SANJIV SUR

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
AddressOne Baylor Plaza
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Govindhan A, Sur A, Hosoki K, Sur S. Single-nucleus RNA sequencing identifies conserved structural cell programs in allergic lung inflammation. J Allergy Clin Immunol Glob. 2026 Jul; 5(4):100710. PMID: 42199635; PMCID: PMC13200110.
      Citations:    
    2. Hosoki K, Govindhan A, Sur S. STING stimulates recruitment of inflammatory cells and airway fibrosis in chronic allergic airway inflammation. J Allergy Clin Immunol. 2025 Oct; 156(4):1120-1123. PMID: 40668173.
      Citations:    Fields:    
    3. Hosoki K, Govindhan A, Knight JM, Sur S. Allosteric inhibition of CXCR1 and CXCR2 abrogates Th2/Th17-associated Allergic Lung Inflammation in Mice. bioRxiv. 2024 May 15. PMID: 38798651; PMCID: PMC11118468.
      Citations:    
    4. Tapryal N, Chakraborty A, Saha K, Islam A, Pan L, Hosoki K, Sayed IM, Duran JM, Alcantara J, Castillo V, Tindle C, Sarker AH, Wakamiya M, Cardenas VJ, Sharma G, Crotty Alexander LE, Sur S, Sahoo D, Ghosh G, Das S, Ghosh P, Boldogh I, Hazra TK. The DNA glycosylase NEIL2 is protective during SARS-CoV-2 infection. Nat Commun. 2023 12 09; 14(1):8169. PMID: 38071370; PMCID: PMC10710473.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    5. Hazra T, Tapryal N, Chakraborty A, Rayavara K, Wakamiya M, Islam A, Pan L, Hsu J, Tat V, Maruyama J, Hosoki K, Sayed I, Alcantara J, Castillo V, Tindle C, Sarker A, Cardenas V, Sharma G, Alexander LC, Sur S, Ghosh G, Paessler S, Sahoo D, Ghosh P, Das S, Boldogh I, Tseng CT. The DNA glycosylase NEIL2 plays a vital role in combating SARS-CoV-2 infection. Res Sq. 2022 May 27. PMID: 35665009; PMCID: PMC9164514.
      Citations:    
    6. Hosoki K, Chakraborty A, Hazra TK, Sur S. Protocols to Measure Oxidative Stress and DNA Damage in Asthma. Methods Mol Biol. 2022; 2506:315-332. PMID: 35771481.
      Citations:    Fields:    Translation:AnimalsCells
    7. Tapryal N, Shahabi S, Chakraborty A, Hosoki K, Wakamiya M, Sarkar G, Sharma G, Cardenas VJ, Boldogh I, Sur S, Ghosh G, Hazra TK. Intrapulmonary administration of purified NEIL2 abrogates NF-?B-mediated inflammation. J Biol Chem. 2021 Jan-Jun; 296:100723. PMID: 33932404; PMCID: PMC8164026.
      Citations: 2     Fields:    Translation:AnimalsCells
    8. Hosoki K, Kimata JT, Chakraborty A, Sur S. Reply. J Allergy Clin Immunol. 2020 12; 146(6):1455-1456. PMID: 33077246; PMCID: PMC7522701.
      Citations:    Fields:    Translation:HumansCells
    9. Hosoki K, Chakraborty A, Sur S. Molecular mechanisms and epidemiology of COVID-19 from an allergist's perspective. J Allergy Clin Immunol. 2020 08; 146(2):285-299. PMID: 32624257; PMCID: PMC7331543.
