"CD146 Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cell adhesion molecule of the immunoglobulin superfamily that is expressed by ENDOTHELIAL CELLS where it functions to stabilize INTERCELLULAR JUNCTIONS. It is also highly expressed by melanoma tumor cells and may facilitate their METASTASIS.
| Descriptor ID |
D051929
|
| MeSH Number(s) |
D12.776.395.550.200.170 D12.776.543.550.200.140 D12.776.624.301.249 D23.050.285.439.249 D23.050.301.350.150
|
| Concept/Terms |
CD146 Antigen- CD146 Antigen
- Antigen, CD146
- S-Endo 1 Endothelial-Associated Antigen
- Melanoma Cell Adhesion Molecule
- CD146 Antigens
- Antigens, CD146
- Gicerin
- Glycoprotein MUC18
- MUC18, Glycoprotein
|
Below are MeSH descriptors whose meaning is more general than "CD146 Antigen".
Below are MeSH descriptors whose meaning is more specific than "CD146 Antigen".
This graph shows the total number of publications written about "CD146 Antigen" by people in this website by year, and whether "CD146 Antigen" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 4 | 4 |
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 4 | 4 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 1 | 2 |
| 2013 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2020 | 0 | 2 | 2 |
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Below are the most recent publications written about "CD146 Antigen" by people in Profiles.
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Characterization of novel neutralizing mouse monoclonal antibody JM1-24-3 developed against MUC18 in metastatic melanoma. J Exp Clin Cancer Res. 2020 Dec 05; 39(1):273.
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Integrative Genomic Analysis Reveals Four Protein Biomarkers for Platelet Traits. Circ Res. 2020 10 09; 127(9):1182-1194.
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MCAM Mediates Chemoresistance in Small-Cell Lung Cancer via the PI3K/AKT/SOX2 Signaling Pathway. Cancer Res. 2017 08 15; 77(16):4414-4425.
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Cell-surface expression of neuron-glial antigen 2 (NG2) and melanoma cell adhesion molecule (CD146) in heterogeneous cultures of marrow-derived mesenchymal stem cells. Tissue Eng Part A. 2013 Oct; 19(19-20):2253-66.
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Expression of Id-1 is regulated by MCAM/MUC18: a missing link in melanoma progression. Cancer Res. 2011 May 15; 71(10):3494-504.
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Transforming growth factor-beta increases the expression of vascular smooth muscle cell markers in human multi-lineage progenitor cells. Med Sci Monit. 2011 Feb 25; 17(3):BR55-61.
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CREB inhibits AP-2alpha expression to regulate the malignant phenotype of melanoma. PLoS One. 2010 Aug 27; 5(8):e12452.
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Crosstalk between protease-activated receptor 1 and platelet-activating factor receptor regulates melanoma cell adhesion molecule (MCAM/MUC18) expression and melanoma metastasis. J Biol Chem. 2009 Oct 16; 284(42):28845-55.
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Active Notch1 confers a transformed phenotype to primary human melanocytes. Cancer Res. 2009 Jul 01; 69(13):5312-20.
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A subset of host B lymphocytes controls melanoma metastasis through a melanoma cell adhesion molecule/MUC18-dependent interaction: evidence from mice and humans. Cancer Res. 2008 Oct 15; 68(20):8419-28.