"Spectrin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A high molecular weight (220-250 kDa) water-soluble protein which can be extracted from erythrocyte ghosts in low ionic strength buffers. The protein contains no lipids or carbohydrates, is the predominant species of peripheral erythrocyte membrane proteins, and exists as a fibrous coating on the inner, cytoplasmic surface of the membrane.
| Descriptor ID |
D013049
|
| MeSH Number(s) |
D12.776.220.980 D12.776.543.850
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Spectrin".
Below are MeSH descriptors whose meaning is more specific than "Spectrin".
This graph shows the total number of publications written about "Spectrin" by people in this website by year, and whether "Spectrin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2004 | 2 | 0 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 3 | 1 | 4 |
| 2008 | 1 | 1 | 2 |
| 2009 | 2 | 0 | 2 |
| 2010 | 2 | 0 | 2 |
| 2011 | 1 | 2 | 3 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 2 | 3 |
| 2017 | 2 | 0 | 2 |
| 2018 | 4 | 0 | 4 |
| 2019 | 2 | 0 | 2 |
| 2020 | 2 | 1 | 3 |
| 2021 | 3 | 1 | 4 |
| 2022 | 1 | 1 | 2 |
| 2023 | 2 | 0 | 2 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Spectrin" by people in Profiles.
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Postsynaptic ?1?spectrin maintains Na+ channels at the neuromuscular junction. J Physiol. 2024 Mar; 602(6):1127-1145.
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?II-Spectrin Is Required for Synaptic Positioning during Retinal Development. J Neurosci. 2023 07 19; 43(29):5277-5289.
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Spectrin-beta 2 facilitates the selective accumulation of GABAA receptors at somatodendritic synapses. Commun Biol. 2023 01 05; 6(1):11.
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Pleiotropic Ankyrins: Scaffolds for Ion Channels and Transporters. Channels (Austin). 2022 12; 16(1):216-229.
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?IV-Spectrin Autoantibodies in 2 Individuals With Neuropathy of Possible Paraneoplastic Origin: A Case Series. Neurol Neuroimmunol Neuroinflamm. 2022 07; 9(4).
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Ankyrin-R Links Kv3.3 to the Spectrin Cytoskeleton and Is Required for Purkinje Neuron Survival. J Neurosci. 2022 01 05; 42(1):2-15.
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Spectrins. Curr Biol. 2021 05 24; 31(10):R504-R506.
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Heterozygous variants in SPTBN1 cause intellectual disability and autism. Am J Med Genet A. 2021 07; 185(7):2037-2045.
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Ankyrins and neurological disease. Curr Opin Neurobiol. 2021 08; 69:51-57.
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Mechanisms of node of Ranvier assembly. Nat Rev Neurosci. 2021 01; 22(1):7-20.