Proto-Oncogene Proteins pp60(c-src)
"Proto-Oncogene Proteins pp60(c-src)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane-associated tyrosine-specific kinases encoded by the c-src genes. They have an important role in cellular growth control. Truncation of carboxy-terminal residues in pp60(c-src) leads to PP60(V-SRC) which has the ability to transform cells. This kinase pp60 c-src should not be confused with csk, also known as c-src kinase.
| Descriptor ID |
D016392
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| MeSH Number(s) |
D08.811.913.696.620.682.725.800.630 D12.776.624.664.700.202
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| Concept/Terms |
Proto-Oncogene Proteins pp60(c-src)- Proto-Oncogene Proteins pp60(c-src)
- Phosphoprotein pp60(c-src)
- pp60 c-src
- c-src, pp60
- pp60 c src
- pp60(c-src)
- Proto-Oncogene Protein src
- Protein src, Proto-Oncogene
- Proto Oncogene Protein src
- src Proto-Oncogene Product
- Proto-Oncogene Product, src
- src Proto Oncogene Product
- src Proto-Oncogene Protein pp60
- src Proto Oncogene Protein pp60
- c-src Protein pp60
- Protein pp60, c-src
- c src Protein pp60
- pp60, c-src Protein
- Proto-Oncogene Protein pp60(c-src)
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins pp60(c-src)".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins pp60(c-src)".
This graph shows the total number of publications written about "Proto-Oncogene Proteins pp60(c-src)" by people in this website by year, and whether "Proto-Oncogene Proteins pp60(c-src)" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
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Below are the most recent publications written about "Proto-Oncogene Proteins pp60(c-src)" by people in Profiles.
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UV radiation resistance-associated gene (UVRAG) promotes cell proliferation, migration, invasion by regulating cyclin-dependent kinases (CDK) and integrin-?/Src signaling in breast cancer cells. Mol Cell Biochem. 2021 May; 476(5):2075-2084.
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Patient derived mutation W257G of PPP2R1A enhances cancer cell migration through SRC-JNK-c-Jun pathway. Sci Rep. 2016 06 07; 6:27391.
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NDN is an imprinted tumor suppressor gene that is downregulated in ovarian cancers through genetic and epigenetic mechanisms. Oncotarget. 2016 Jan 19; 7(3):3018-32.
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Unraveling the molecular architecture of a G protein-coupled receptor/?-arrestin/Erk module complex. Sci Rep. 2015 Jun 01; 5:10760.
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Src activity is modulated by oxaliplatin and correlates with outcomes after hepatectomy for metastatic colorectal cancer. BMC Cancer. 2014 Sep 10; 14:660.
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Self-reinforcing loop of amphiregulin and Y-box binding protein-1 contributes to poor outcomes in ovarian cancer. Oncogene. 2014 May 29; 33(22):2846-56.
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Sox4 is required for the survival of pro-B cells. J Immunol. 2013 Mar 01; 190(5):2080-9.
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Brk/PTK6 cooperates with HER2 and Src in regulating breast cancer cell survival and epithelial-to-mesenchymal transition. Cancer Biol Ther. 2013 Mar; 14(3):237-45.
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Mediators of receptor tyrosine kinase activation in infantile fibrosarcoma: a Children's Oncology Group study. J Pathol. 2012 Sep; 228(1):119-30.
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Modulating therapeutic effects of the c-Src inhibitor via oestrogen receptor and human epidermal growth factor receptor 2 in breast cancer cell lines. Eur J Cancer. 2012 Dec; 48(18):3488-98.