"Vinculin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytoskeletal protein associated with cell-cell and cell-matrix interactions. The amino acid sequence of human vinculin has been determined. The protein consists of 1066 amino acid residues and its gene has been assigned to chromosome 10.
| Descriptor ID |
D016596
|
| MeSH Number(s) |
D12.776.220.990
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Vinculin".
Below are MeSH descriptors whose meaning is more specific than "Vinculin".
This graph shows the total number of publications written about "Vinculin" by people in this website by year, and whether "Vinculin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 3 | 3 |
| 2000 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Vinculin" by people in Profiles.
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Relief of talin autoinhibition triggers a force-independent association with vinculin. J Cell Biol. 2020 01 06; 219(1).
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The Intracranial Aneurysm Gene THSD1 Connects Endosome Dynamics to Nascent Focal Adhesion Assembly. Cell Physiol Biochem. 2017; 43(6):2200-2211.
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Molecular Simulations Suggest a Force-Dependent Mechanism of Vinculin Activation. Biophys J. 2017 Oct 17; 113(8):1697-1710.
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VIncristine, irinotecan, and temozolomide in children and adolescents with relapsed rhabdomyosarcoma. Pediatr Blood Cancer. 2018 Jan; 65(1).
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The maternal-to-zygotic transition targets actin to promote robustness during morphogenesis. PLoS Genet. 2013 Nov; 9(11):e1003901.
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Cbl-associated protein regulates assembly and function of two tension-sensing structures in Drosophila. Development. 2013 Feb 01; 140(3):627-38.
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Vinculin regulates the recruitment and release of core focal adhesion proteins in a force-dependent manner. Curr Biol. 2013 Feb 18; 23(4):271-81.
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Renal cell carcinoma with novel VCL-ALK fusion: new representative of ALK-associated tumor spectrum. Mod Pathol. 2011 Mar; 24(3):430-42.
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Endothelial cell migration during murine yolk sac vascular remodeling occurs by means of a Rac1 and FAK activation pathway in vivo. Dev Dyn. 2010 Oct; 239(10):2570-83.
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Vinculin, an adapter protein in control of cell adhesion signalling. Eur J Cell Biol. 2011 Feb-Mar; 90(2-3):157-63.