"Aptamers, Nucleotide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nucleotide sequences, generated by iterative rounds of SELEX APTAMER TECHNIQUE, that bind to a target molecule specifically and with high affinity.
| Descriptor ID |
D052157
|
| MeSH Number(s) |
D13.695.578.424.224
|
| Concept/Terms |
RNA Aptamers- RNA Aptamers
- Aptamers, RNA
- Oligonucleotide Ligands, RNA
- RNA Oligonucleotide Ligands
DNA Aptamers- DNA Aptamers
- Aptamers, DNA
- Oligonucleotide Ligands, DNA
- DNA Oligonucleotide Ligands
|
Below are MeSH descriptors whose meaning is more general than "Aptamers, Nucleotide".
Below are MeSH descriptors whose meaning is more specific than "Aptamers, Nucleotide".
This graph shows the total number of publications written about "Aptamers, Nucleotide" by people in this website by year, and whether "Aptamers, Nucleotide" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 2009 | 2 | 0 | 2 |
| 2010 | 4 | 2 | 6 |
| 2011 | 4 | 0 | 4 |
| 2012 | 3 | 0 | 3 |
| 2013 | 3 | 1 | 4 |
| 2014 | 1 | 0 | 1 |
| 2016 | 4 | 1 | 5 |
| 2017 | 2 | 0 | 2 |
| 2018 | 1 | 1 | 2 |
| 2020 | 1 | 1 | 2 |
| 2021 | 2 | 1 | 3 |
| 2022 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
| 2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "Aptamers, Nucleotide" by people in Profiles.
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Symmetry breaking of fluorophore binding to a G-quadruplex generates an RNA aptamer with picomolar KD. Nucleic Acids Res. 2024 Aug 12; 52(14):8039-8051.
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Aptamers in neuro-oncology: An emerging therapeutic modality. Neuro Oncol. 2024 01 05; 26(1):38-54.
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A Non-G-Quadruplex DNA Aptamer Targeting NCL for Diagnosis and Therapy in Bladder Cancer. Adv Healthc Mater. 2023 08; 12(20):e2300791.
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Cell-directed aptamer therapeutic targeting for cancers including those within the central nervous system. Oncoimmunology. 2022; 11(1):2062827.
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Effect of Sequence on the Interactions of Divalent Cations with M-Box Riboswitches from Mycobacterium tuberculosis and Bacillus subtilis. Biochemistry. 2021 09 21; 60(37):2781-2794.
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Comprehensive aptamer-based screen of 1317 proteins uncovers improved stool protein markers of colorectal cancer. J Gastroenterol. 2021 07; 56(7):659-672.
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Conversion of RNA Aptamer into Modified DNA Aptamers Provides for Prolonged Stability and Enhanced Antitumor Activity. J Am Chem Soc. 2021 05 26; 143(20):7655-7670.
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X-aptamers targeting Thy-1 membrane glycoprotein in pancreatic ductal adenocarcinoma. Biochimie. 2021 Feb; 181:25-33.
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Growth Factor Midkine Aggravates Pulmonary Arterial Hypertension via Surface Nucleolin. Sci Rep. 2020 06 25; 10(1):10345.
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Osteopontin mediates glioblastoma-associated macrophage infiltration and is a potential therapeutic target. J Clin Invest. 2019 01 02; 129(1):137-149.