"GAP-43 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nervous tissue specific protein which is highly expressed in NEURONS during development and NERVE REGENERATION. It has been implicated in neurite outgrowth, long-term potentiation, SIGNAL TRANSDUCTION, and NEUROTRANSMITTER release. (From Neurotoxicology 1994;15(1):41-7) It is also a substrate of PROTEIN KINASE C.
| Descriptor ID |
D019922
|
| MeSH Number(s) |
D12.776.395.550.400 D12.776.543.550.400 D12.776.631.400
|
| Concept/Terms |
GAP-43 Protein- GAP-43 Protein
- GAP 43 Protein
- Phosphoprotein B-50
- Phosphoprotein B 50
- GAP-43
- Neuromodulin
- Growth-Associated Protein 43
- Growth Associated Protein 43
- Phosphoprotein pp46
- B-50 Protein
- B 50 Protein
- GAP43 Protein
- Nerve Growth Cone Membrane Protein GAP-43
- Nerve Growth Cone Membrane Protein GAP 43
- Phosphoprotein F1
|
Below are MeSH descriptors whose meaning is more general than "GAP-43 Protein".
Below are MeSH descriptors whose meaning is more specific than "GAP-43 Protein".
This graph shows the total number of publications written about "GAP-43 Protein" by people in this website by year, and whether "GAP-43 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 1 | 2 |
| 2002 | 0 | 1 | 1 |
| 2005 | 1 | 2 | 3 |
| 2007 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "GAP-43 Protein" by people in Profiles.
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Smad4-dependent morphogenic signals control the maturation and axonal targeting of basal vomeronasal sensory neurons to the accessory olfactory bulb. Development. 2020 04 27; 147(8).
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Neuronal degeneration and regeneration induced by axotomy in the olfactory epithelium of Xenopus laevis. Dev Neurobiol. 2017 11; 77(11):1308-1320.
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Dorsal Root Ganglion Infiltration by Macrophages Contributes to?Paclitaxel Chemotherapy-Induced Peripheral Neuropathy. J Pain. 2016 07; 17(7):775-86.
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Axonal regeneration in the organotypically cultured monkey retina: biological aspects, dependence on substrates and age-related proteomic profiling. Restor Neurol Neurosci. 2008; 26(4-5):249-66.
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Brain tissue microarrays in neurodegenerative diseases: validation of methodology and immunohistochemical study of growth-associated protein-43 and calretinin. Pathol Int. 2007 Dec; 57(12):775-83.
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An investigation into the potential for activity-dependent regeneration of the rubrospinal tract after spinal cord injury. Eur J Neurosci. 2005 Dec; 22(12):3025-35.
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Detection of genes for ordinal traits in nuclear families and a unified approach for association studies. Genetics. 2006 Jan; 172(1):693-9.
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Cellular distribution of interleukin-1alpha-immunoreactivity after MPTP intoxication in mice. Brain Res Mol Brain Res. 2005 Aug 18; 138(2):156-63.
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Presynaptic protein kinase C controls maturation and branch dynamics of developing retinotectal arbors: possible role in activity-driven sharpening. J Neurobiol. 2004 Feb 15; 58(3):328-40.
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Atypical cells in human cutaneous re-excision scars for melanoma express p75NGFR, C56/N-CAM and GAP-43: evidence of early Schwann cell differentiation. J Cutan Pathol. 2002 Aug; 29(7):397-406.