      Citations: 20     Fields:    Translation:HumansCellsPHPublic Health
    10. Wu AY, Sur S, Grant JA, Tripple JW. Interleukin-4/interleukin-13 versus interleukin-5: a comparison of molecular targets in biologic therapy for the treatment of severe asthma. Curr Opin Allergy Clin Immunol. 2019 02; 19(1):30-37. PMID: 30407206.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    11. Hosoki K, Jaruga P, Itazawa T, Aguilera-Aguirre L, Coskun E, Hazra TK, Boldogh I, Dizdaroglu M, Sur S. Excision release of 5?hydroxycytosine oxidatively induced DNA base lesions from the lung genome by cat dander extract challenge stimulates allergic airway inflammation. Clin Exp Allergy. 2018 12; 48(12):1676-1687. PMID: 30244512; PMCID: PMC6588164.
      Citations: 1     Fields:    Translation:Animals
    12. Tian B, Hosoki K, Liu Z, Yang J, Zhao Y, Sun H, Zhou J, Rytting E, Kaphalia L, Calhoun WJ, Sur S, Brasier AR. Mucosal bromodomain-containing protein 4 mediates aeroallergen-induced inflammation and remodeling. J Allergy Clin Immunol. 2019 04; 143(4):1380-1394.e9. PMID: 30321559; PMCID: PMC6490683.
      Citations: 25     Fields:    Translation:HumansAnimals
    13. Hosoki K, Rajarathnam K, Sur S. Attenuation of murine allergic airway inflammation with a CXCR1/CXCR2 chemokine receptor inhibitor. Clin Exp Allergy. 2019 01; 49(1):130-132. PMID: 30218547; PMCID: PMC6660919.
      Citations: 4     Fields:    Translation:Animals
    14. Wu AY, Sur S, Grant JA. Treating insect bite hypersensitivity in horses by using active vaccination against IL-5. J Allergy Clin Immunol. 2018 10; 142(4):1060-1061. PMID: 29981806.
      Citations:    Fields:    Translation:AnimalsPHPublic Health
    15. Zahiruddin AS, Grant JA, Sur S. Role of epigenetics and DNA-damage in asthma. Curr Opin Allergy Clin Immunol. 2018 Feb; 18(1):32-37. PMID: 29189349.
      Citations: 4     Fields:    Translation:HumansAnimals
    16. Chambliss JM, Sur S, Tripple JW. Asthma versus chronic obstructive pulmonary disease, the Dutch versus British hypothesis, and role of interleukin-5. Curr Opin Allergy Clin Immunol. 2018 Feb; 18(1):26-31. PMID: 29257776.
      Citations:    
    17. Aguilera-Aguirre L, Hao W, Pan L, Li X, Saavedra-Molina A, Bacsi A, Radak Z, Sur S, Brasier AR, Ba X, Boldogh I. Pollen-induced oxidative DNA damage response regulates miRNAs controlling allergic inflammation. Am J Physiol Lung Cell Mol Physiol. 2017 Dec 01; 313(6):L1058-L1068. PMID: 28798252; PMCID: PMC5814700.
      Citations: 6     Fields:    Translation:AnimalsCells
    18. Hosoki K, Redding D, Itazawa T, Chakraborty A, Tapryal N, Qian S, Qi H, Aguilera-Aguirre L, Brasier AR, Phani VS, Hazra TK, Boldogh I, Sur S. Innate mechanism of pollen- and cat dander-induced oxidative stress and DNA damage in the airways. J Allergy Clin Immunol. 2017 11; 140(5):1436-1439.e5. PMID: 28583369.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    19. Hosoki K, Brasier AR, Kurosky A, Boldogh I, Sur S. Reply: Protease Plays a Role in Ragweed Pollen-Induced Neutrophil Recruitment and Epithelial Barrier Disruption. Am J Respir Cell Mol Biol. 2017 02; 56(2):272-273. PMID: 28145773; PMCID: PMC5359652.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    20. Patel TR, Sur S. IgE and eosinophils as therapeutic targets in asthma. Curr Opin Allergy Clin Immunol. 2017 Feb; 17(1):42-49. PMID: 27906698.
