"Aptamers, Nucleotide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nucleotide sequences, generated by iterative rounds of SELEX APTAMER TECHNIQUE, that bind to a target molecule specifically and with high affinity.
| Descriptor ID |
D052157
|
| MeSH Number(s) |
D13.695.578.424.224
|
| Concept/Terms |
RNA Aptamers- RNA Aptamers
- Aptamers, RNA
- Oligonucleotide Ligands, RNA
- RNA Oligonucleotide Ligands
DNA Aptamers- DNA Aptamers
- Aptamers, DNA
- Oligonucleotide Ligands, DNA
- DNA Oligonucleotide Ligands
|
Below are MeSH descriptors whose meaning is more general than "Aptamers, Nucleotide".
Below are MeSH descriptors whose meaning is more specific than "Aptamers, Nucleotide".
This graph shows the total number of publications written about "Aptamers, Nucleotide" by people in this website by year, and whether "Aptamers, Nucleotide" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 1 | 3 |
| 2011 | 4 | 0 | 4 |
| 2012 | 2 | 0 | 2 |
| 2013 | 2 | 1 | 3 |
| 2014 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 2 | 0 | 2 |
| 2021 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
| 2023 | 3 | 0 | 3 |
| 2024 | 1 | 1 | 2 |
| 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "Aptamers, Nucleotide" by people in Profiles.
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Disruption of the Nucleolin-CXCR4 interaction by the DNA aptamer HY-4 halts colorectal cancer metastasis. Mol Ther. 2025 Oct 01; 33(10):4904-4922.
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Aptamer-conjugated gold nanoparticles enable oligonucleotide delivery into muscle stem cells to promote regeneration of dystrophic muscles. Nat Commun. 2025 Jan 10; 16(1):577.
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RNA-Puzzles Round V: blind predictions of 23 RNA structures. Nat Methods. 2025 Feb; 22(2):399-411.
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Symmetry breaking of fluorophore binding to a G-quadruplex generates an RNA aptamer with picomolar KD. Nucleic Acids Res. 2024 Aug 12; 52(14):8039-8051.
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Aptamers in neuro-oncology: An emerging therapeutic modality. Neuro Oncol. 2024 01 05; 26(1):38-54.
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Efficacy and safety of avacincaptad pegol in patients with geographic atrophy (GATHER2): 12-month results from a randomised, double-masked, phase 3 trial. Lancet. 2023 Oct 21; 402(10411):1449-1458.
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A Non-G-Quadruplex DNA Aptamer Targeting NCL for Diagnosis and Therapy in Bladder Cancer. Adv Healthc Mater. 2023 08; 12(20):e2300791.
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An aptamer-based depot system for sustained release of small molecule therapeutics. Nat Commun. 2023 04 28; 14(1):2444.
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Cell-directed aptamer therapeutic targeting for cancers including those within the central nervous system. Oncoimmunology. 2022; 11(1):2062827.
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Development of an Aptamer-Based Electrochemical Microfluidic Device for Viral Vaccine Quantitation. Anal Chem. 2022 04 26; 94(16):6146-6155.