"Protein Aggregates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Any mixture of secondary, tertiary, or quaternary protein molecules which appear as clumps in or outside the cell.
| Descriptor ID |
D066329
|
| MeSH Number(s) |
D05.875
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protein Aggregates".
Below are MeSH descriptors whose meaning is more specific than "Protein Aggregates".
This graph shows the total number of publications written about "Protein Aggregates" by people in this website by year, and whether "Protein Aggregates" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 2 | 1 | 3 |
| 2018 | 1 | 2 | 3 |
| 2019 | 1 | 1 | 2 |
| 2020 | 0 | 2 | 2 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 2 | 2 |
| 2023 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
| 2025 | 1 | 1 | 2 |
| 2026 | 2 | 1 | 3 |
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Below are the most recent publications written about "Protein Aggregates" by people in Profiles.
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Condensate State as Determinant of Amyloid Pathology in Neurodegeneration. Biomolecules. 2026 Apr 10; 16(4).
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Modulation of Biomolecular Aggregate Morphology and Condensate Infectivity. Biomolecules. 2026 Mar 25; 16(4).
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Modulation of a-Synuclein Oligomer and Aggregate Populations by pH and Metal Ions. Biomolecules. 2026 02 20; 16(2).
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Repeat-associated non-AUG translation as a common mechanism for the polyGln ataxias. Cell Rep. 2026 Jan 27; 45(1):116741.
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Development of carbazole-based molecules for inhibition of mutant hSOD1 protein aggregation in Amyotrophic Lateral Sclerosis. Bioorg Med Chem. 2025 Apr 01; 120:118091.
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Evaluation of Alpha-Synuclein and Tau Antiaggregation Activity of Urea and Thiourea-Based Small Molecules for Neurodegenerative Disease Therapeutics. ACS Chem Neurosci. 2024 11 06; 15(21):3915-3931.
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Fluorescence Lifetime Imaging Microscopy of Biomolecular Condensates. Methods Mol Biol. 2023; 2563:135-148.
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Integrated multi-omics analysis of Huntington disease identifies pathways that modulate protein aggregation. Dis Model Mech. 2022 10 01; 15(10).
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Bmi1 suppresses protein synthesis and promotes proteostasis in hematopoietic stem cells. Genes Dev. 2022 08 01; 36(15-16):887-900.
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1-Indanone and 1,3-indandione Derivatives as Ligands for Misfolded a-Synuclein Aggregates. ChemMedChem. 2022 01 19; 17(2):e202100611.