Iron Regulatory Protein 1
"Iron Regulatory Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multifunctional iron-sulfur protein that is both an iron regulatory protein and cytoplasmic form of aconitate hydratase. It binds to iron regulatory elements found on mRNAs involved in iron metabolism and regulates their translation. Its RNA binding ability and its aconitate hydrolase activity are dependent upon availability of IRON.
| Descriptor ID |
D035941
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| MeSH Number(s) |
D08.811.520.241.300.050.500 D12.776.157.427.374.375.960 D12.776.157.725.374 D12.776.494.500 D12.776.556.579.374.375.960 D12.776.664.962.374
|
| Concept/Terms |
Iron Regulatory Protein 1- Iron Regulatory Protein 1
- IRP-1 Protein
- IRP 1 Protein
- IRP1 Protein
- ACO1 Protein
- Aconitase 1, Soluble
- Soluble Aconitase 1
- IRE-BP1
- IRE BP1
- Ferritin Repressor Protein
- Repressor Protein, Ferritin
|
Below are MeSH descriptors whose meaning is more general than "Iron Regulatory Protein 1".
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This graph shows the total number of publications written about "Iron Regulatory Protein 1" by people in this website by year, and whether "Iron Regulatory Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
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Below are the most recent publications written about "Iron Regulatory Protein 1" by people in Profiles.
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Molecular characterization of a second iron-responsive element binding protein, iron regulatory protein 2. Structure, function, and post-translational regulation. J Biol Chem. 1994 Dec 09; 269(49):30904-10.