"DNA, Circular" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Any of the covalently closed DNA molecules found in bacteria, many viruses, mitochondria, plastids, and plasmids. Small, polydisperse circular DNA's have also been observed in a number of eukaryotic organisms and are suggested to have homology with chromosomal DNA and the capacity to be inserted into, and excised from, chromosomal DNA. It is a fragment of DNA formed by a process of looping out and deletion, containing a constant region of the mu heavy chain and the 3'-part of the mu switch region. Circular DNA is a normal product of rearrangement among gene segments encoding the variable regions of immunoglobulin light and heavy chains, as well as the T-cell receptor. (Riger et al., Glossary of Genetics, 5th ed & Segen, Dictionary of Modern Medicine, 1992)
| Descriptor ID |
D004270
|
| MeSH Number(s) |
D13.444.308.283 G02.111.570.820.486.212 G05.360.580.156
|
| Concept/Terms |
DNA, Circular- DNA, Circular
- Circular DNAs
- DNAs, Circular
- Circular DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA, Circular".
Below are MeSH descriptors whose meaning is more specific than "DNA, Circular".
This graph shows the total number of publications written about "DNA, Circular" by people in this website by year, and whether "DNA, Circular" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA, Circular" by people in Profiles.
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Combinatorial RNA Interference Therapy Prevents Selection of Pre-existing HBV Variants in Human Liver Chimeric Mice. Sci Rep. 2015 Oct 20; 5:15259.
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Assaying for the dual incisions of nucleotide excision repair using DNA with a lesion at a specific site. Methods Mol Biol. 2006; 314:435-56.
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Effects of perturbing nucleoid structure on nucleoid occlusion-mediated toporegulation of FtsZ ring assembly. J Bacteriol. 2004 Jun; 186(12):3951-9.
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Formation of circular amplifications in Saccharomyces cerevisiae by a breakage-fusion-bridge mechanism. Environ Mol Mutagen. 2000; 36(2):113-20.
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Dual-incision assays for nucleotide excision repair using DNA with a lesion at a specific site. Methods Mol Biol. 1999; 113:373-92.
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Initiation and bidirectional propagation of chromatin assembly from a target site for nucleotide excision repair. EMBO J. 1997 10 15; 16(20):6281-9.
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Analysis of incision sites produced by human cell extracts and purified proteins during nucleotide excision repair of a 1,3-intrastrand d(GpTpG)-cisplatin adduct. J Biol Chem. 1996 Mar 22; 271(12):7177-86.
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The global transcriptional regulators, SSN6 and TUP1, play distinct roles in the establishment of a repressive chromatin structure. Genes Dev. 1994 Jun 15; 8(12):1400-10.
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Repair by human cell extracts of single (6-4) and cyclobutane thymine-thymine photoproducts in DNA. Proc Natl Acad Sci U S A. 1993 Nov 01; 90(21):9823-7.
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A quantitative assay for fragmented DNA in apoptotic cells. Anal Biochem. 1992 Nov 15; 207(1):163-7.