T Cell Transcription Factor 1
"T Cell Transcription Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A TCF transcription factor that was originally identified as a DNA-binding protein that interacts with the enhancers of T-CELL RECEPTOR ALPHA GENES. It plays a role in T-LYMPHOCYTE development.
| Descriptor ID |
D051822
|
| MeSH Number(s) |
D12.776.260.730.750 D12.776.660.235.400.800.750 D12.776.664.235.400.800.750 D12.776.930.875.750
|
| Concept/Terms |
T Cell Transcription Factor 1- T Cell Transcription Factor 1
- TCF-1 Transcription Factor
- TCF 1 Transcription Factor
- Transcription Factor, TCF-1
- Transcription Factor 7
- T Cell Factor 1
|
Below are MeSH descriptors whose meaning is more general than "T Cell Transcription Factor 1".
Below are MeSH descriptors whose meaning is more specific than "T Cell Transcription Factor 1".
This graph shows the total number of publications written about "T Cell Transcription Factor 1" by people in this website by year, and whether "T Cell Transcription Factor 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "T Cell Transcription Factor 1" by people in Profiles.
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Transcription factor TCF1 binds to ROR?t and orchestrates a regulatory network that determines homeostatic Th17 cell state. Immunity. 2024 11 12; 57(11):2565-2582.e6.
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PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program. Nature. 2022 10; 610(7930):173-181.
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Long Noncoding RNA NHEG1 Drives ?-Catenin Transactivation and Neuroblastoma Progression through Interacting with DDX5. Mol Ther. 2020 03 04; 28(3):946-962.
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Identification of a novel mechanism of action of fingolimod (FTY720) on human effector T cell function through TCF-1 upregulation. J Neuroinflammation. 2015 Dec 30; 12:245.
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Genetic modification of T cells with IL-21 enhances antigen presentation and generation of central memory tumor-specific cytotoxic T-lymphocytes. J Immunother. 2009 Sep; 32(7):726-36.
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P68 RNA helicase mediates PDGF-induced epithelial mesenchymal transition by displacing Axin from beta-catenin. Cell. 2006 Oct 06; 127(1):139-55.
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Molecular characterization of a zebrafish TCF ETS-domain transcription factor. Oncogene. 1999 Dec 23; 18(56):7985-93.