"Desmosomes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A type of junction that attaches one cell to its neighbor. One of a number of differentiated regions which occur, for example, where the cytoplasmic membranes of adjacent epithelial cells are closely apposed. It consists of a circular region of each membrane together with associated intracellular microfilaments and an intercellular material which may include, for example, mucopolysaccharides. (From Glick, Glossary of Biochemistry and Molecular Biology, 1990; Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)
| Descriptor ID |
D003896
|
| MeSH Number(s) |
A11.284.149.165.420.297
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Desmosomes".
Below are MeSH descriptors whose meaning is more specific than "Desmosomes".
This graph shows the total number of publications written about "Desmosomes" by people in this website by year, and whether "Desmosomes" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 |
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 2 | 3 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 3 | 3 |
| 2014 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Desmosomes" by people in Profiles.
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Plakophilin 1 in carcinogenesis. Mol Carcinog. 2024 Oct; 63(10):1855-1865.
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Meeting report - Desmosome dysfunction and disease: Alpine desmosome disease meeting. J Cell Sci. 2023 01 01; 136(1).
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Knock Down of Plakophillin 2 Dysregulates Adhesion Pathway through Upregulation of miR200b and Alters the Mechanical Properties in Cardiac Cells. Cells. 2019 12 14; 8(12).
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A Human Stem Cell-Based System to Study?the?Role of TP63 Mutations in Ectodermal Dysplasias. J Invest Dermatol. 2018 07; 138(7):1662-1665.
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Plakophilin3 increases desmosome assembly, size and stability by increasing expression of desmocollin2. Biochem Biophys Res Commun. 2018 01 01; 495(1):768-774.
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Cardiac Fibro-Adipocyte Progenitors Express Desmosome Proteins and Preferentially Differentiate to Adipocytes Upon Deletion of the Desmoplakin Gene. Circ Res. 2016 06 24; 119(1):41-54.
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14-3-3?-Mediated transport of plakoglobin to the cell border is required for the initiation of desmosome assembly in vitro and in vivo. J Cell Sci. 2014 May 15; 127(Pt 10):2174-88.
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On the diagnostic utility of junction plakoglobin in arrhythmogenic right ventricular cardiomyopathy. Cardiovasc Pathol. 2013 Sep-Oct; 22(5):309-11.
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Plakophilin3 loss leads to an increase in PRL3 levels promoting K8 dephosphorylation, which is required for transformation and metastasis. PLoS One. 2012; 7(6):e38561.
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Thymomas with prominent signet ring cell-like features: a clinicopathologic and immunohistochemical study of 10 cases. Hum Pathol. 2012 Nov; 43(11):1881-6.