Lymphoid Enhancer-Binding Factor 1
"Lymphoid Enhancer-Binding Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A T-cell factor that plays an essential role in EMBRYONIC DEVELOPMENT.
| Descriptor ID |
D051821
|
| MeSH Number(s) |
D12.776.260.730.500 D12.776.660.235.400.800.500 D12.776.664.235.400.800.500 D12.776.930.875.500
|
| Concept/Terms |
Lymphoid Enhancer-Binding Factor 1- Lymphoid Enhancer-Binding Factor 1
- Lymphoid Enhancer Binding Factor 1
- LEF-1 Transcription Factor
- LEF 1 Transcription Factor
- Transcription Factor, LEF-1
- T Cell-Specific Transcription Factor 1-alpha
- T Cell Specific Transcription Factor 1 alpha
|
Below are MeSH descriptors whose meaning is more general than "Lymphoid Enhancer-Binding Factor 1".
Below are MeSH descriptors whose meaning is more specific than "Lymphoid Enhancer-Binding Factor 1".
This graph shows the total number of publications written about "Lymphoid Enhancer-Binding Factor 1" by people in this website by year, and whether "Lymphoid Enhancer-Binding Factor 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
| 2013 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 2 | 2 |
| 2020 | 2 | 0 | 2 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Lymphoid Enhancer-Binding Factor 1" by people in Profiles.
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PRAME and LEF1 in Combined Deep Penetrating Nevus and Combined Blue Nevus: Utility and Pitfalls. Am J Dermatopathol. 2023 08 01; 45(8):549-556.
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LEF1 Drives a Central Memory Program and Supports Antitumor Activity of Natural Killer T Cells. Cancer Immunol Res. 2023 02 03; 11(2):171-183.
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Lymphoid enhancer binding factor 1 (LEF1) expression is significantly higher in Hodgkin lymphoma associated with Richter syndrome relative to de novo classic Hodgkin lymphoma. Ann Diagn Pathol. 2020 Dec; 49:151636.
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Redundant and additive functions of the four Lef/Tcf transcription factors in lung epithelial progenitors. Proc Natl Acad Sci U S A. 2020 06 02; 117(22):12182-12191.
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Classical Hodgkin lymphoma arising in a patient with chronic lymphocytic leukemia (Richter syndrome). Blood. 2017 11 09; 130(19):2151.
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Lef1-dependent hypothalamic neurogenesis inhibits anxiety. PLoS Biol. 2017 Aug; 15(8):e2002257.
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SPDEF Induces Quiescence of Colorectal Cancer Cells by?Changing the Transcriptional Targets of ?-catenin. Gastroenterology. 2017 07; 153(1):205-218.e8.
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High LEF1 expression predicts adverse prognosis in chronic lymphocytic leukemia and may be targeted by ethacrynic acid. Oncotarget. 2016 Apr 19; 7(16):21631-43.
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Eyelid sebaceous carcinoma: a novel mutation in lymphoid enhancer-binding factor-1. Br J Dermatol. 2015 Sep; 173(3):811-4.
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Brief report: Oct4 and canonical Wnt signaling regulate the cardiac lineage factor Mesp1 through a Tcf/Lef-Oct4 composite element. Stem Cells. 2013 Jun; 31(6):1213-7.