"DNA, Antisense" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
DNA that is complementary to the sense strand. (The sense strand has the same sequence as the mRNA transcript. The antisense strand is the template for mRNA synthesis.) Synthetic antisense DNAs are used to hybridize to complementary sequences in target RNAs or DNAs to effect the functioning of specific genes for investigative or therapeutic purposes.
Descriptor ID |
D016373
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MeSH Number(s) |
D13.150.200 D13.444.308.150 D13.444.600.150.200 D27.720.470.530.600.150.200
|
Concept/Terms |
DNA, Antisense- DNA, Antisense
- Anti-Sense DNA
- Anti Sense DNA
- DNA, Anti-Sense
- Antisense DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA, Antisense".
Below are MeSH descriptors whose meaning is more specific than "DNA, Antisense".
This graph shows the total number of publications written about "DNA, Antisense" by people in this website by year, and whether "DNA, Antisense" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2005 | 1 | 2 | 3 |
2006 | 1 | 0 | 1 |
2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA, Antisense" by people in Profiles.
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Human T-cell leukemia virus type 3 (HTLV-3) and HTLV-4 antisense-transcript-encoded proteins interact and transactivate Jun family-dependent transcription via their atypical bZIP motif. J Virol. 2014 Aug; 88(16):8956-70.
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Novel role of RGS2 in regulation of antioxidant homeostasis in neuronal cells. FEBS Lett. 2011 May 06; 585(9):1375-81.
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Tumor-suppressor activity of RRIG1 in breast cancer. BMC Cancer. 2011 Jan 25; 11:32.
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Intratumoral epidermal growth factor receptor antisense DNA therapy in head and neck cancer: first human application and potential antitumor mechanisms. J Clin Oncol. 2009 Mar 10; 27(8):1235-42.
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Production of VEGF165 by Ewing's sarcoma cells induces vasculogenesis and the incorporation of CD34+ stem cells into the expanding tumor vasculature. Int J Cancer. 2006 Aug 15; 119(4):839-46.
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HTLV-I antisense transcripts initiating in the 3'LTR are alternatively spliced and polyadenylated. Retrovirology. 2006 Mar 02; 3:15.
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cFos is critical for MCF-7 breast cancer cell growth. Oncogene. 2005 Sep 29; 24(43):6516-24.
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PAC1 receptors mediate pituitary adenylate cyclase-activating polypeptide- and progesterone-facilitated receptivity in female rats. Mol Endocrinol. 2005 Nov; 19(11):2798-811.
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TIMP-1 antisense gene transfection attenuates the invasive potential of pancreatic cancer cells in vitro and inhibits tumor growth in vivo. Am J Surg. 2005 Jun; 189(6):675-9.
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Targeting Survivin expression induces cell proliferation defect and subsequent cell death involving mitochondrial pathway in myeloid leukemic cells. Cell Cycle. 2003 Sep-Oct; 2(5):488-93.