"Tubulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A microtubule subunit protein found in large quantities in mammalian brain. It has also been isolated from SPERM FLAGELLUM; CILIA; and other sources. Structurally, the protein is a dimer with a molecular weight of approximately 120,000 and a sedimentation coefficient of 5.8S. It binds to COLCHICINE; VINCRISTINE; and VINBLASTINE.
| Descriptor ID |
D014404
|
| MeSH Number(s) |
D05.750.078.734.800 D12.776.220.600.800 D12.776.631.920
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Tubulin".
Below are MeSH descriptors whose meaning is more specific than "Tubulin".
This graph shows the total number of publications written about "Tubulin" by people in this website by year, and whether "Tubulin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 2 | 3 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2012 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 3 | 4 |
| 2016 | 1 | 2 | 3 |
| 2017 | 1 | 0 | 1 |
| 2019 | 0 | 2 | 2 |
| 2020 | 1 | 1 | 2 |
| 2021 | 2 | 0 | 2 |
| 2022 | 1 | 1 | 2 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tubulin" by people in Profiles.
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Mutations in the ?-tubulin TUBB impair ciliogenesis and are associated with ciliopathy-like phenotypes. Nat Commun. 2025 Nov 27; 16(1):10637.
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Bi-allelic CAMSAP1 variants cause a clinically recognizable neuronal migration disorder. Am J Hum Genet. 2022 11 03; 109(11):2068-2079.
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Cryo-ET of Toxoplasma parasites gives subnanometer insight into tubulin-based structures. Proc Natl Acad Sci U S A. 2022 02 08; 119(6).
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Exome sequencing of child-parent trios with bladder exstrophy: Findings in 26 children. Am J Med Genet A. 2021 10; 185(10):3028-3041.
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Molecular determinants for a-tubulin methylation by SETD2. J Biol Chem. 2021 07; 297(1):100898.
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TUBB4A mutations result in both glial and neuronal degeneration in an H-ABC leukodystrophy mouse model. Elife. 2020 05 28; 9.
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Bioreductively Activatable Prodrug Conjugates of Combretastatin A-1 and Combretastatin A-4 as Anticancer Agents Targeted toward Tumor-Associated Hypoxia. J Nat Prod. 2020 04 24; 83(4):937-954.
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Bi-allelic Pathogenic Variants in TUBGCP2 Cause Microcephaly and Lissencephaly Spectrum Disorders. Am J Hum Genet. 2019 11 07; 105(5):1005-1015.
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Characterization of neuromas in peripheral nerves and their effects on heterotopic bone formation. Mol Pain. 2019 Jan-Dec; 15:1744806919838191.
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An exome sequencing study of Moebius syndrome including atypical cases reveals an individual with CFEOM3A and a TUBB3 mutation. Cold Spring Harb Mol Case Stud. 2017 03; 3(2):a000984.