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SAMUEL WU

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Ophthalmology
Address6501 Fannin St
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Neuroscience
    DivisionNeuroscience


    Collapse Research 
    Collapse research activities and funding
    R01EY033492     (WU, SAMUEL M)Mar 1, 2022 - Feb 28, 2027
    NIH
    Multi-Cellular Analysis of the Retinal Network
    Role: Principal Investigator
    R01EY026930     (CHEN, CHING-KANG JASON)Sep 30, 2017 - Aug 31, 2021
    NIH
    Mechanisms, functions and utility of RGC oscillation in retinal deafferentation mouse models
    Role: Co-Principal Investigator
    R01EY019908     (WU, SAMUEL M)Jan 1, 2010 - Nov 30, 2020
    NIH
    Rod and cone signaling pathways in mammalian retina
    Role: Principal Investigator
    R01EY004446     (WU, SAMUEL M)Feb 1, 1982 - Sep 29, 2016
    NIH
    PHYSIOLOGY AND PHARMACOLOGY OF SYNAPSES IN THE RETINA
    Role: Principal Investigator
    P30EY002520     (WU, SAMUEL M)Jul 1, 1979 - Jun 30, 2025
    NIH
    P30 - Core Grant for Vision Research
    Role: Principal Investigator
    T32EY007001     (WU, SAMUEL M)Jul 1, 1975 - Jul 31, 2028
    NIH
    Research Training in Visual Sciences
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Chen CA, Wang W, Pedersen SE, Raman A, Seymour ML, Ruiz FR, Xia A, van der Heijden ME, Wang L, Yin J, Lopez J, Rech ME, Lewis RA, Wu SM, Liu Z, Pereira FA, Pautler RG, Zoghbi HY, Schaaf CP. Nr2f1 heterozygous knockout mice recapitulate neurological phenotypes of Bosch-Boonstra-Schaaf optic atrophy syndrome and show impaired hippocampal synaptic plasticity. Hum Mol Genet. 2020 03 27; 29(5):705-715. PMID: 31600777; PMCID: PMC7104670.
      Citations: 9     Fields:    Translation:Animals
    2. Lotfi P, Tse DY, Di Ronza A, Seymour ML, Martano G, Cooper JD, Pereira FA, Passafaro M, Wu SM, Sardiello M. Trehalose reduces retinal degeneration, neuroinflammation and storage burden caused by a lysosomal hydrolase deficiency. Autophagy. 2018; 14(8):1419-1434. PMID: 29916295; PMCID: PMC6103706.
      Citations: 38     Fields:    Translation:AnimalsCells
    3. Palmieri M, Pal R, Nelvagal HR, Lotfi P, Stinnett GR, Seymour ML, Chaudhury A, Bajaj L, Bondar VV, Bremner L, Saleem U, Tse DY, Sanagasetti D, Wu SM, Neilson JR, Pereira FA, Pautler RG, Rodney GG, Cooper JD, Sardiello M. mTORC1-independent TFEB activation via Akt inhibition promotes cellular clearance in neurodegenerative storage diseases. Nat Commun. 2017 02 06; 8:14338. PMID: 28165011; PMCID: PMC5303831.
      Citations: 160     Fields:    Translation:HumansAnimalsCells
    4. Eblimit A, Nguyen TM, Chen Y, Esteve-Rudd J, Zhong H, Letteboer S, Van Reeuwijk J, Simons DL, Ding Q, Wu KM, Li Y, Van Beersum S, Moayedi Y, Xu H, Pickard P, Wang K, Gan L, Wu SM, Williams DS, Mardon G, Roepman R, Chen R. Spata7 is a retinal ciliopathy gene critical for correct RPGRIP1 localization and protein trafficking in the retina. Hum Mol Genet. 2015 Mar 15; 24(6):1584-601. PMID: 25398945; PMCID: PMC4351378.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    5. Ressler SJ, Dang TD, Wu SM, Tse DY, Gilbert BE, Vyakarnam A, Yang F, Schauer IG, Barron DA, Rowley DR. WFDC1 is a key modulator of inflammatory and wound repair responses. Am J Pathol. 2014 Nov; 184(11):2951-64. PMID: 25219356; PMCID: PMC4215025.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    6. Price BA, Sandoval IM, Chan F, Simons DL, Wu SM, Wensel TG, Wilson JH. Mislocalization and degradation of human P23H-rhodopsin-GFP in a knockin mouse model of retinitis pigmentosa. Invest Ophthalmol Vis Sci. 2011 Dec 28; 52(13):9728-36. PMID: 22110080; PMCID: PMC3341127.
      Citations: 38     Fields:    Translation:AnimalsCells
    7. Abd-El-Barr MM, Albini TA, Carvounis PE, He F, Manzano RP, Chevez-Barrios P, Wensel TG, Wu SM, Holz ER. Safety and pharmokinetics of triamcinolone hexacetonide in rabbit eyes. J Ocul Pharmacol Ther. 2008 Apr; 24(2):197-205. PMID: 18355133.
      Citations: 1     Fields:    Translation:Animals
    8. Ji J, Chang P, Pennesi ME, Yang Z, Zhang J, Li D, Wu SM, Gross RL. Effects of elevated intraocular pressure on mouse retinal ganglion cells. Vision Res. 2005 Jan; 45(2):169-79. PMID: 15581918.
      Citations: 45     Fields:    Translation:AnimalsCells
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