T Cell Transcription Factor 1
"T Cell Transcription Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A TCF transcription factor that was originally identified as a DNA-binding protein that interacts with the enhancers of T-CELL RECEPTOR ALPHA GENES. It plays a role in T-LYMPHOCYTE development.
| Descriptor ID |
D051822
|
| MeSH Number(s) |
D12.776.260.730.750 D12.776.660.235.400.800.750 D12.776.664.235.400.800.750 D12.776.930.875.750
|
| Concept/Terms |
T Cell Transcription Factor 1- T Cell Transcription Factor 1
- TCF-1 Transcription Factor
- TCF 1 Transcription Factor
- Transcription Factor, TCF-1
- Transcription Factor 7
- T Cell Factor 1
|
Below are MeSH descriptors whose meaning is more general than "T Cell Transcription Factor 1".
Below are MeSH descriptors whose meaning is more specific than "T Cell Transcription Factor 1".
This graph shows the total number of publications written about "T Cell Transcription Factor 1" by people in this website by year, and whether "T Cell Transcription Factor 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "T Cell Transcription Factor 1" by people in Profiles.
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PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program. Nature. 2022 10; 610(7930):173-181.
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Tertiary lymphoid structures improve immunotherapy and survival in melanoma. Nature. 2020 01; 577(7791):561-565.
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Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ. Nat Commun. 2019 09 13; 10(1):4182.
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USP21 deubiquitinase promotes pancreas cancer cell stemness via Wnt pathway activation. Genes Dev. 2019 10 01; 33(19-20):1361-1366.
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Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma. Cell. 2018 11 01; 175(4):998-1013.e20.
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The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex. Nat Immunol. 2014 May; 15(5):457-64.
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Genetic modification of T cells with IL-21 enhances antigen presentation and generation of central memory tumor-specific cytotoxic T-lymphocytes. J Immunother. 2009 Sep; 32(7):726-36.
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P68 RNA helicase mediates PDGF-induced epithelial mesenchymal transition by displacing Axin from beta-catenin. Cell. 2006 Oct 06; 127(1):139-55.