Proto-Oncogene Proteins c-myc
"Proto-Oncogene Proteins c-myc" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Basic helix-loop-helix transcription factors encoded by the c-myc genes. They are normally involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Elevated and deregulated (constitutive) expression of c-myc proteins can cause tumorigenesis.
| Descriptor ID |
D016271
|
| MeSH Number(s) |
D12.776.260.103.813 D12.776.624.664.700.189 D12.776.660.765 D12.776.930.125.813
|
| Concept/Terms |
Proto-Oncogene Proteins c-myc- Proto-Oncogene Proteins c-myc
- Proto Oncogene Proteins c myc
- myc Proto-Oncogene Product p62
- myc Proto Oncogene Product p62
- Proto-Oncogene Proteins myc
- Proteins myc, Proto-Oncogene
- Proto Oncogene Proteins myc
- myc, Proto-Oncogene Proteins
- p62 c-myc
- p62 c myc
- p62(c-myc)
- Proto-Oncogene Products c-myc
- Proto Oncogene Products c myc
- c-myc Proteins
- c myc Proteins
- myc Proto-Oncogene Proteins
- Proto-Oncogene Proteins, myc
- myc Proto Oncogene Proteins
|
Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-myc".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-myc".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-myc" by people in this website by year, and whether "Proto-Oncogene Proteins c-myc" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 0 | 2 |
| 1995 | 5 | 2 | 7 |
| 1996 | 2 | 0 | 2 |
| 1997 | 2 | 2 | 4 |
| 1998 | 3 | 3 | 6 |
| 1999 | 1 | 1 | 2 |
| 2000 | 6 | 6 | 12 |
| 2001 | 2 | 4 | 6 |
| 2002 | 5 | 3 | 8 |
| 2003 | 3 | 8 | 11 |
| 2004 | 5 | 2 | 7 |
| 2005 | 5 | 4 | 9 |
| 2006 | 7 | 7 | 14 |
| 2007 | 6 | 2 | 8 |
| 2008 | 4 | 4 | 8 |
| 2009 | 2 | 7 | 9 |
| 2010 | 5 | 9 | 14 |
| 2011 | 11 | 5 | 16 |
| 2012 | 11 | 12 | 23 |
| 2013 | 7 | 9 | 16 |
| 2014 | 6 | 5 | 11 |
| 2015 | 17 | 13 | 30 |
| 2016 | 17 | 17 | 34 |
| 2017 | 8 | 8 | 16 |
| 2018 | 15 | 5 | 20 |
| 2019 | 5 | 3 | 8 |
| 2020 | 13 | 4 | 17 |
| 2021 | 10 | 10 | 20 |
| 2022 | 5 | 5 | 10 |
| 2023 | 1 | 9 | 10 |
| 2024 | 4 | 4 | 8 |
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Below are the most recent publications written about "Proto-Oncogene Proteins c-myc" by people in Profiles.
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The SAGA acetyltransferase module is required for the maintenance of MAF and MYC oncogenic gene expression programs in multiple myeloma. Genes Dev. 2024 Sep 19; 38(15-16):738-754.
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MYC Induces Oncogenic Stress through RNA Decay and Ribonucleotide Catabolism in Breast Cancer. Cancer Discov. 2024 Sep 04; 14(9):1699-1716.
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Androgen receptor monomers and dimers regulate opposing biological processes in prostate cancer cells. Nat Commun. 2024 Sep 03; 15(1):7675.
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Prognostic Impact of Notch1 Intracellular Domain, P63, and c-MYC in Lacrimal Gland Adenoid Cystic Carcinoma. Invest Ophthalmol Vis Sci. 2024 Sep 03; 65(11):4.
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Prognostic stratification in DLBCL patients with aberrant MYC gene. Br J Haematol. 2024 Nov; 205(5):1782-1793.
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The DNA methylome of pediatric brain tumors appears shaped by structural variation and predicts survival. Nat Commun. 2024 Aug 08; 15(1):6775.
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Low NDRG2, regulated by the MYC/MIZ-1 complex and methylation, predicts poor outcomes in DLBCL patients. Ann Hematol. 2024 Aug; 103(8):2877-2892.
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Orthogonal proteogenomic analysis identifies the druggable PA2G4-MYC axis in 3q26 AML. Nat Commun. 2024 Jun 04; 15(1):4739.
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Selective CDK7 Inhibition Suppresses Cell Cycle Progression and MYC Signaling While Enhancing Apoptosis in Therapy-resistant Estrogen Receptor-positive Breast Cancer. Clin Cancer Res. 2024 May 01; 30(9):1889-1905.
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The synergy of the XPO1 inhibitors combined with the BET inhibitor INCB057643 in high-grade B-cell lymphoma via downregulation of MYC expression. Sci Rep. 2023 10 29; 13(1):18554.