"Molecular Chaperones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of cellular proteins that mediate the correct assembly or disassembly of polypeptides and their associated ligands. Although they take part in the assembly process, molecular chaperones are not components of the final structures.
| Descriptor ID |
D018832
|
| MeSH Number(s) |
D12.776.580
|
| Concept/Terms |
Molecular Chaperones- Molecular Chaperones
- Molecular Chaperone
- Chaperone, Molecular
- Chaperones, Molecular
|
Below are MeSH descriptors whose meaning is more general than "Molecular Chaperones".
Below are MeSH descriptors whose meaning is more specific than "Molecular Chaperones".
This graph shows the total number of publications written about "Molecular Chaperones" by people in this website by year, and whether "Molecular Chaperones" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1998 | 2 | 1 | 3 |
| 1999 | 2 | 3 | 5 |
| 2000 | 5 | 2 | 7 |
| 2001 | 0 | 3 | 3 |
| 2002 | 3 | 3 | 6 |
| 2003 | 4 | 3 | 7 |
| 2004 | 4 | 1 | 5 |
| 2005 | 3 | 6 | 9 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 2 | 3 |
| 2008 | 3 | 2 | 5 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 3 | 3 |
| 2011 | 0 | 4 | 4 |
| 2012 | 2 | 2 | 4 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 3 | 4 |
| 2015 | 1 | 4 | 5 |
| 2016 | 2 | 2 | 4 |
| 2017 | 3 | 1 | 4 |
| 2018 | 2 | 1 | 3 |
| 2020 | 2 | 0 | 2 |
| 2021 | 1 | 4 | 5 |
| 2022 | 2 | 4 | 6 |
| 2023 | 2 | 3 | 5 |
| 2024 | 0 | 2 | 2 |
| 2025 | 2 | 0 | 2 |
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click here.
Below are the most recent publications written about "Molecular Chaperones" by people in Profiles.
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Loss of the lysosomal protein CLN3 triggers c-Abl-dependent YAP1 pro-apoptotic signaling. EMBO Rep. 2025 Dec; 26(24):6096-6120.
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Speech, Language and Non-verbal Communication in CLN2 and CLN3 Batten Disease. J Inherit Metab Dis. 2025 01; 48(1):e12838.
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Cardiac-specific deletion of heat shock protein 60 induces mitochondrial stress and disrupts heart development in mice. Biochem Biophys Res Commun. 2024 05 28; 710:149883.
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Sodium Butyrate Inhibits the Malignant Proliferation of Colon Cancer Cells via the miR-183/DNAJB4 Axis. Biochem Genet. 2024 Oct; 62(5):4174-4190.
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Upregulation of tumor suppressor PIAS3 by Honokiol promotes tumor cell apoptosis via selective inhibition of STAT3 tyrosine 705 phosphorylation. J Nat Med. 2024 Mar; 78(2):285-295.
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Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS. Science. 2023 08 18; 381(6659):794-799.
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The clinical and genetic spectrum of autosomal-recessive TOR1A-related disorders. Brain. 2023 08 01; 146(8):3273-3288.
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Loss of the batten disease protein CLN3 leads to mis-trafficking of M6PR and defective autophagic-lysosomal reformation. Nat Commun. 2023 07 03; 14(1):3911.
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Second Virtual International Symposium on Cellular and Organismal Stress Responses, September 8-9, 2022. Cell Stress Chaperones. 2023 01; 28(1):1-9.
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Deciphering the mechanism and function of Hsp100 unfoldases from protein structure. Biochem Soc Trans. 2022 12 16; 50(6):1725-1736.