      Citations:    
    21. Hosoki K, Itazawa T, Boldogh I, Sur S. Neutrophil recruitment by allergens contribute to allergic sensitization and allergic inflammation. Curr Opin Allergy Clin Immunol. 2016 Feb; 16(1):45-50. PMID: 26694038; PMCID: PMC4941617.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    22. Hosoki K, Aguilera-Aguirre L, Brasier AR, Kurosky A, Boldogh I, Sur S. Facilitation of Allergic Sensitization and Allergic Airway Inflammation by Pollen-Induced Innate Neutrophil Recruitment. Am J Respir Cell Mol Biol. 2016 Jan; 54(1):81-90. PMID: 26086549; PMCID: PMC4742928.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    23. Hosoki K, Boldogh I, Aguilera-Aguirre L, Sun Q, Itazawa T, Hazra T, Brasier AR, Kurosky A, Sur S. Myeloid differentiation protein 2 facilitates pollen- and cat dander-induced innate and allergic airway inflammation. J Allergy Clin Immunol. 2016 05; 137(5):1506-1513.e2. PMID: 26586036; PMCID: PMC4860180.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    24. Chakraborty A, Wakamiya M, Venkova-Canova T, Pandita RK, Aguilera-Aguirre L, Sarker AH, Singh DK, Hosoki K, Wood TG, Sharma G, Cardenas V, Sarkar PS, Sur S, Pandita TK, Boldogh I, Hazra TK. Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation. J Biol Chem. 2015 Oct 09; 290(41):24636-48. PMID: 26245904; PMCID: PMC4598976.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    25. Aguilera-Aguirre L, Hosoki K, Bacsi A, Sur S, Hegde ML, Tian B, Saavedra-Molina A, Brasier AR, Ba X, Boldogh I, Rad?k Z. Whole transcriptome analysis reveals a role for OGG1-initiated DNA repair signaling in airway remodeling. Free Radic Biol Med. 2015 Dec; 89:20-33. PMID: 26187872; PMCID: PMC4924473.
      Citations: 17     Fields:    Translation:AnimalsCells
    26. Murai H, Okazaki S, Hayashi H, Kawakita A, Hosoki K, Yasutomi M, Sur S, Ohshima Y. Alternaria extract activates autophagy that induces IL-18 release from airway epithelial cells. Biochem Biophys Res Commun. 2015 Sep 04; 464(4):969-974. PMID: 26032499; PMCID: PMC4915742.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    27. Hosoki K, Ying S, Corrigan C, Qi H, Kurosky A, Jennings K, Sun Q, Boldogh I, Sur S. Analysis of a Panel of 48 Cytokines in BAL Fluids Specifically Identifies IL-8 Levels as the Only Cytokine that Distinguishes Controlled Asthma from Uncontrolled Asthma, and Correlates Inversely with FEV1. PLoS One. 2015; 10(5):e0126035. PMID: 26011707; PMCID: PMC4444276.
      Citations: 36     Fields:    Translation:HumansCells
    28. Hosoki K, Boldogh I, Sur S. Innate responses to pollen allergens. Curr Opin Allergy Clin Immunol. 2015 Feb; 15(1):79-88. PMID: 25546327; PMCID: PMC4361229.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    29. Ba X, Aguilera-Aguirre L, Sur S, Boldogh I. 8-Oxoguanine DNA glycosylase-1-driven DNA base excision repair: role in asthma pathogenesis. Curr Opin Allergy Clin Immunol. 2015 Feb; 15(1):89-97. PMID: 25486379; PMCID: PMC4364697.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    30. Aguilera-Aguirre L, Hosoki K, Bacsi A, Wood TG, Widen SG, Sur S, Ameredes BT, Saavedra-Molina A, Brasier AR, Ba X, Boldogh I, Rad?k Z. Whole transcriptome analysis reveals an 8-oxoguanine DNA glycosylase-1-driven DNA repair-dependent gene expression linked to essential biological processes. Free Radic Biol Med. 2015 Apr; 81:107-18. PMID: 25614460; PMCID: PMC4359954.
