Xeroderma Pigmentosum Group A Protein
"Xeroderma Pigmentosum Group A Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ZINC FINGER MOTIF protein that recognizes and interacts with damaged DNA. It is a DNA-binding protein that plays an essential role in NUCLEOTIDE EXCISION REPAIR. Mutations in this protein are associated with the most severe form of XERODERMA PIGMENTOSUM.
| Descriptor ID |
D051760
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| MeSH Number(s) |
D12.776.157.687.875 D12.776.260.975 D12.776.660.720.875
|
| Concept/Terms |
Xeroderma Pigmentosum Group A Protein- Xeroderma Pigmentosum Group A Protein
- XPA Nucleotide Excision Repair Protein
- Xeroderma Pigmentosum-A Protein
- Xeroderma Pigmentosum A Protein
- XPA Repair Protein
- Xeroderma Pigmentosum Group A Complementing Protein
|
Below are MeSH descriptors whose meaning is more general than "Xeroderma Pigmentosum Group A Protein".
Below are MeSH descriptors whose meaning is more specific than "Xeroderma Pigmentosum Group A Protein".
This graph shows the total number of publications written about "Xeroderma Pigmentosum Group A Protein" by people in this website by year, and whether "Xeroderma Pigmentosum Group A Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Xeroderma Pigmentosum Group A Protein" by people in Profiles.
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Associations between expression levels of nucleotide excision repair proteins in lymphoblastoid cells and risk of squamous cell carcinoma of the head and neck. Mol Carcinog. 2018 06; 57(6):784-793.
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Variants in nucleotide excision repair core genes and susceptibility to recurrence of squamous cell carcinoma of the oropharynx. Int J Cancer. 2013 Aug 01; 133(3):695-704.
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Xpa deficiency reduces CAG trinucleotide repeat instability in neuronal tissues in a mouse model of SCA1. Hum Mol Genet. 2011 Dec 15; 20(24):4822-30.
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The oncogenic phosphatase WIP1 negatively regulates nucleotide excision repair. DNA Repair (Amst). 2010 Jul 01; 9(7):813-23.
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Recruitment of fanconi anemia and breast cancer proteins to DNA damage sites is differentially governed by replication. Mol Cell. 2009 Sep 11; 35(5):716-23.
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Elevation of XPA protein level in testis tumor cells without increasing resistance to cisplatin or UV radiation. Mol Carcinog. 2008 Aug; 47(8):580-6.
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Moving toward individualized therapy based on NER polymorphisms that predict platinum sensitivity in ovarian cancer patients. Gynecol Oncol. 2007 Oct; 107(1 Suppl 1):S223-9.
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XPA protein as a limiting factor for nucleotide excision repair and UV sensitivity in human cells. DNA Repair (Amst). 2006 May 10; 5(5):641-8.
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Nucleotide excision repair gene polymorphisms and recurrence after treatment for superficial bladder cancer. Clin Cancer Res. 2005 Feb 15; 11(4):1408-15.
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Reduced levels of XPA, ERCC1 and XPF DNA repair proteins in testis tumor cell lines. Int J Cancer. 2004 Jun 20; 110(3):352-61.