"Iron-Regulatory Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that regulate cellular and organismal iron homeostasis. They play an important biological role by maintaining iron levels that are adequate for metabolic need, but below the toxicity threshold.
Descriptor ID |
D035925
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MeSH Number(s) |
D12.776.494
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Concept/Terms |
Iron-Regulatory Proteins- Iron-Regulatory Proteins
- Iron Regulatory Proteins
- Iron-Regulatory Protein
- Iron Regulatory Protein
- Iron Regulatory Factor
- Regulatory Factor, Iron
- Iron-Response Proteins
- Iron Response Proteins
Iron-Responsive Element Binding Proteins- Iron-Responsive Element Binding Proteins
- Iron Responsive Element Binding Proteins
- IRE-BP
- Iron-Responsive Elements-Binding Protein
- Iron Responsive Elements Binding Protein
- IRE-Binding Protein
- IRE Binding Protein
|
Below are MeSH descriptors whose meaning is more general than "Iron-Regulatory Proteins".
Below are MeSH descriptors whose meaning is more specific than "Iron-Regulatory Proteins".
This graph shows the total number of publications written about "Iron-Regulatory Proteins" by people in this website by year, and whether "Iron-Regulatory Proteins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 1 | 1 |
2001 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Iron-Regulatory Proteins" by people in Profiles.
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Examination of HFE associations with childhood leukemia risk and extension to other iron regulatory genes. Leuk Res. 2014 Sep; 38(9):1055-60.
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A mechanistic study of proteasome inhibition-induced iron misregulation in dopamine neuron degeneration. Neurosignals. 2012; 20(4):223-36.
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Iron treatment downregulates DMT1 and IREG1 mRNA expression in Caco-2 cells. J Nutr. 2002 Apr; 132(4):693-6.
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Targeting HER-2/neu-overexpressing breast cancer cells by an antisense iron responsive element-directed gene expression. Cancer Lett. 2001 Dec 28; 174(2):151-8.
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Molecular characterization of a second iron-responsive element binding protein, iron regulatory protein 2. Structure, function, and post-translational regulation. J Biol Chem. 1994 Dec 09; 269(49):30904-10.
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An iron-sulfur cluster plays a novel regulatory role in the iron-responsive element binding protein. Biometals. 1992; 5(3):131-40.
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Cloning of the cDNA encoding an RNA regulatory protein--the human iron-responsive element-binding protein. Proc Natl Acad Sci U S A. 1990 Oct; 87(20):7958-62.