      Citations: 21     Fields:    Translation:AnimalsCells
    31. Aguilera-Aguirre L, Bacsi A, Radak Z, Hazra TK, Mitra S, Sur S, Brasier AR, Ba X, Boldogh I. Innate inflammation induced by the 8-oxoguanine DNA glycosylase-1-KRAS-NF-?B pathway. J Immunol. 2014 Nov 01; 193(9):4643-53. PMID: 25267977; PMCID: PMC4201976.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    32. Ba X, Aguilera-Aguirre L, Rashid QT, Bacsi A, Radak Z, Sur S, Hosoki K, Hegde ML, Boldogh I. The role of 8-oxoguanine DNA glycosylase-1 in inflammation. Int J Mol Sci. 2014 Sep 23; 15(9):16975-97. PMID: 25250913; PMCID: PMC4200771.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    33. Dahm PH, Richards JB, Karmouty-Quintana H, Cromar KR, Sur S, Price RE, Malik F, Spencer CY, Barreno RX, Hashmi SS, Blackburn MR, Haque IU, Johnston RA. Effect of antigen sensitization and challenge on oscillatory mechanics of the lung and pulmonary inflammation in obese carboxypeptidase E-deficient mice. Am J Physiol Regul Integr Comp Physiol. 2014 Sep 15; 307(6):R621-33. PMID: 25009214; PMCID: PMC4166760.
      Citations: 11     Fields:    Translation:Animals
    34. Luo J, Hosoki K, Bacsi A, Radak Z, Hegde ML, Sur S, Hazra TK, Brasier AR, Ba X, Boldogh I. 8-Oxoguanine DNA glycosylase-1-mediated DNA repair is associated with Rho GTPase activation and a-smooth muscle actin polymerization. Free Radic Biol Med. 2014 Aug; 73:430-8. PMID: 24681335; PMCID: PMC4156873.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    35. Sokol K, Sur S, Ameredes BT. Inhaled environmental allergens and toxicants as determinants of the asthma phenotype. Adv Exp Med Biol. 2014; 795:43-73. PMID: 24162902; PMCID: PMC9116436.
      Citations:    
    36. Yadav UC, Mishra R, Aguilera-Aguirre L, Sur S, Bolodgh I, Ramana KV, Srivatsava SK. Prevention of allergic rhinitis by aldose reductase inhibition in a murine model. Inflamm Allergy Drug Targets. 2013 Jun; 12(3):178-86. PMID: 23360251.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    37. Hajas G, Bacsi A, Aguilera-Aguirre L, Hegde ML, Tapas KH, Sur S, Radak Z, Ba X, Boldogh I. 8-Oxoguanine DNA glycosylase-1 links DNA repair to cellular signaling via the activation of the small GTPase Rac1. Free Radic Biol Med. 2013 Aug; 61:384-94. PMID: 23612479; PMCID: PMC3795866.
      Citations: 38     Fields:    Translation:AnimalsCells
    38. Bacsi A, Aguilera-Aguirre L, Szczesny B, Radak Z, Hazra TK, Sur S, Ba X, Boldogh I. Down-regulation of 8-oxoguanine DNA glycosylase 1 expression in the airway epithelium ameliorates allergic lung inflammation. DNA Repair (Amst). 2013 Jan 01; 12(1):18-26. PMID: 23127499; PMCID: PMC3678389.
      Citations: 40     Fields:    Translation:AnimalsCells
    39. Boldogh I, Hajas G, Aguilera-Aguirre L, Hegde ML, Radak Z, Bacsi A, Sur S, Hazra TK, Mitra S. Activation of ras signaling pathway by 8-oxoguanine DNA glycosylase bound to its excision product, 8-oxoguanine. J Biol Chem. 2012 Jun 15; 287(25):20769-73. PMID: 22568941; PMCID: PMC3375501.
