"Gene Products, rev" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Trans-acting nuclear proteins whose functional expression are required for retroviral replication. Specifically, the rev gene products are required for processing and translation of the gag and env mRNAs, and thus rev regulates the expression of the viral structural proteins. rev can also regulate viral regulatory proteins. A cis-acting antirepression sequence (CAR) in env, also known as the rev-responsive element (RRE), is responsive to the rev gene product. rev is short for regulator of virion.
| Descriptor ID |
D015694
|
| MeSH Number(s) |
D12.776.157.725.076 D12.776.664.962.186 D12.776.964.925.984.385
|
| Concept/Terms |
Gene Products, rev- Gene Products, rev
- rev Gene Products
- rev Protein
- Gene Product, rev
- rev Gene Product
|
Below are MeSH descriptors whose meaning is more general than "Gene Products, rev".
Below are MeSH descriptors whose meaning is more specific than "Gene Products, rev".
This graph shows the total number of publications written about "Gene Products, rev" by people in this website by year, and whether "Gene Products, rev" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 |
| 1996 | 0 | 1 | 1 |
| 1997 | 1 | 1 | 2 |
| 2000 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Gene Products, rev" by people in Profiles.
-
Novel Function of Rev-erba in Promoting Brown Adipogenesis. Sci Rep. 2015 Jun 10; 5:11239.
-
Role of viral regulatory and accessory proteins in HIV-1 replication. Front Biosci. 2004 Sep 01; 9:2388-413.
-
The fragile X-related proteins FXR1P and FXR2P contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins. Hum Mol Genet. 2000 Jun 12; 9(10):1487-93.
-
A naturally arising mutation of a potential silencer of exon splicing in human immunodeficiency virus type 1 induces dominant aberrant splicing and arrests virus production. J Virol. 1997 Nov; 71(11):8542-51.
-
Protection of primary human T cells from HIV infection by Trev: a transdominant fusion gene. Hum Gene Ther. 1997 May 01; 8(7):861-8.
-
A chimeric human immunodeficiency virus type 1 (HIV-1) minimal Rev response element-ribozyme molecule exhibits dual antiviral function and inhibits cell-cell transmission of HIV-1. J Virol. 1996 Mar; 70(3):1596-601.
-
Localization of human immunodeficiency virus Rev in transfected and virus-infected cells. AIDS Res Hum Retroviruses. 1995 Jul; 11(7):795-804.
-
Inhibition of HIV-1 by a double transdominant fusion gene. Gene Ther. 1995 May; 2(3):181-6.
-
Stable expression of transdominant Rev protein in human T cells inhibits human immunodeficiency virus replication. J Exp Med. 1992 Oct 01; 176(4):1197-201.