"Stathmin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitous phosphoprotein that serves as an intracellular substrate for a variety of SIGNAL TRANSDUCTION PATHWAYS. PHOSPHORYLATION of stathmin occurs during CELL CYCLE progression, and stathmin functions as a microtubule-destabilizing protein that promotes MICROTUBULE depolymerization during INTERPHASE and late MITOSIS. Stathmin is expressed at very high levels in a variety of human CANCERS.
| Descriptor ID |
D050777
|
| MeSH Number(s) |
D12.776.220.600.450.480 D12.776.624.664.700.957 D12.776.744.772
|
| Concept/Terms |
Stathmin- Stathmin
- Leukemia-Associated Phosphoprotein p18
- Leukemia Associated Phosphoprotein p18
- p18, Leukemia-Associated Phosphoprotein
- Metablastin
- Prosolin
- Op18 Phosphoprotein
- Phosphoprotein, Op18
- Phosphoprotein p18
- p18, Phosphoprotein
- Phosphoprotein p19
- p19, Phosphoprotein
- Lap18 Protein
- Oncoprotein 18
|
Below are MeSH descriptors whose meaning is more general than "Stathmin".
Below are MeSH descriptors whose meaning is more specific than "Stathmin".
This graph shows the total number of publications written about "Stathmin" by people in this website by year, and whether "Stathmin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Stathmin" by people in Profiles.
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Epstein-Barr virus-encoded miR-BART6-3p inhibits cancer cell proliferation through the LOC553103-STMN1 axis. FASEB J. 2020 06; 34(6):8012-8027.
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p27/Kip1 functions as a tumor suppressor and oncoprotein in osteosarcoma. Sci Rep. 2019 04 16; 9(1):6161.
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Functional proteomics characterization of residual triple-negative breast cancer after standard neoadjuvant chemotherapy. Ann Oncol. 2013 Oct; 24(10):2522-2526.
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Bisphosphorylated PEA-15 sensitizes ovarian cancer cells to paclitaxel by impairing the microtubule-destabilizing effect of SCLIP. Mol Cancer Ther. 2013 Jun; 12(6):1099-111.
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Silencing kinase-interacting stathmin gene enhances erlotinib sensitivity by inhibiting Ser?? p27 phosphorylation in epidermal growth factor receptor-expressing breast cancer. Mol Cancer Ther. 2010 Nov; 9(11):3090-9.
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Myoblast-derived neuronal cells form glutamatergic neurons in the mouse cerebellum. Stem Cells. 2010 Oct; 28(10):1839-47.
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Stathmin activity influences sarcoma cell shape, motility, and metastatic potential. Mol Biol Cell. 2008 May; 19(5):2003-13.
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Identification of cJun-responsive genes in Rat-1a cells using multiple techniques: increased expression of stathmin is necessary for cJun-mediated anchorage-independent growth. Oncogene. 2003 May 08; 22(18):2710-22.
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Elevated levels of microtubule destabilizing factors in a Taxol-resistant/dependent A549 cell line with an alpha-tubulin mutation. Cancer Res. 2003 Mar 15; 63(6):1207-13.
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Overexpression of oncoprotein 18 correlates with poor differentiation in lung adenocarcinomas. Mol Cell Proteomics. 2003 Feb; 2(2):107-16.