"DNA, Superhelical" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Circular duplex DNA isolated from viruses, bacteria and mitochondria in supercoiled or supertwisted form. This superhelical DNA is endowed with free energy. During transcription, the magnitude of RNA initiation is proportional to the DNA superhelicity.
| Descriptor ID |
D004278
|
| MeSH Number(s) |
D13.444.308.283.250 G02.111.570.820.486.212.250 G05.360.580.156.250
|
| Concept/Terms |
DNA, Superhelical- DNA, Superhelical
- Superhelical DNA
- DNA, Supertwisted
- Supertwisted DNA
- DNA, Supercoiled
- Supercoiled DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA, Superhelical".
Below are MeSH descriptors whose meaning is more specific than "DNA, Superhelical".
This graph shows the total number of publications written about "DNA, Superhelical" by people in this website by year, and whether "DNA, Superhelical" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 1 | 1 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
| 2023 | 2 | 0 | 2 |
| 2024 | 2 | 1 | 3 |
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Below are the most recent publications written about "DNA, Superhelical" by people in Profiles.
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RNA interacts with topoisomerase I to adjust DNA topology. Mol Cell. 2024 Sep 05; 84(17):3192-3208.e11.
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Structural basis of DNA crossover capture by Escherichia coli DNA gyrase. Science. 2024 04 12; 384(6692):227-232.
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In Vivo Genomic Supercoiling Mapping Using Psora-seq. Methods Mol Biol. 2024; 2819:147-156.
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Suitability of double-stranded DNA as a molecular standard for the validation of analytical ultracentrifugation instruments. Eur Biophys J. 2023 Jul; 52(4-5):267-280.
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DNA supercoiling-induced shapes alter minicircle hydrodynamic properties. Nucleic Acids Res. 2023 05 08; 51(8):4027-4042.
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Psoralen mapping reveals a bacterial genome supercoiling landscape dominated by transcription. Nucleic Acids Res. 2022 05 06; 50(8):4436-4449.
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Supercoiling and looping promote DNA base accessibility and coordination among distant sites. Nat Commun. 2021 09 28; 12(1):5683.
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Mechanical Properties of Transcription. Phys Rev Lett. 2017 Jun 30; 118(26):268101.
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Effects of Circular DNA Length on Transfection Efficiency by Electroporation into HeLa Cells. PLoS One. 2016; 11(12):e0167537.
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Mechanical bounds to transcriptional noise. Proc Natl Acad Sci U S A. 2016 12 06; 113(49):13983-13988.