TCF Transcription Factors
"TCF Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of DNA-binding proteins that are primarily expressed in T-LYMPHOCYTES. They interact with BETA CATENIN and serve as transcriptional activators and repressors in a variety of developmental processes.
| Descriptor ID |
D051820
|
| MeSH Number(s) |
D12.776.260.730 D12.776.660.235.400.800 D12.776.664.235.400.800 D12.776.930.875
|
| Concept/Terms |
TCF Transcription Factors- TCF Transcription Factors
- Transcription Factors, TCF
- Lymphoid Enhancer Factors
- T-Cell Factors
- T Cell Factors
- LEF Transcription Factors
- Transcription Factors, LEF
|
Below are MeSH descriptors whose meaning is more general than "TCF Transcription Factors".
Below are MeSH descriptors whose meaning is more specific than "TCF Transcription Factors".
This graph shows the total number of publications written about "TCF Transcription Factors" by people in this website by year, and whether "TCF Transcription Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 4 | 1 | 5 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 1 | 2 |
| 2017 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "TCF Transcription Factors" by people in Profiles.
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Yap and Taz promote osteogenesis and prevent chondrogenesis in neural crest cells in vitro and in vivo. Sci Signal. 2022 10 25; 15(757):eabn9009.
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SPDEF Induces Quiescence of Colorectal Cancer Cells by?Changing the Transcriptional Targets of ?-catenin. Gastroenterology. 2017 07; 153(1):205-218.e8.
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Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer. Cancer Cell. 2013 Mar 18; 23(3):316-31.
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Inhibition of Wnt signaling by cucurbitacin B in breast cancer cells: reduction of Wnt-associated proteins and reduced translocation of galectin-3-mediated ?-catenin to the nucleus. J Cell Biochem. 2012 Jan; 113(1):49-60.
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Transcription factor 7-like 2 (TCF7L2) polymorphism and context-specific risk of impaired fasting glucose in African American and Caucasian adults: the atherosclerosis risk in communities (ARIC) study. Diabetes Metab Res Rev. 2010 Jul; 26(5):371-7.
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Diabetes genes and prostate cancer in the Atherosclerosis Risk in Communities study. Cancer Epidemiol Biomarkers Prev. 2010 Feb; 19(2):558-65.
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TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action. Diabetes. 2010 Feb; 59(2):479-85.
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Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia. Nat Genet. 2009 Oct; 41(10):1068-75.
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WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis. Cell. 2009 Jul 10; 138(1):51-62.
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beta-Catenin stabilization imparts crypt progenitor phenotype to hyperproliferating colonic epithelia. Exp Cell Res. 2009 Jan 01; 315(1):97-109.