"Protein Aggregates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Any mixture of secondary, tertiary, or quaternary protein molecules which appear as clumps in or outside the cell.
| Descriptor ID |
D066329
|
| MeSH Number(s) |
D05.875
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protein Aggregates".
Below are MeSH descriptors whose meaning is more specific than "Protein Aggregates".
This graph shows the total number of publications written about "Protein Aggregates" by people in this website by year, and whether "Protein Aggregates" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 2 | 2 |
| 2017 | 2 | 1 | 3 |
| 2018 | 1 | 3 | 4 |
| 2019 | 1 | 1 | 2 |
| 2020 | 0 | 3 | 3 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Protein Aggregates" by people in Profiles.
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Fluorescence Lifetime Imaging Microscopy of Biomolecular Condensates. Methods Mol Biol. 2023; 2563:135-148.
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Bmi1 suppresses protein synthesis and promotes proteostasis in hematopoietic stem cells. Genes Dev. 2022 08 01; 36(15-16):887-900.
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1-Indanone and 1,3-indandione Derivatives as Ligands for Misfolded a-Synuclein Aggregates. ChemMedChem. 2022 01 19; 17(2):e202100611.
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Electrostatic modulation of hnRNPA1 low-complexity domain liquid-liquid phase separation and aggregation. Protein Sci. 2021 07; 30(7):1408-1417.
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Pooled CRISPR screens with imaging on microraft arrays reveals stress granule-regulatory factors. Nat Methods. 2020 Jun; 17(6):636-642.
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Acute zoster plasma contains elevated amyloid, correlating with A?42 and amylin levels, and is amyloidogenic. J Neurovirol. 2020 06; 26(3):422-428.
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A plant pentatricopeptide repeat protein with a DYW-deaminase domain is sufficient for catalyzing C-to-U RNA editing in vitro. J Biol Chem. 2020 03 13; 295(11):3497-3505.
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OCIAD1 contributes to neurodegeneration in Alzheimer's disease by inducing mitochondria dysfunction, neuronal vulnerability and synaptic damages. EBioMedicine. 2020 Jan; 51:102569.
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Targeting a-Synuclein in Parkinson's Disease: Progress Towards the Development of Disease-Modifying Therapeutics. Drugs. 2019 Jun; 79(8):797-810.
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Single-molecule fluorescence studies of intrinsically disordered proteins and liquid phase separation. Biochim Biophys Acta Proteins Proteom. 2019 10; 1867(10):980-987.