      Citations: 59     Fields:    Translation:HumansCells
    40. Murai H, Qi H, Choudhury B, Wild J, Dharajiya N, Vaidya S, Kalita A, Bacsi A, Corry D, Kurosky A, Brasier A, Boldogh I, Sur S. Alternaria-induced release of IL-18 from damaged airway epithelial cells: an NF-?B dependent mechanism of Th2 differentiation? PLoS One. 2012; 7(2):e30280. PMID: 22347372; PMCID: PMC3274547.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    41. Hajas G, Bacsi A, Aguilerra-Aguirre L, German P, Radak Z, Sur S, Hazra TK, Boldogh I. Biochemical identification of a hydroperoxide derivative of the free 8-oxo-7,8-dihydroguanine base. Free Radic Biol Med. 2012 Feb 15; 52(4):749-56. PMID: 22198182; PMCID: PMC3267897.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    42. Saavedra MC, Sur S. Down regulation of the high-affinity IgE receptor associated with successful treatment of chronic idiopathic urticaria with omalizumab. Clin Mol Allergy. 2011 Jan 19; 9(1):2. PMID: 21247438; PMCID: PMC3031269.
      Citations:    
    43. Dharajiya N, Vaidya S, Sinha M, Luxon B, Boldogh I, Sur S. Allergen challenge induces Ifng dependent GTPases in the lungs as part of a Th1 transcriptome response in a murine model of allergic asthma. PLoS One. 2009 Dec 21; 4(12):e8172. PMID: 20027288; PMCID: PMC2791840.
      Citations: 7     Fields:    Translation:AnimalsCells
    44. Aguilera-Aguirre L, Bacsi A, Saavedra-Molina A, Kurosky A, Sur S, Boldogh I. Mitochondrial dysfunction increases allergic airway inflammation. J Immunol. 2009 Oct 15; 183(8):5379-87. PMID: 19786549; PMCID: PMC3028535.
      Citations: 108     Fields:    Translation:HumansAnimalsCells
    45. Yadav UC, Naura AS, Aguilera-Aguirre L, Ramana KV, Boldogh I, Sur S, Boulares HA, Srivastava SK. Aldose reductase inhibition suppresses the expression of Th2 cytokines and airway inflammation in ovalbumin-induced asthma in mice. J Immunol. 2009 Oct 01; 183(7):4723-32. PMID: 19752229; PMCID: PMC4167870.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    46. Chodaczek G, Bacsi A, Dharajiya N, Sur S, Hazra TK, Boldogh I. Ragweed pollen-mediated IgE-independent release of biogenic amines from mast cells via induction of mitochondrial dysfunction. Mol Immunol. 2009 Aug; 46(13):2505-14. PMID: 19501909; PMCID: PMC2713802.
      Citations: 17     Fields:    Translation:AnimalsCells
    47. Goswami S, Angkasekwinai P, Shan M, Greenlee KJ, Barranco WT, Polikepahad S, Seryshev A, Song LZ, Redding D, Singh B, Sur S, Woodruff P, Dong C, Corry DB, Kheradmand F. Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma. Nat Immunol. 2009 May; 10(5):496-503. PMID: 19329997; PMCID: PMC5298936.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    48. Dharajiya N, Boldogh I, Cardenas V, Sur S. Role of pollen NAD(P)H oxidase in allergic inflammation. Curr Opin Allergy Clin Immunol. 2008 Feb; 8(1):57-62. PMID: 18188019; PMCID: PMC3079523.
      Citations:    
    49. Dharajiya N, Choudhury BK, Bacsi A, Boldogh I, Alam R, Sur S. Inhibiting pollen reduced nicotinamide adenine dinucleotide phosphate oxidase-induced signal by intrapulmonary administration of antioxidants blocks allergic airway inflammation. J Allergy Clin Immunol. 2007 Mar; 119(3):646-53. PMID: 17336614; PMCID: PMC3042252.
      Citations: 23     Fields:    Translation:Animals
    50. Chodaczek G, Saavedra-Molina A, Bacsi A, Kruzel ML, Sur S, Boldogh I. Iron-mediated dismutation of superoxide anion augments antigen-induced allergic inflammation: effect of lactoferrin. Postepy Hig Med Dosw (Online). 2007; 61:268-76. PMID: 17507875.
