"Aptamers, Nucleotide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nucleotide sequences, generated by iterative rounds of SELEX APTAMER TECHNIQUE, that bind to a target molecule specifically and with high affinity.
| Descriptor ID |
D052157
|
| MeSH Number(s) |
D13.695.578.424.224
|
| Concept/Terms |
RNA Aptamers- RNA Aptamers
- Aptamers, RNA
- Oligonucleotide Ligands, RNA
- RNA Oligonucleotide Ligands
DNA Aptamers- DNA Aptamers
- Aptamers, DNA
- Oligonucleotide Ligands, DNA
- DNA Oligonucleotide Ligands
|
Below are MeSH descriptors whose meaning is more general than "Aptamers, Nucleotide".
Below are MeSH descriptors whose meaning is more specific than "Aptamers, Nucleotide".
This graph shows the total number of publications written about "Aptamers, Nucleotide" by people in this website by year, and whether "Aptamers, Nucleotide" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 1 | 3 |
| 2011 | 3 | 0 | 3 |
| 2012 | 2 | 0 | 2 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 3 | 0 | 3 |
| 2021 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
| 2025 | 4 | 0 | 4 |
| 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Aptamers, Nucleotide" by people in Profiles.
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Cross-ancestry comparison of aptamer and antibody protein measures. Nat Commun. 2026 Jan 22; 17(1):1054.
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Avacincaptad Pegol for Geographic Atrophy Secondary to Age-Related Macular Degeneration: Two-Year Efficacy and Safety Results from the GATHER2 Phase 3 Trial. Ophthalmology. 2026 Apr; 133(4):451-465.
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Injectable aptamer-functionalized nucleic acid-collagen hydrogels as a bioactive platform for angiogenic applications. Biomater Adv. 2026 Mar; 180:214580.
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Disruption of the Nucleolin-CXCR4 interaction by the DNA aptamer HY-4 halts colorectal cancer metastasis. Mol Ther. 2025 Oct 01; 33(10):4904-4922.
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Aptamer-conjugated gold nanoparticles enable oligonucleotide delivery into muscle stem cells to promote regeneration of dystrophic muscles. Nat Commun. 2025 Jan 10; 16(1):577.
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Symmetry breaking of fluorophore binding to a G-quadruplex generates an RNA aptamer with picomolar KD. Nucleic Acids Res. 2024 Aug 12; 52(14):8039-8051.
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Efficacy and safety of avacincaptad pegol in patients with geographic atrophy (GATHER2): 12-month results from a randomised, double-masked, phase 3 trial. Lancet. 2023 Oct 21; 402(10411):1449-1458.
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A Non-G-Quadruplex DNA Aptamer Targeting NCL for Diagnosis and Therapy in Bladder Cancer. Adv Healthc Mater. 2023 08; 12(20):e2300791.
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Development of an Aptamer-Based Electrochemical Microfluidic Device for Viral Vaccine Quantitation. Anal Chem. 2022 04 26; 94(16):6146-6155.
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Effect of Sequence on the Interactions of Divalent Cations with M-Box Riboswitches from Mycobacterium tuberculosis and Bacillus subtilis. Biochemistry. 2021 09 21; 60(37):2781-2794.