"Nectins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of calcium-independent cell adhesion molecules of the immunoglobulin superfamily. They are expressed by most cell types and mediate both homotypic and heterotypic cell-cell adhesion. Nectins function in a variety of morphogenetic and developmental processes that include organogenesis of the eye, ear, tooth, and cerebral cortex; they also play roles in viral infection and cell proliferation.
| Descriptor ID |
D000075983
|
| MeSH Number(s) |
D12.776.395.550.200.123 D12.776.543.550.200.130 D23.050.301.350.123
|
| Concept/Terms |
Nectin-2- Nectin-2
- Nectin 2
- CD112 Antigen
- Antigen, CD112
Nectin-3- Nectin-3
- Nectin 3
- CD113 Antigen
- Antigen, CD113
Nectin-1- Nectin-1
- Nectin 1
- Herpesvirus Entry Mediator C
- Human Poliovirus Receptor Related 1
- PVRL1
- CD111 Antigen
- Antigen, CD111
- HevC Protein
- Poliovirus Receptor-Related Protein 1
- Poliovirus Receptor Related Protein 1
- Prr1 Protein
|
Below are MeSH descriptors whose meaning is more general than "Nectins".
Below are MeSH descriptors whose meaning is more specific than "Nectins".
This graph shows the total number of publications written about "Nectins" by people in this website by year, and whether "Nectins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Nectins" by people in Profiles.
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Nectin-4 Positivity in Genitourinary Malignancies: A Systematic Review. JCO Precis Oncol. 2024 Dec; 8:e2400470.
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Nectin-4 expression in a subset of cutaneous adnexal carcinomas: A potential target for therapy with enfortumab vedotin. J Cutan Pathol. 2024 May; 51(5):360-367.
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A role for PVRL4-driven cell-cell interactions in tumorigenesis. Elife. 2013 Apr 30; 2:e00358.
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Nectin-2 and N-cadherin interact through extracellular domains and induce apical accumulation of F-actin in apical constriction of Xenopus neural tube morphogenesis. Development. 2010 Apr; 137(8):1315-25.
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Crystallization and preliminary X-ray analysis of the V domain of human nectin-2. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Jun 01; 65(Pt 6):615-7.