"Basigin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A widely distributed cell surface transmembrane glycoprotein characterized by extracellular IMMUNOGLOBULIN DOMAINS. It stimulates the synthesis of MATRIX METALLOPROTEINASES and is found at high levels on the surface of malignant NEOPLASMS where it may play a role as a mediator of malignant cell behavior.
| Descriptor ID |
D051926
|
| MeSH Number(s) |
D12.776.395.550.045 D12.776.543.550.187 D23.050.285.040
|
| Concept/Terms |
Basigin- Basigin
- Emmprin
- CD147 Antigens
- Extracellular Matrix Metalloproteinase Inducer (EMMPRIN)
- Emmprin Protein
- Basigin Protein
- CD147 Antigen
- Antigen, CD147
- Antigens, CD147
|
Below are MeSH descriptors whose meaning is more general than "Basigin".
Below are MeSH descriptors whose meaning is more specific than "Basigin".
This graph shows the total number of publications written about "Basigin" by people in this website by year, and whether "Basigin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2006 | 2 | 0 | 2 |
| 2020 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Basigin" by people in Profiles.
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QM107, a novel CD148 (RTP Type J) activating peptide therapy for treating neovascular age-related macular degeneration. Br J Pharmacol. 2025 Feb; 182(4):951-968.
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Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma. Nat Commun. 2020 09 23; 11(1):4810.
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Expression of MMP9 and CD147 in invasive squamous cell carcinoma of the uterine cervix and their implication. Pathol Res Pract. 2009; 205(10):709-15.
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A phase 2/3 multicenter randomized clinical trial of ABX-CBL versus ATG as secondary therapy for steroid-resistant acute graft-versus-host disease. Blood. 2007 Mar 15; 109(6):2657-62.
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Cyclophilin A is overexpressed in human pancreatic cancer cells and stimulates cell proliferation through CD147. Cancer. 2006 May 15; 106(10):2284-94.
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Effect of cyclophilin A on gene expression in human pancreatic cancer cells. Am J Surg. 2005 Nov; 190(5):739-45.
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Roles of cyclophilins in cancers and other organ systems. World J Surg. 2005 Mar; 29(3):276-80.
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Treatment of steroid-refractory acute graft-versus-host disease with anti-CD147 monoclonal antibody ABX-CBL. Blood. 2001 Oct 01; 98(7):2052-8.
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Measurement of matrix metalloproteinases and tissue inhibitors of metalloproteinases in blood and tissues. Clinical and experimental applications. Ann N Y Acad Sci. 1999 Jun 30; 878:212-27.