"Sirtuin 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sirtuin family member found primarily in MITOCHONDRIA. It is a multifunctional enzyme that contains a NAD-dependent deacetylase activity that is specific for HISTONES and a mono-ADP-ribosyltransferase activity.
| Descriptor ID |
D056566
|
| MeSH Number(s) |
D08.811.277.087.520.200.650.600 D08.811.913.400.725.115.961.600 D12.776.476.900.600 D12.776.575.875
|
| Concept/Terms |
Sirtuin 3- Sirtuin 3
- Silent Mating Type Information Regulation 2 Homolog 3
|
Below are MeSH descriptors whose meaning is more general than "Sirtuin 3".
Below are MeSH descriptors whose meaning is more specific than "Sirtuin 3".
This graph shows the total number of publications written about "Sirtuin 3" by people in this website by year, and whether "Sirtuin 3" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 3 | 0 | 3 |
| 2010 | 2 | 0 | 2 |
| 2011 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 2 | 1 | 3 |
| 2019 | 2 | 0 | 2 |
| 2020 | 2 | 0 | 2 |
| 2021 | 3 | 0 | 3 |
| 2022 | 2 | 0 | 2 |
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Below are the most recent publications written about "Sirtuin 3" by people in Profiles.
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Mitochondrial Sirtuin-3 (SIRT3) Prevents Doxorubicin-Induced Dilated Cardiomyopathy by Modulating Protein Acetylation and Oxidative Stress. Circ Heart Fail. 2022 05; 15(5):e008547.
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The Role of Palmitoleic Acid in Regulating Hepatic Gluconeogenesis through SIRT3 in Obese Mice. Nutrients. 2022 Apr 01; 14(7).
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Berberine remodels adipose tissue to attenuate metabolic disorders by activating sirtuin 3. Acta Pharmacol Sin. 2022 May; 43(5):1285-1298.
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SIRT3 is required for liver regeneration but not for the beneficial effect of nicotinamide riboside. JCI Insight. 2021 04 08; 6(7).
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Sirtuin-3 mediates sex differences in kidney ischemia-reperfusion injury. Transl Res. 2021 09; 235:15-31.
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Transcriptional Repression of SIRT3 Potentiates Mitochondrial Aconitase Activation to Drive Aggressive Prostate Cancer to the Bone. Cancer Res. 2021 01 01; 81(1):50-63.
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SIRT3 Acts as a Positive Autophagy Regulator to Promote Lipid Mobilization in Adipocytes via Activating AMPK. Int J Mol Sci. 2020 Jan 07; 21(2).
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A novel metadherin?7 splice variant enhances triple negative breast cancer aggressiveness by modulating mitochondrial function via NF?B-SIRT3 axis. Oncogene. 2020 03; 39(10):2088-2102.
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SIRT3 promotes lipophagy and chaperon-mediated autophagy to protect hepatocytes against lipotoxicity. Cell Death Differ. 2020 01; 27(1):329-344.
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SIRT3 controls brown fat thermogenesis by deacetylation regulation of pathways upstream of UCP1. Mol Metab. 2019 07; 25:35-49.