"Toll-Like Receptor 9" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pattern recognition receptor that binds unmethylated CPG CLUSTERS. It mediates cellular responses to bacterial pathogens by distinguishing between self and bacterial DNA.
| Descriptor ID |
D051217
|
| MeSH Number(s) |
D12.776.260.750 D12.776.543.750.705.910.500.900
|
| Concept/Terms |
Toll-Like Receptor 9- Toll-Like Receptor 9
- Toll Like Receptor 9
- TLR9 Receptor
- Receptor, TLR9
- TLR9 Protein
- CD289 Antigen
- Antigen, CD289
|
Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptor 9".
Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptor 9".
This graph shows the total number of publications written about "Toll-Like Receptor 9" by people in this website by year, and whether "Toll-Like Receptor 9" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 2 | 2 |
| 2008 | 1 | 2 | 3 |
| 2011 | 3 | 1 | 4 |
| 2012 | 2 | 0 | 2 |
| 2015 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Toll-Like Receptor 9" by people in Profiles.
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TLR2, TLR3, TLR4, TLR9 and TLR11 expression on effector CD4+ T-cell subsets in Leishmania donovani infection. Exp Parasitol. 2023 Dec; 255:108645.
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Unique TLR9 Activation by Helicobacter pylori Depends on the cag T4SS, But Not on VirD2 Relaxases or VirD4 Coupling Proteins. Curr Microbiol. 2022 Mar 03; 79(4):121.
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Overcoming PD-1 Blockade Resistance with CpG-A Toll-Like Receptor 9 Agonist Vidutolimod in Patients with Metastatic Melanoma. Cancer Discov. 2021 12 01; 11(12):2998-3007.
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Induction of antitumor immunity in mice by the combination of nanoparticle-based photothermolysis and anti-PD-1 checkpoint inhibition. Nanomedicine. 2020 04; 25:102169.
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Combined aerosolized Toll-like receptor ligands are an effective therapeutic agent against influenza pneumonia when co-administered with oseltamivir. Eur J Pharmacol. 2018 Jan 05; 818:191-197.
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Autophagosome-lysosome fusion triggers a lysosomal response mediated by TLR9 and controlled by OCRL. Nat Cell Biol. 2016 08; 18(8):839-850.
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Endosomal Toll-Like Receptor Status in Patients with Metabolic Syndrome. Metab Syndr Relat Disord. 2015 Dec; 13(10):477-80.
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Unique Roles of TLR9- and MyD88-Dependent and -Independent Pathways in Adaptive Immune Responses to AAV-Mediated Gene Transfer. J Innate Immun. 2015; 7(3):302-14.
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Toll-like receptor-2/6 and Toll-like receptor-9 agonists suppress viral replication but not airway hyperreactivity in guinea pigs. Am J Respir Cell Mol Biol. 2013 Jun; 48(6):790-6.
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Spontaneous production of immunoglobulin M in human epithelial cancer cells. PLoS One. 2012; 7(12):e51423.