"Toll-Like Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of pattern recognition receptors characterized by an extracellular leucine-rich domain and a cytoplasmic domain that share homology with the INTERLEUKIN 1 RECEPTOR and the DROSOPHILA toll protein. Following pathogen recognition, toll-like receptors recruit and activate a variety of SIGNAL TRANSDUCING ADAPTOR PROTEINS.
| Descriptor ID |
D051193
|
| MeSH Number(s) |
D12.776.543.750.705.910.500
|
| Concept/Terms |
Toll-Like Receptors- Toll-Like Receptors
- Toll Like Receptors
- Toll-Like Receptor
- Receptor, Toll-Like
- Toll Like Receptor
- Receptors, Toll-Like
- Receptors, Toll Like
|
Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptors".
Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptors".
This graph shows the total number of publications written about "Toll-Like Receptors" by people in this website by year, and whether "Toll-Like Receptors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 5 | 5 |
| 2003 | 0 | 4 | 4 |
| 2004 | 0 | 7 | 7 |
| 2005 | 0 | 3 | 3 |
| 2006 | 4 | 2 | 6 |
| 2007 | 1 | 3 | 4 |
| 2008 | 3 | 2 | 5 |
| 2009 | 6 | 2 | 8 |
| 2010 | 5 | 5 | 10 |
| 2011 | 4 | 4 | 8 |
| 2012 | 4 | 1 | 5 |
| 2013 | 8 | 3 | 11 |
| 2014 | 4 | 5 | 9 |
| 2015 | 2 | 1 | 3 |
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 3 | 4 |
| 2018 | 1 | 2 | 3 |
| 2019 | 3 | 0 | 3 |
| 2020 | 0 | 1 | 1 |
| 2021 | 2 | 1 | 3 |
| 2023 | 0 | 3 | 3 |
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Below are the most recent publications written about "Toll-Like Receptors" by people in Profiles.
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Effect of epithelial-specific MyD88 signaling pathway on airway inflammatory response to organic dust exposure. J Immunotoxicol. 2023 12; 20(1):2148782.
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TLR2, TLR3, TLR4, TLR9 and TLR11 expression on effector CD4+ T-cell subsets in Leishmania donovani infection. Exp Parasitol. 2023 Dec; 255:108645.
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Toll-like receptors 2, 4, and 9 modulate promoting effect of COPD-like airway inflammation on K-ras-driven lung cancer through activation of the MyD88/NF-?B pathway in the airway epithelium. Front Immunol. 2023; 14:1118721.
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Selective Modulation of the Pulmonary Innate Immune Response Does Not Change Lung Microbiota in Healthy Mice. Am J Respir Crit Care Med. 2021 09 15; 204(6):734-736.
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Phase I/II trial of a long peptide vaccine (LPV7) plus toll-like receptor (TLR) agonists with or without incomplete Freund's adjuvant (IFA) for resected high-risk melanoma. J Immunother Cancer. 2021 08; 9(8).
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Interdependencies between Toll-like receptors in Leishmania infection. Immunology. 2021 09; 164(1):173-189.
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Adaptive response to inflammation contributes to sustained myelopoiesis and confers a competitive advantage in myelodysplastic syndrome HSCs. Nat Immunol. 2020 05; 21(5):535-545.
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How do endosomal Toll-like receptors sense and extend ischaemic myocardial injury? Cardiovasc Res. 2019 10 01; 115(12):1687-1689.
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The Interaction Between Two Worlds: MicroRNAs and Toll-Like Receptors. Front Immunol. 2019; 10:1053.
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Inducible lung epithelial resistance requires multisource reactive oxygen species generation to protect against bacterial infections. PLoS One. 2019; 14(2):e0208216.