"Toll-Like Receptor 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pattern recognition receptor that interacts with LYMPHOCYTE ANTIGEN 96 and LIPOPOLYSACCHARIDES. It mediates cellular responses to GRAM-NEGATIVE BACTERIA.
| Descriptor ID |
D051197
|
| MeSH Number(s) |
D12.776.543.750.705.910.500.400
|
| Concept/Terms |
Toll-Like Receptor 4- Toll-Like Receptor 4
- Toll Like Receptor 4
- Toll-4 Receptor
- Toll 4 Receptor
- TLR4 Receptor
- Receptor, TLR4
|
Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptor 4".
Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptor 4".
This graph shows the total number of publications written about "Toll-Like Receptor 4" by people in this website by year, and whether "Toll-Like Receptor 4" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 3 | 3 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 3 | 0 | 3 |
| 2006 | 3 | 0 | 3 |
| 2007 | 5 | 2 | 7 |
| 2008 | 3 | 7 | 10 |
| 2009 | 2 | 2 | 4 |
| 2010 | 5 | 5 | 10 |
| 2011 | 6 | 2 | 8 |
| 2012 | 8 | 6 | 14 |
| 2013 | 2 | 3 | 5 |
| 2014 | 6 | 3 | 9 |
| 2015 | 5 | 4 | 9 |
| 2016 | 3 | 3 | 6 |
| 2017 | 4 | 3 | 7 |
| 2018 | 0 | 3 | 3 |
| 2019 | 0 | 4 | 4 |
| 2020 | 4 | 1 | 5 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 6 | 6 |
| 2023 | 1 | 4 | 5 |
| 2024 | 2 | 1 | 3 |
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Below are the most recent publications written about "Toll-Like Receptor 4" by people in Profiles.
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ApoA-I binding protein (AIBP) regulates transient receptor potential vanilloid 1 (TRPV1) activity in rat dorsal root ganglion neurons by selective disruption of toll-like receptor 4 (TLR4)-lipid rafts. Brain Behav Immun. 2025 Jan; 123:644-655.
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In vivo Bruton's tyrosine kinase inhibition attenuates alcohol-associated liver disease by regulating CD84-mediated granulopoiesis. Sci Transl Med. 2024 Aug 07; 16(759):eadg1915.
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Role of gut-derived bacterial lipopolysaccharide and peripheral TLR4 in immobilization stress-induced itch aggravation in a mouse model of atopic dermatitis. Sci Rep. 2024 03 15; 14(1):6263.
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Genetic and immune determinants of E. coli liver abscess formation. Proc Natl Acad Sci U S A. 2023 Dec 19; 120(51):e2310053120.
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TLR2, TLR3, TLR4, TLR9 and TLR11 expression on effector CD4+ T-cell subsets in Leishmania donovani infection. Exp Parasitol. 2023 Dec; 255:108645.
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Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis. Cell Rep. 2023 10 31; 42(10):113240.
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Gene expression profiling and multiplex immunofluorescence analysis of bullous pemphigoid immune-related adverse event reveal upregulation of toll-like receptor 4/complement-induced innate immune response and increased density of TH 1 T-cells. J Cutan Pathol. 2023 Jul; 50(7):661-673.
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Treatment Strategies and Mechanisms Associated with the Prevention of NASH-Associated HCC by a Toll-like Receptor 4 Inhibitor. Cancer Prev Res (Phila). 2023 01 04; 16(1):17-28.
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AIBP regulates TRPV1 activation in chemotherapy-induced peripheral neuropathy by controlling lipid raft dynamics and proximity to TLR4 in dorsal root ganglion neurons. Pain. 2023 06 01; 164(6):e274-e285.
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Histone-stimulated platelet adhesion to mouse cremaster venules in vivo is dependent on von Willebrand factor. Microcirculation. 2022 11; 29(8):e12782.