"Proto-Oncogene Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are involved in the regulation or differentiation of cell growth. They often have protein kinase activity.
| Descriptor ID |
D011518
|
| MeSH Number(s) |
D12.776.624.664.700
|
| Concept/Terms |
Proto-Oncogene Proteins- Proto-Oncogene Proteins
- Proto Oncogene Proteins
- Proto-Oncogene Products, Cellular
- Cellular Proto-Oncogene Products
- Proto Oncogene Products, Cellular
- Proto Oncogene Proteins, Cellular
- c-onc Proteins
- c onc Proteins
- Cellular Proto-Oncogene Proteins
- Cellular Proto Oncogene Proteins
- Proto-Oncogene Proteins, Cellular
|
Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins".
This graph shows the total number of publications written about "Proto-Oncogene Proteins" by people in this website by year, and whether "Proto-Oncogene Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 6 | 1 | 7 |
| 1996 | 8 | 7 | 15 |
| 1997 | 7 | 4 | 11 |
| 1998 | 12 | 4 | 16 |
| 1999 | 10 | 4 | 14 |
| 2000 | 6 | 6 | 12 |
| 2001 | 7 | 7 | 14 |
| 2002 | 12 | 12 | 24 |
| 2003 | 11 | 8 | 19 |
| 2004 | 16 | 11 | 27 |
| 2005 | 10 | 9 | 19 |
| 2006 | 6 | 2 | 8 |
| 2007 | 3 | 5 | 8 |
| 2008 | 4 | 3 | 7 |
| 2009 | 6 | 6 | 12 |
| 2010 | 4 | 2 | 6 |
| 2011 | 9 | 5 | 14 |
| 2012 | 3 | 4 | 7 |
| 2013 | 6 | 10 | 16 |
| 2014 | 7 | 7 | 14 |
| 2015 | 10 | 3 | 13 |
| 2016 | 6 | 3 | 9 |
| 2017 | 9 | 1 | 10 |
| 2018 | 7 | 3 | 10 |
| 2019 | 8 | 3 | 11 |
| 2020 | 7 | 4 | 11 |
| 2021 | 8 | 2 | 10 |
| 2022 | 0 | 6 | 6 |
| 2023 | 0 | 2 | 2 |
| 2024 | 5 | 5 | 10 |
| 2025 | 1 | 1 | 2 |
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Below are the most recent publications written about "Proto-Oncogene Proteins" by people in Profiles.
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Guanine nucleotide biosynthesis blockade impairs MLL complex formation and sensitizes leukemias to menin inhibition. Nat Commun. 2025 Mar 18; 16(1):2641.
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ERK activation dynamics in maturing oocyte controls embryonic nuclear divisions in Caenorhabditis elegans. Cell Rep. 2025 01 28; 44(1):115157.
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PRDM16 Enhances Osteoblastogenic RUNX2 via Canonical WNT10b/?-CATENIN Pathway in Testosterone-Treated Hypogonadal Men. Biomolecules. 2025 Jan 08; 15(1).
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Pharmacologic Blockade of a Pioneer Transcription Factor. Cancer Res. 2024 Dec 16; 84(24):4124-4125.
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The DNA demethylase TET1 modifies the impact of maternal folic acid status on embryonic brain development. EMBO Rep. 2025 Jan; 26(1):175-199.
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MLL oncoprotein levels influence leukemia lineage identities. Nat Commun. 2024 10 29; 15(1):9341.
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Biologic and Clinical Analysis of Childhood Gamma Delta T-ALL Identifies LMO2/STAG2 Rearrangements as Extremely High Risk. Cancer Discov. 2024 Oct 04; 14(10):1838-1859.
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Can Ruxolitinib Crash TET2- and IDH2-Driven Clonal Hematopoiesis? Cancer Discov. 2024 Oct 04; 14(10):1768-1770.
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ASXL1/TET2 genotype-based risk stratification outperforms ASXL1 mutational impact and is independent of mutant variant allele fractions in chronic myelomonocytic leukemia. Haematologica. 2024 Oct 01; 109(10):3419-3425.
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Role of HIF-1a-Activated IL-22/IL-22R1/Bmi1 Signaling Modulates the Self-Renewal of Cardiac Stem Cells in Acute Myocardial Ischemia. Stem Cell Rev Rep. 2024 Nov; 20(8):2194-2214.