"Gene Products, tax" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Transcriptional trans-acting proteins of the promoter elements found in the long terminal repeats (LTR) of HUMAN T-LYMPHOTROPIC VIRUS 1 and HUMAN T-LYMPHOTROPIC VIRUS 2. The tax (trans-activator x; x is undefined) proteins act by binding to enhancer elements in the LTR.
| Descriptor ID |
D016356
|
| MeSH Number(s) |
D12.776.624.664.520.750.480 D12.776.964.700.750.480 D12.776.964.775.750.480 D12.776.964.925.984.410
|
| Concept/Terms |
Gene Products, tax- Gene Products, tax
- p40 tax
- p40(tax)
- tax Gene Products
- tax Protein
- Transforming Antigen p40x
- Antigen p40x, Transforming
- p40x, Transforming Antigen
- Trans-Activator Protein p40(tax)
- Trans-Activator Protein p40(x)
- Trans-Activator Protein p40x
- Trans Activator Protein p40x
- p40x, Trans-Activator Protein
- Trans-Activator Protein pX
- Trans Activator Protein pX
- pX, Trans-Activator Protein
- Transactivator p40(tax)
- Transactivator Protein p40(x)
- Gene Product, tax
- tax Gene Product
- Trans-Activator Protein p40(lor)
|
Below are MeSH descriptors whose meaning is more general than "Gene Products, tax".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Neoplasm Proteins [D12.776.624]
- Oncogene Proteins [D12.776.624.664]
- Oncogene Proteins, Viral [D12.776.624.664.520]
- Retroviridae Proteins, Oncogenic [D12.776.624.664.520.750]
- Gene Products, tax [D12.776.624.664.520.750.480]
- Viral Proteins [D12.776.964]
- Oncogene Proteins, Viral [D12.776.964.700]
- Retroviridae Proteins, Oncogenic [D12.776.964.700.750]
- Gene Products, tax [D12.776.964.700.750.480]
- Retroviridae Proteins [D12.776.964.775]
- Retroviridae Proteins, Oncogenic [D12.776.964.775.750]
- Gene Products, tax [D12.776.964.775.750.480]
- Viral Regulatory and Accessory Proteins [D12.776.964.925]
- Trans-Activators [D12.776.964.925.984]
- Gene Products, tax [D12.776.964.925.984.410]
Below are MeSH descriptors whose meaning is more specific than "Gene Products, tax".
This graph shows the total number of publications written about "Gene Products, tax" by people in this website by year, and whether "Gene Products, tax" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 0 | 2 |
| 1995 | 1 | 0 | 1 |
| 1996 | 4 | 2 | 6 |
| 1997 | 4 | 1 | 5 |
| 1998 | 6 | 0 | 6 |
| 1999 | 3 | 0 | 3 |
| 2000 | 8 | 1 | 9 |
| 2001 | 4 | 0 | 4 |
| 2002 | 2 | 0 | 2 |
| 2003 | 2 | 0 | 2 |
| 2004 | 0 | 3 | 3 |
| 2005 | 4 | 0 | 4 |
| 2006 | 2 | 1 | 3 |
| 2007 | 3 | 1 | 4 |
| 2008 | 2 | 2 | 4 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 3 | 0 | 3 |
| 2012 | 3 | 0 | 3 |
| 2013 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Gene Products, tax" by people in Profiles.
-
HTLV-1 Tax plugs and freezes UPF1 helicase leading to nonsense-mediated mRNA decay inhibition. Nat Commun. 2018 01 30; 9(1):431.
-
Lack of recall response to Tax in ATL and HAM/TSP patients but not in asymptomatic carriers of human T-cell leukemia virus type 1. J Clin Immunol. 2013 Oct; 33(7):1223-39.
-
Activation of WIP1 phosphatase by HTLV-1 Tax mitigates the cellular response to DNA damage. PLoS One. 2013; 8(2):e55989.
-
Wip1 and p53 contribute to HTLV-1 Tax-induced tumorigenesis. Retrovirology. 2012 Dec 21; 9:114.
-
HTLV-2 Tax immortalizes human CD4+ memory T lymphocytes by oncogenic activation and dysregulation of autophagy. J Biol Chem. 2012 Oct 05; 287(41):34683-93.
-
New insight into the oncogenic mechanism of the retroviral oncoprotein Tax. Protein Cell. 2012 Aug; 3(8):581-9.
-
Human T-cell lymphotropic virus type 3 (HTLV-3)- and HTLV-4-derived antisense transcripts encode proteins with similar Tax-inhibiting functions but distinct subcellular localization. J Virol. 2011 Dec; 85(23):12673-85.
-
The HTLV-1 Tax oncoprotein represses Ku80 gene expression. Virology. 2011 Jul 20; 416(1-2):1-8.
-
Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-kappaB signaling. J Virol. 2011 Jul; 85(13):6212-9.
-
The ARF tumor suppressor regulates bone remodeling and osteosarcoma development in mice. PLoS One. 2010 Dec 30; 5(12):e15755.