"LIM-Homeodomain Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of LIM domain proteins that include an additional centrally-located homeodomain region that binds AT-rich sites on DNA. Many LIM-homeodomain proteins play a role as transcriptional regulators that direct cell fate.
| Descriptor ID |
D060850
|
| MeSH Number(s) |
D12.776.260.529 D12.776.512.249
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "LIM-Homeodomain Proteins".
Below are MeSH descriptors whose meaning is more specific than "LIM-Homeodomain Proteins".
This graph shows the total number of publications written about "LIM-Homeodomain Proteins" by people in this website by year, and whether "LIM-Homeodomain Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 3 | 3 |
| 2008 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 2 | 0 | 2 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "LIM-Homeodomain Proteins" by people in Profiles.
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Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity. Nat Commun. 2019 Jan 22; 10(1):376.
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An Lmx1b-miR135a2 regulatory circuit modulates Wnt1/Wnt signaling and determines the size of the midbrain dopaminergic progenitor pool. PLoS Genet. 2013; 9(12):e1003973.
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TRIP6 regulates p27 KIP1 to promote tumorigenesis. Mol Cell Biol. 2013 Apr; 33(7):1394-409.
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The transcription factor, Lmx1b, promotes a neuronal glutamate phenotype and suppresses a GABA one in the embryonic trigeminal brainstem complex. Somatosens Mot Res. 2012; 29(1):1-12.
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Lmx1a and lmx1b function cooperatively to regulate proliferation, specification, and differentiation of midbrain dopaminergic progenitors. J Neurosci. 2011 Aug 31; 31(35):12413-25.
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Uncoupling skeletal and connective tissue patterning: conditional deletion in cartilage progenitors reveals cell-autonomous requirements for Lmx1b in dorsal-ventral limb patterning. Development. 2010 Apr; 137(7):1181-8.
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Overlapping function of Lmx1a and Lmx1b in anterior hindbrain roof plate formation and cerebellar growth. J Neurosci. 2009 Sep 09; 29(36):11377-84.
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Lmx1b-expressing cells in the mouse limb bud define a dorsal mesenchymal lineage compartment. Genesis. 2009 Apr; 47(4):224-33.
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Manifold functions of the Nail-Patella Syndrome gene Lmx1b in vertebrate development. Dev Growth Differ. 2009 Apr; 51(3):241-50.
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Lmx1b-controlled isthmic organizer is essential for development of midbrain dopaminergic neurons. J Neurosci. 2008 Dec 24; 28(52):14097-106.