Epithelial Cell Adhesion Molecule
"Epithelial Cell Adhesion Molecule" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cell adhesion molecule that is expressed on the membranes of nearly all EPITHELIAL CELLS, especially at the junctions between intestinal epithelial cells and intraepithelial LYMPHOCYTES. It also is expressed on the surface of ADENOCARCINOMA and epithelial tumor cells. It may function in the MUCOSA through homophilic interactions to provide a barrier against infection. It also regulates the proliferation and differentiation of EMBRYONIC STEM CELLS.
| Descriptor ID |
D000071858
|
| MeSH Number(s) |
D12.776.395.550.200.263 D12.776.543.550.200.263 D23.050.285.357 D23.050.301.350.263
|
| Concept/Terms |
Epithelial Cell Adhesion Molecule- Epithelial Cell Adhesion Molecule
- CD326 Protein
- Antigen, CD326
- CD326 Antigen
- ESA Antigen
- Antigen, ESA
- EpCAM
- GA733 Antigen
- Antigen, GA733
- GA733 Tumor-Associated Antigen
- GA733 Tumor Associated Antigen
- Tumor-Associated Antigen, GA733
- Tacstd1 Protein
- Epithelial Specific Antigen
- Antigen, Epithelial Specific
- Ep-CAM
- Tumor-Associated Antigen GA733
- GA733, Tumor-Associated Antigen
- Tumor Associated Antigen GA733
- GA 733 Tumor-Associated Antigen
- GA 733 Tumor Associated Antigen
|
Below are MeSH descriptors whose meaning is more general than "Epithelial Cell Adhesion Molecule".
Below are MeSH descriptors whose meaning is more specific than "Epithelial Cell Adhesion Molecule".
This graph shows the total number of publications written about "Epithelial Cell Adhesion Molecule" by people in this website by year, and whether "Epithelial Cell Adhesion Molecule" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Epithelial Cell Adhesion Molecule" by people in Profiles.
-
EpCAM-targeted betulinic acid analogue nanotherapy improves therapeutic efficacy and induces anti-tumorigenic immune response in colorectal cancer tumor microenvironment. J Biomed Sci. 2024 Aug 20; 31(1):81.
-
EpCam is required for maintaining the integrity of the biliary epithelium. Liver Int. 2021 09; 41(9):2132-2138.
-
IL15 Trispecific Killer Engagers (TriKE) Make Natural Killer Cells Specific to CD33+ Targets While Also Inducing Persistence, In Vivo Expansion, and Enhanced Function. Clin Cancer Res. 2016 07 15; 22(14):3440-50.
-
TP53 loss creates therapeutic vulnerability in?colorectal cancer. Nature. 2015 Apr 30; 520(7549):697-701.
-
Epithelial-mesenchymal transition and stem cell markers in patients with HER2-positive metastatic breast cancer. Mol Cancer Ther. 2012 Nov; 11(11):2526-34.
-
Further evidence for EpCAM as the gene for congenital tufting enteropathy. Am J Med Genet A. 2010 Jan; 152A(1):222-4.
-
Identification of EpCAM as a molecular target of prostate cancer stroma. Am J Pathol. 2009 Dec; 175(6):2277-87.
-
Inflammatory cytokine tumor necrosis factor alpha confers precancerous phenotype in an organoid model of normal human ovarian surface epithelial cells. Neoplasia. 2009 Jun; 11(6):529-41.
-
Identification of epithelial cell adhesion molecule autoantibody in patients with ovarian cancer. Clin Cancer Res. 2003 Oct 15; 9(13):4782-91.