Oligonucleotides, Antisense
"Oligonucleotides, Antisense" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Short fragments of DNA or RNA that are used to alter the function of target RNAs or DNAs to which they hybridize.
| Descriptor ID |
D016376
|
| MeSH Number(s) |
D13.150.480 D13.444.600.150.640 D13.695.578.424.480 D27.720.470.530.600.150.640
|
| Concept/Terms |
Oligonucleotides, Antisense- Oligonucleotides, Antisense
- Antisense Oligonucleotides
- Anti-Sense Oligonucleotides
- Anti Sense Oligonucleotides
- Oligonucleotides, Anti-Sense
|
Below are MeSH descriptors whose meaning is more general than "Oligonucleotides, Antisense".
Below are MeSH descriptors whose meaning is more specific than "Oligonucleotides, Antisense".
This graph shows the total number of publications written about "Oligonucleotides, Antisense" by people in this website by year, and whether "Oligonucleotides, Antisense" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 2 | 2 |
| 1997 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 1 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 3 | 3 |
| 2005 | 1 | 2 | 3 |
| 2006 | 1 | 1 | 2 |
| 2007 | 2 | 1 | 3 |
| 2009 | 0 | 2 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 3 | 3 | 6 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 2 | 2 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 2 | 2 |
| 2023 | 1 | 1 | 2 |
| 2024 | 3 | 0 | 3 |
| 2025 | 4 | 2 | 6 |
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Below are the most recent publications written about "Oligonucleotides, Antisense" by people in Profiles.
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Uncovering ASO-Targetable Deep Intronic AIRE Variants: Insights and Therapeutic Implications. DNA Cell Biol. 2025 Jan; 44(1):1-5.
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A deep intronic splice-altering AIRE variant causes APECED syndrome through antisense oligonucleotide-targetable pseudoexon inclusion. Sci Transl Med. 2024 09 18; 16(765):eadk0845.
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Antisense oligonucleotide therapy rescues disturbed brain rhythms and sleep in juvenile and adult mouse models of Angelman syndrome. Elife. 2023 01 03; 12.
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Antisense oligonucleotide therapy in a humanized mouse model of MECP2 duplication syndrome. Sci Transl Med. 2021 03 03; 13(583).
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Reversal of phenotypes in MECP2 duplication mice using genetic rescue or antisense oligonucleotides. Nature. 2015 Dec 03; 528(7580):123-6.
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Small molecule compounds targeting miRNAs for cancer therapy. Adv Drug Deliv Rev. 2015 Jan; 81:104-16.
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Balancing GRK2 and EPAC1 levels prevents and relieves chronic pain. J Clin Invest. 2013 Dec; 123(12):5023-34.
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XIAP downregulation promotes caspase-dependent inhibition of proteasome activity in AML cells. Leuk Res. 2013 Aug; 37(8):974-9.
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MicroRNA therapeutics: principles, expectations, and challenges. Chin J Cancer. 2011 Jun; 30(6):368-70.
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Expression of ARC (apoptosis repressor with caspase recruitment domain), an antiapoptotic protein, is strongly prognostic in AML. Blood. 2011 Jan 20; 117(3):780-7.