"Talin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 235-kDa cytoplasmic protein that is also found in platelets. It has been localized to regions of cell-substrate adhesion. It binds to INTEGRINS; VINCULIN; and ACTINS and appears to participate in generating a transmembrane connection between the extracellular matrix and the cytoskeleton.
| Descriptor ID |
D016608
|
| MeSH Number(s) |
D12.776.220.985
|
| Concept/Terms |
Talin- Talin
- Band 2 Protein
- Protein, Band 2
|
Below are MeSH descriptors whose meaning is more general than "Talin".
Below are MeSH descriptors whose meaning is more specific than "Talin".
This graph shows the total number of publications written about "Talin" by people in this website by year, and whether "Talin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Talin" by people in Profiles.
-
Critical role of integrin CD11c in splenic dendritic cell capture of missing-self CD47 cells to induce adaptive immunity. Proc Natl Acad Sci U S A. 2018 06 26; 115(26):6786-6791.
-
Wdr1-Dependent Actin Reorganization in Platelet Activation. PLoS One. 2016; 11(9):e0162897.
-
Cbl-associated protein regulates assembly and function of two tension-sensing structures in Drosophila. Development. 2013 Feb 01; 140(3):627-38.
-
Modulation of MicroRNA-194 and cell migration by HER2-targeting trastuzumab in breast cancer. PLoS One. 2012; 7(7):e41170.
-
Desmoplakin and talin2 are novel mRNA targets of fragile X-related protein-1 in cardiac muscle. Circ Res. 2011 Jul 22; 109(3):262-71.
-
Talin is required for integrin-mediated platelet function in hemostasis and thrombosis. J Exp Med. 2007 Dec 24; 204(13):3103-11.
-
Increased filamin binding to beta-integrin cytoplasmic domains inhibits cell migration. Nat Cell Biol. 2001 Dec; 3(12):1060-8.
-
Macromolecular composition of stress fiber-plasma membrane attachment sites in endothelial cells in situ. Circ Res. 1996 Nov; 79(5):1000-6.
-
Mutually exclusive distribution of the focal adhesion associated proteins and the erythrocyte membrane skeleton proteins in the human fibroblast plasma membrane undercoat. Cell Struct Funct. 1996 Feb; 21(1):27-39.
-
Focal adhesion proteins associated with apical stress fibers of human fibroblasts. Cell Motil Cytoskeleton. 1995; 31(3):177-95.