"Tumor Microenvironment" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The milieu surrounding neoplasms consisting of cells, vessels, soluble factors, and molecules, that can influence and be influenced by, the neoplasm's growth.
| Descriptor ID |
D059016
|
| MeSH Number(s) |
G04.366.500
|
| Concept/Terms |
Tumor Microenvironment- Tumor Microenvironment
- Microenvironment, Tumor
- Microenvironments, Tumor
- Tumor Microenvironments
Cancer Microenvironment- Cancer Microenvironment
- Cancer Microenvironments
- Microenvironment, Cancer
- Microenvironments, Cancer
|
Below are MeSH descriptors whose meaning is more general than "Tumor Microenvironment".
Below are MeSH descriptors whose meaning is more specific than "Tumor Microenvironment".
This graph shows the total number of publications written about "Tumor Microenvironment" by people in this website by year, and whether "Tumor Microenvironment" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 2 | 2 |
| 2011 | 2 | 3 | 5 |
| 2012 | 4 | 2 | 6 |
| 2013 | 0 | 5 | 5 |
| 2014 | 4 | 4 | 8 |
| 2015 | 2 | 10 | 12 |
| 2016 | 10 | 10 | 20 |
| 2017 | 6 | 18 | 24 |
| 2018 | 7 | 15 | 22 |
| 2019 | 14 | 19 | 33 |
| 2020 | 19 | 25 | 44 |
| 2021 | 11 | 28 | 39 |
| 2022 | 5 | 48 | 53 |
| 2023 | 5 | 46 | 51 |
| 2024 | 14 | 24 | 38 |
| 2025 | 11 | 22 | 33 |
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Below are the most recent publications written about "Tumor Microenvironment" by people in Profiles.
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TIGIT Affects CAR NK-cell Effector Function in the Solid Tumor Microenvironment by Modulating Immune Synapse Strength. Cancer Immunol Res. 2025 Oct 01; 13(10):1576-1590.
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Nrf2 Hyperactivation as a Driver of Radiotherapy Resistance and Suppressed Antitumor Immunity in Head and Neck Squamous Cell Carcinoma. Clin Cancer Res. 2025 Oct 01; 31(19):4184-4195.
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Divergent Roles of C/EBP? Isoforms LAP and LIP in Shaping T Cell Dysfunction and Tumor Progression in Triple-Negative Breast Cancer. FASEB J. 2025 Aug 31; 39(16):e70984.
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Characterization of the tumor immune microenvironment in pregnancy-associated breast cancer through multiplex immunohistochemistry and transcriptome analyses. Breast Cancer Res. 2025 Aug 26; 27(1):154.
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Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy. Nature. 2025 Oct; 646(8084):462-473.
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Constitutive IL-7 signaling promotes CAR-NK cell survival in the solid tumor microenvironment but impairs tumor control. J Immunother Cancer. 2025 Jul 23; 13(7).
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Integrative spatial omics reveals distinct tumor-promoting multicellular niches and immunosuppressive mechanisms in Black American and White American patients with TNBC. Nat Commun. 2025 Jul 17; 16(1):6584.
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Decoding metastatic microenvironments through single-cell omics reveals new insights into niche dynamics and tumor evolution. PLoS Biol. 2025 Jul; 23(7):e3003299.
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Src/FN1 pathway activation drives tumor cell cluster formation and metastasis in lung cancer: A promising therapeutic target. Sci Adv. 2025 Jul 11; 11(28):eadv7377.
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Ad-SGE-DKK3 Gene Therapy Overcomes Resistance to Immune Checkpoint Blockade in Pleural Mesothelioma. Clin Cancer Res. 2025 Jul 01; 31(13):2639-2654.