases the leakage of the blood-cerebrospinal fluid barrier, in vitro. Hum Exp Toxicol. 2007 Mar; 26(3):159-67.
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A differentiation-dependent splice variant of myosin light chain kinase, MLCK1, regulates epithelial tight junction permeability. J Biol Chem. 2004 Dec 31; 279(53):55506-13.
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Identification of a novel protein, LYRIC, localized to tight junctions of polarized epithelial cells. Exp Cell Res. 2004 Oct 15; 300(1):134-48.
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An intravital microscopy study of radiation-induced changes in permeability and leukocyte-endothelial cell interactions in the microvessels of the rat pia mater and cremaster muscle. Brain Res Brain Res Protoc. 2004 Apr; 13(1):1-10.
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Radiation-induced permeability and leukocyte adhesion in the rat blood-brain barrier: modulation with anti-ICAM-1 antibodies. Brain Res. 2003 Apr 18; 969(1-2):59-69.
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Response of wild-type mutants of Vibrio cholerae O1 possessing different combinations of virulence genes in the ligated rabbit ileal loop and in Ussing chambers: evidence for the presence of additional secretogen. J Med Microbiol. 1999 Jan; 48(1):51-57.