      Citations: 12     Fields:    Translation:AnimalsCells
    51. Bacsi A, Choudhury BK, Dharajiya N, Sur S, Boldogh I. Subpollen particles: carriers of allergenic proteins and oxidases. J Allergy Clin Immunol. 2006 Oct; 118(4):844-50. PMID: 17030236; PMCID: PMC3079542.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    52. Kruzel ML, Bacsi A, Choudhury B, Sur S, Boldogh I. Lactoferrin decreases pollen antigen-induced allergic airway inflammation in a murine model of asthma. Immunology. 2006 Oct; 119(2):159-66. PMID: 16800860; PMCID: PMC1782357.
      Citations: 33     Fields:    Translation:AnimalsCells
    53. Bacsi A, Dharajiya N, Choudhury BK, Sur S, Boldogh I. Effect of pollen-mediated oxidative stress on immediate hypersensitivity reactions and late-phase inflammation in allergic conjunctivitis. J Allergy Clin Immunol. 2005 Oct; 116(4):836-43. PMID: 16210058; PMCID: PMC3030477.
      Citations:    
    54. Boldogh I, Bacsi A, Choudhury BK, Dharajiya N, Alam R, Hazra TK, Mitra S, Goldblum RM, Sur S. ROS generated by pollen NADPH oxidase provide a signal that augments antigen-induced allergic airway inflammation. J Clin Invest. 2005 Aug; 115(8):2169-79. PMID: 16075057; PMCID: PMC1180538.
      Citations: 135     Fields:    Translation:HumansAnimalsCells
    55. Bloebaum RM, Grant JA, Sur S. Immunomodulation: the future of allergy and asthma treatment. Curr Opin Allergy Clin Immunol. 2004 Feb; 4(1):63-7. PMID: 15090922.
      Citations:    
    56. Gorska MM, Stafford SJ, Cen O, Sur S, Alam R. Unc119, a novel activator of Lck/Fyn, is essential for T cell activation. J Exp Med. 2004 Feb 02; 199(3):369-79. PMID: 14757743; PMCID: PMC2211793.
      Citations:    
    57. Leonard P, Sur S. Interleukin-12: potential role in asthma therapy. BioDrugs. 2003; 17(1):1-7. PMID: 12534316.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    58. Leonard PA, Woodside KJ, Gugliuzza KK, Sur S, Daller JA. Safe administration of a humanized murine antibody after anaphylaxis to a chimeric murine antibody. Transplantation. 2002 Dec 27; 74(12):1697-700. PMID: 12499883.
      Citations: 3     Fields:    Translation:HumansAnimals
    59. Choudhury BK, Wild JS, Alam R, Klinman DM, Boldogh I, Dharajiya N, Mileski WJ, Sur S. In vivo role of p38 mitogen-activated protein kinase in mediating the anti-inflammatory effects of CpG oligodeoxynucleotide in murine asthma. J Immunol. 2002 Nov 15; 169(10):5955-61. PMID: 12421981.
      Citations: 14     Fields:    Translation:AnimalsCells
    60. Leonard P, Sur S. Asthma: future directions. Med Clin North Am. 2002 Sep; 86(5):1131-56. PMID: 12428548.
      Citations:    Fields:    Translation:Humans
    61. Stafford S, Lowell C, Sur S, Alam R. Lyn tyrosine kinase is important for IL-5-stimulated eosinophil differentiation. J Immunol. 2002 Feb 15; 168(4):1978-83. PMID: 11823534.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    62. Michalec L, Choudhury BK, Postlethwait E, Wild JS, Alam R, Lett-Brown M, Sur S. CCL7 and CXCL10 orchestrate oxidative stress-induced neutrophilic lung inflammation. J Immunol. 2002 Jan 15; 168(2):846-52. PMID: 11777981.
      Citations: 73     Fields:    Translation:AnimalsCells
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