"Ankyrins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of membrane-associated proteins responsible for the attachment of the cytoskeleton. Erythrocyte-related isoforms of ankyrin attach the SPECTRIN cytoskeleton to a transmembrane protein (ANION EXCHANGE PROTEIN 1, ERYTHROCYTE) in the erythrocyte plasma membrane. Brain-related isoforms of ankyrin also exist.
| Descriptor ID |
D017487
|
| MeSH Number(s) |
D12.776.543.080
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ankyrins".
Below are MeSH descriptors whose meaning is more specific than "Ankyrins".
This graph shows the total number of publications written about "Ankyrins" by people in this website by year, and whether "Ankyrins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 1 | 0 | 1 |
| 2004 | 0 | 3 | 3 |
| 2006 | 2 | 1 | 3 |
| 2007 | 2 | 2 | 4 |
| 2008 | 3 | 3 | 6 |
| 2009 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 3 | 2 | 5 |
| 2013 | 0 | 2 | 2 |
| 2014 | 2 | 2 | 4 |
| 2015 | 1 | 2 | 3 |
| 2016 | 1 | 5 | 6 |
| 2018 | 1 | 1 | 2 |
| 2020 | 0 | 4 | 4 |
| 2021 | 4 | 0 | 4 |
| 2022 | 1 | 1 | 2 |
| 2023 | 0 | 1 | 1 |
| 2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "Ankyrins" by people in Profiles.
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Ankyrin-dependent Na+ channel clustering prevents neuromuscular synapse fatigue. Curr Biol. 2021 09 13; 31(17):3810-3819.e4.
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Wolff-Parkinson-White syndrome: De novo variants and evidence for mutational burden in genes associated with atrial fibrillation. Am J Med Genet A. 2020 06; 182(6):1387-1399.
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Ankyrin-G isoform imbalance and interneuronopathy link epilepsy and bipolar disorder. Mol Psychiatry. 2017 10; 22(10):1464-1472.
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CaMKII inhibition rescues proarrhythmic phenotypes in the model of human ankyrin-B syndrome. Heart Rhythm. 2012 Dec; 9(12):2034-41.
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Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation. Circulation. 2011 Sep 13; 124(11):1212-22.
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Molecular mimicry by an F-box effector of Legionella pneumophila hijacks a conserved polyubiquitination machinery within macrophages and protozoa. PLoS Pathog. 2009 Dec; 5(12):e1000704.
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A Dot/Icm-translocated ankyrin protein of Legionella pneumophila is required for intracellular proliferation within human macrophages and protozoa. Mol Microbiol. 2008 Nov; 70(4):908-23.
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Role for the Ankyrin eukaryotic-like genes of Legionella pneumophila in parasitism of protozoan hosts and human macrophages. Environ Microbiol. 2008 Jun; 10(6):1460-74.
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Identification of a critical ankyrin-binding loop on the cytoplasmic domain of erythrocyte membrane band 3 by crystal structure analysis and site-directed mutagenesis. J Biol Chem. 2003 Feb 28; 278(9):6879-84.
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Mutually exclusive distribution of the focal adhesion associated proteins and the erythrocyte membrane skeleton proteins in the human fibroblast plasma membrane undercoat. Cell Struct Funct. 1996 Feb; 21(1):27-39.