"tau Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (NEUROFIBRILLARY TANGLES; NEUROPIL THREADS) in numerous neurodegenerative disorders (ALZHEIMER DISEASE; TAUOPATHIES).
| Descriptor ID |
D016875
|
| MeSH Number(s) |
D12.776.220.600.450.510 D12.776.631.560.510
|
| Concept/Terms |
tau Proteins- tau Proteins
- Proteins, tau
- tau Protein
- Protein, tau
|
Below are MeSH descriptors whose meaning is more general than "tau Proteins".
Below are MeSH descriptors whose meaning is more specific than "tau Proteins".
This graph shows the total number of publications written about "tau Proteins" by people in this website by year, and whether "tau Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 3 | 2 | 5 |
| 2002 | 1 | 1 | 2 |
| 2003 | 2 | 1 | 3 |
| 2004 | 0 | 1 | 1 |
| 2005 | 3 | 1 | 4 |
| 2006 | 3 | 3 | 6 |
| 2007 | 2 | 0 | 2 |
| 2008 | 2 | 3 | 5 |
| 2009 | 1 | 0 | 1 |
| 2010 | 4 | 2 | 6 |
| 2011 | 5 | 2 | 7 |
| 2012 | 3 | 1 | 4 |
| 2013 | 7 | 1 | 8 |
| 2014 | 8 | 1 | 9 |
| 2015 | 3 | 1 | 4 |
| 2016 | 7 | 2 | 9 |
| 2017 | 2 | 1 | 3 |
| 2018 | 10 | 1 | 11 |
| 2019 | 5 | 3 | 8 |
| 2020 | 4 | 4 | 8 |
| 2021 | 4 | 1 | 5 |
| 2022 | 0 | 7 | 7 |
| 2023 | 2 | 5 | 7 |
| 2024 | 7 | 4 | 11 |
| 2025 | 13 | 6 | 19 |
| 2026 | 4 | 2 | 6 |
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Below are the most recent publications written about "tau Proteins" by people in Profiles.
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Plasma Biomarkers of Brain Injury in Critically Ill Children Receiving Extracorporeal Membrane Oxygenation. JAMA Pediatr. 2026 Jun 01; 180(6):639-649.
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2-aminobutyrate mediates the impact of air pollution on blood biomarkers of Alzheimer's disease. Alzheimers Dement. 2026 05; 22(5):e71388.
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Condensate State as Determinant of Amyloid Pathology in Neurodegeneration. Biomolecules. 2026 Apr 10; 16(4).
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Tubulin transforms Tau and a-synuclein condensates from pathological to physiological. Nat Commun. 2026 Mar 03; 17(1).
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Systems genetic dissection of brain gene expression reveals excitotoxic mechanisms of Alzheimer's disease. Mol Psychiatry. 2026 Jun; 31(6):3462-3481.
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The NIH toolbox emotion battery and cerebrospinal fluid biomarkers in Alzheimer's disease: findings from the multisite ARMADA study. J Gerontol B Psychol Sci Soc Sci. 2026 01 12; 81(2).
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Concurrent detection of cognitive impairment and amyloid positivity with a multimodal machine learning-enabled digital cognitive assessment. Alzheimers Res Ther. 2025 12 11; 17(1):261.
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Higher Amyloid and Tau Burden Is Associated With Faster Decline on a Digital Cognitive Test. Ann Clin Transl Neurol. 2026 Mar; 13(3):562-573.
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Cognitive reserve predicts baseline tau burden in the U.S. POINTER trial imaging cohort. Alzheimers Dement. 2025 11; 21(11):e70892.
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Phosphorylation at serine 214 correlates with tau seeding activity in an age-dependent manner in two mouse models for tauopathies and is required for tau transsynaptic propagation. J Alzheimers Dis. 2025 Oct; 107(4):1706-1720.