"LIM Domain Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large class of structurally-related proteins that contain one or more LIM zinc finger domains. Many of the proteins in this class are involved in intracellular signaling processes and mediate their effects via LIM domain protein-protein interactions. The name LIM is derived from the first three proteins in which the motif was found: LIN-11, Isl1 and Mec-3.
| Descriptor ID |
D060588
|
| MeSH Number(s) |
D12.776.512
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "LIM Domain Proteins".
Below are MeSH descriptors whose meaning is more specific than "LIM Domain Proteins".
This graph shows the total number of publications written about "LIM Domain Proteins" by people in this website by year, and whether "LIM Domain Proteins" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 7 | 7 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 4 | 4 |
| 2007 | 0 | 5 | 5 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 5 | 5 |
| 2011 | 1 | 2 | 3 |
| 2012 | 4 | 1 | 5 |
| 2013 | 3 | 0 | 3 |
| 2014 | 2 | 1 | 3 |
| 2017 | 2 | 2 | 4 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 1 | 2 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "LIM Domain Proteins" by people in Profiles.
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Biologic and Clinical Analysis of Childhood Gamma Delta T-ALL Identifies LMO2/STAG2 Rearrangements as Extremely High Risk. Cancer Discov. 2024 Oct 04; 14(10):1838-1859.
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Exploring the PDZ, DUF, and LIM Domains of Pdlim5 in Dendrite Branching. Int J Mol Sci. 2024 Jul 30; 25(15).
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Molecular insights using spatial transcriptomics of the distal lung in congenital diaphragmatic hernia. Am J Physiol Lung Cell Mol Physiol. 2023 10 01; 325(4):L477-L486.
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Genome-wide CRISPR screen identifies MTA3 as an inducer of gemcitabine resistance in pancreatic ductal adenocarcinoma. Cancer Lett. 2022 11 01; 548:215864.
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Novel phospho-switch function of delta-catenin in dendrite development. J Cell Biol. 2020 11 02; 219(11).
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Wolff-Parkinson-White syndrome: De novo variants and evidence for mutational burden in genes associated with atrial fibrillation. Am J Med Genet A. 2020 06; 182(6):1387-1399.
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LIMS1 Promotes Pancreatic Cancer Cell Survival under Oxygen-Glucose Deprivation Conditions by Enhancing HIF1A Protein Translation. Clin Cancer Res. 2019 07 01; 25(13):4091-4103.
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The islet-expressed Lhx1 transcription factor interacts with Islet-1 and contributes to glucose homeostasis. Am J Physiol Endocrinol Metab. 2019 03 01; 316(3):E397-E409.
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The arginine methyltransferase CARM1 represses p300?ACT?CREMt activity and is required for spermiogenesis. Nucleic Acids Res. 2018 05 18; 46(9):4327-4343.
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Cancer-associated fibroblasts regulate endothelial adhesion protein LPP to promote ovarian cancer chemoresistance. J Clin Invest. 2018 02 01; 128(2):589-606.