"Cadherins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Calcium-dependent cell adhesion proteins. They are important in the formation of ADHERENS JUNCTIONS between cells. Cadherins are classified by their distinct immunological and tissue specificities, either by letters (E- for epithelial, N- for neural, and P- for placental cadherins) or by numbers (cadherin-12 or N-cadherin 2 for brain-cadherin). Cadherins promote cell adhesion via a homophilic mechanism as in the construction of tissues and of the whole animal body.
| Descriptor ID |
D015820
|
| MeSH Number(s) |
D12.776.395.550.200.200 D12.776.543.550.200.200 D23.050.301.350.200
|
| Concept/Terms |
P-Cadherins- P-Cadherins
- P Cadherins
- P-Cadherin
- P Cadherin
- Placental Cadherins
- Cadherins, Placental
- Cadherin-3
- Cadherin 3
E-Cadherins- E-Cadherins
- E Cadherins
- Uvomorulin
- Epithelial-Cadherins
- Epithelial Cadherins
- Cadherin-1
- Cadherin 1
- E-Cadherin
- E Cadherin
N-Cadherins- N-Cadherins
- N Cadherins
- N-Cadherin
- N Cadherin
- Neural Cadherins
- Cadherins, Neural
- Cadherin-2
- Cadherin 2
|
Below are MeSH descriptors whose meaning is more general than "Cadherins".
Below are MeSH descriptors whose meaning is more specific than "Cadherins".
This graph shows the total number of publications written about "Cadherins" by people in this website by year, and whether "Cadherins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 3 | 3 | 6 |
| 2002 | 2 | 3 | 5 |
| 2003 | 3 | 4 | 7 |
| 2004 | 0 | 3 | 3 |
| 2005 | 2 | 5 | 7 |
| 2006 | 3 | 4 | 7 |
| 2007 | 1 | 4 | 5 |
| 2008 | 1 | 4 | 5 |
| 2009 | 0 | 5 | 5 |
| 2010 | 2 | 2 | 4 |
| 2011 | 3 | 4 | 7 |
| 2012 | 6 | 1 | 7 |
| 2013 | 2 | 1 | 3 |
| 2014 | 3 | 4 | 7 |
| 2015 | 1 | 7 | 8 |
| 2016 | 2 | 4 | 6 |
| 2017 | 2 | 6 | 8 |
| 2018 | 2 | 7 | 9 |
| 2019 | 5 | 3 | 8 |
| 2020 | 1 | 3 | 4 |
| 2022 | 2 | 1 | 3 |
| 2023 | 0 | 3 | 3 |
| 2024 | 2 | 1 | 3 |
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click here.
Below are the most recent publications written about "Cadherins" by people in Profiles.
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MTOR maintains endothelial cell integrity to limit lung vascular injury. J Biol Chem. 2024 Dec; 300(12):107952.
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De novo heterozygous missense variants in CELSR1 as cause of fetal pleural effusions and progressive fetal hydrops. J Med Genet. 2024 May 21; 61(6):549-552.
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Cadherin-11 targeted cell-specific liposomes enabled skin fibrosis treatment by inducing apoptosis. J Control Release. 2024 Jun; 370:110-123.
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CADHERIN-11 regulation of myeloid phagocytes and autoimmune inflammation in murine lupus. J Autoimmun. 2024 05; 145:103197.
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E-cadherin loss drives diffuse-type gastric tumorigenesis via EZH2-mediated reprogramming. J Exp Med. 2024 Apr 01; 221(4).
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Stabilization of E-cadherin adhesions by COX-2/GSK3? signaling is a targetable pathway in metastatic breast cancer. JCI Insight. 2023 03 22; 8(6).
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Cell cycle-dependent palmitoylation of protocadherin 7 by ZDHHC5 promotes successful cytokinesis. J Cell Sci. 2023 03 15; 136(6).
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In colon cancer cells fascin1 regulates adherens junction remodeling. FASEB J. 2023 03; 37(3):e22786.
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The diagnostic significance of CDH17-positive circulating tumor cells in patients with colorectal cancer. Expert Rev Mol Diagn. 2023 02; 23(2):171-179.
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Bone Metastasis Initiation Is Coupled with Bone Remodeling through Osteogenic Differentiation of NG2+ Cells. Cancer Discov. 2023 02 06; 13(2):474-495.