Epithelial Cell Adhesion Molecule
"Epithelial Cell Adhesion Molecule" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cell adhesion molecule that is expressed on the membranes of nearly all EPITHELIAL CELLS, especially at the junctions between intestinal epithelial cells and intraepithelial LYMPHOCYTES. It also is expressed on the surface of ADENOCARCINOMA and epithelial tumor cells. It may function in the MUCOSA through homophilic interactions to provide a barrier against infection. It also regulates the proliferation and differentiation of EMBRYONIC STEM CELLS.
| Descriptor ID |
D000071858
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| MeSH Number(s) |
D12.776.395.550.200.263 D12.776.543.550.200.263 D23.050.285.357 D23.050.301.350.263
|
| Concept/Terms |
Epithelial Cell Adhesion Molecule- Epithelial Cell Adhesion Molecule
- CD326 Protein
- Antigen, CD326
- CD326 Antigen
- ESA Antigen
- Antigen, ESA
- EpCAM
- GA733 Antigen
- Antigen, GA733
- GA733 Tumor-Associated Antigen
- GA733 Tumor Associated Antigen
- Tumor-Associated Antigen, GA733
- Tacstd1 Protein
- Epithelial Specific Antigen
- Antigen, Epithelial Specific
- Ep-CAM
- Tumor-Associated Antigen GA733
- GA733, Tumor-Associated Antigen
- Tumor Associated Antigen GA733
- GA 733 Tumor-Associated Antigen
- GA 733 Tumor Associated Antigen
|
Below are MeSH descriptors whose meaning is more general than "Epithelial Cell Adhesion Molecule".
Below are MeSH descriptors whose meaning is more specific than "Epithelial Cell Adhesion Molecule".
This graph shows the total number of publications written about "Epithelial Cell Adhesion Molecule" by people in this website by year, and whether "Epithelial Cell Adhesion Molecule" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Epithelial Cell Adhesion Molecule" by people in Profiles.
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EpCAM-targeted betulinic acid analogue nanotherapy improves therapeutic efficacy and induces anti-tumorigenic immune response in colorectal cancer tumor microenvironment. J Biomed Sci. 2024 Aug 20; 31(1):81.
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Mesothelial cells with mesenchymal features enhance peritoneal dissemination by forming a protumorigenic microenvironment. Cell Rep. 2024 01 23; 43(1):113613.
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High-yield enrichment of mouse small intestine intraepithelial lymphocytes by immunomagnetic depletion of EpCAM+ cells. STAR Protoc. 2022 03 18; 3(1):101207.
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EpCAM-independent isolation of circulating tumor cells with epithelial-to-mesenchymal transition and cancer stem cell phenotypes using ApoStream? in patients with breast cancer treated with primary systemic therapy. PLoS One. 2020; 15(3):e0229903.
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Joint single-cell DNA accessibility and protein epitope profiling reveals environmental regulation of epigenomic heterogeneity. Nat Commun. 2018 11 02; 9(1):4590.
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Molecular characterization of breast cancer CTCs associated with brain metastasis. Nat Commun. 2017 08 04; 8(1):196.
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Human spermatogonial stem cells display limited proliferation in?vitro under mouse spermatogonial stem cell culture conditions. Fertil Steril. 2016 Nov; 106(6):1539-1549.e8.
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The isolation and characterization of CTC subsets related to breast cancer dormancy. Sci Rep. 2015 Dec 03; 5:17533.
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Detection and enumeration of circulating tumor cells based on their invasive property. Oncotarget. 2015 Sep 29; 6(29):27304-11.
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TP53 loss creates therapeutic vulnerability in?colorectal cancer. Nature. 2015 Apr 30; 520(7549):697-701.