"Bcl-2-Like Protein 11" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A BCL-2-like protein that has a C-terminal BCL-2 homology (BH3) domain and forms heterodimers with other BCL-2 FAMILY PROTEINS. It is a strong inducer of APOPTOSIS and ANOIKIS; several isoforms are expressed (BimEL, Bim L, Bim-alpha, Bim-s; and Bim-gamma) that have different potencies for inducing apoptosis.
| Descriptor ID |
D000072224
|
| MeSH Number(s) |
D12.644.360.075.323 D12.776.476.075.323 D12.776.543.116 D12.776.624.664.700.025
|
| Concept/Terms |
Bcl-2-Like Protein 11- Bcl-2-Like Protein 11
- 11, Bcl-2-Like Protein
- Bcl 2 Like Protein 11
- Protein 11, Bcl-2-Like
- Bcl-2-Interacting Mediator of Cell Death
- Bcl 2 Interacting Mediator of Cell Death
- Bcl-2-Binding Protein, BIM
- BIM Bcl-2-Binding Protein
- Bcl 2 Binding Protein, BIM
- Protein, BIM Bcl-2-Binding
- BCL2L11 Protein
- Protein, BCL2L11
- BIM Protein
- Protein, BIM
|
Below are MeSH descriptors whose meaning is more general than "Bcl-2-Like Protein 11".
Below are MeSH descriptors whose meaning is more specific than "Bcl-2-Like Protein 11".
This graph shows the total number of publications written about "Bcl-2-Like Protein 11" by people in this website by year, and whether "Bcl-2-Like Protein 11" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 5 | 5 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 3 | 3 |
| 2011 | 0 | 5 | 5 |
| 2012 | 0 | 5 | 5 |
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 6 | 6 |
| 2015 | 0 | 6 | 6 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 2 | 3 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Bcl-2-Like Protein 11" by people in Profiles.
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Apoptosis Pathway-Associated Proteins Are Frequently Expressed in Melanoma: A Study of 32 Cases With Focus on Acral Lentiginous Melanoma. Am J Dermatopathol. 2024 Jul 01; 46(7):410-415.
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SNAI2-Mediated Repression of BIM Protects Rhabdomyosarcoma from Ionizing Radiation. Cancer Res. 2021 11 01; 81(21):5451-5463.
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Combined MEK and BCL-2/XL Inhibition Is Effective in High-Grade Serous Ovarian Cancer Patient-Derived Xenograft Models and BIM Levels Are Predictive of Responsiveness. Mol Cancer Ther. 2019 03; 18(3):642-655.
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Therapeutically targeting tumor microenvironment-mediated drug resistance in estrogen receptor-positive breast cancer. J Exp Med. 2018 03 05; 215(3):895-910.
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Flavopiridol enhances ABT-199 sensitivity in unfavourable-risk multiple myeloma cells in vitro and in vivo. Br J Cancer. 2018 02 06; 118(3):388-397.
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Bim suppresses the development of SLE by limiting myeloid inflammatory responses. J Exp Med. 2017 Dec 04; 214(12):3753-3773.
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The Imipridone ONC201 Induces Apoptosis and Overcomes Chemotherapy Resistance by Up-Regulation of Bim in Multiple Myeloma. Neoplasia. 2017 Oct; 19(10):772-780.
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JAK/STAT pathway inhibition overcomes IL7-induced glucocorticoid resistance in a subset of human T-cell acute lymphoblastic leukemias. Leukemia. 2017 12; 31(12):2568-2576.
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MLL-AF4 binds directly to a BCL-2 specific enhancer and modulates H3K27?acetylation. Exp Hematol. 2017 03; 47:64-75.
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Transcriptional repression by the HDAC4-RelB-p52 complex regulates multiple myeloma survival and growth. Nat Commun. 2015 Oct 12; 6:8428.