"tau Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (NEUROFIBRILLARY TANGLES; NEUROPIL THREADS) in numerous neurodegenerative disorders (ALZHEIMER DISEASE; TAUOPATHIES).
| Descriptor ID |
D016875
|
| MeSH Number(s) |
D12.776.220.600.450.510 D12.776.631.560.510
|
| Concept/Terms |
tau Proteins- tau Proteins
- Proteins, tau
- tau Protein
- Protein, tau
|
Below are MeSH descriptors whose meaning is more general than "tau Proteins".
Below are MeSH descriptors whose meaning is more specific than "tau Proteins".
This graph shows the total number of publications written about "tau Proteins" by people in this website by year, and whether "tau Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2001 | 3 | 2 | 5 |
| 2002 | 1 | 1 | 2 |
| 2003 | 2 | 1 | 3 |
| 2004 | 0 | 1 | 1 |
| 2005 | 3 | 1 | 4 |
| 2006 | 3 | 3 | 6 |
| 2007 | 2 | 1 | 3 |
| 2008 | 2 | 3 | 5 |
| 2009 | 2 | 0 | 2 |
| 2010 | 4 | 1 | 5 |
| 2011 | 5 | 2 | 7 |
| 2012 | 3 | 2 | 5 |
| 2013 | 7 | 1 | 8 |
| 2014 | 8 | 3 | 11 |
| 2015 | 2 | 2 | 4 |
| 2016 | 6 | 2 | 8 |
| 2017 | 2 | 1 | 3 |
| 2018 | 10 | 1 | 11 |
| 2019 | 3 | 2 | 5 |
| 2020 | 3 | 1 | 4 |
| 2021 | 3 | 1 | 4 |
| 2022 | 0 | 4 | 4 |
| 2023 | 3 | 2 | 5 |
| 2024 | 5 | 5 | 10 |
| 2025 | 5 | 0 | 5 |
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click here.
Below are the most recent publications written about "tau Proteins" by people in Profiles.
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Computational and functional prioritization identifies genes that rescue behavior and reduce tau protein in fly and human cell models of Alzheimer disease. Am J Hum Genet. 2025 May 01; 112(5):1081-1096.
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Glucose uptake in pigment glia suppresses Tau-induced inflammation and photoreceptor degeneration. Dis Model Mech. 2025 Apr 01; 18(4).
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Electrostatic Effects on Tau Nanocondensates. Biomolecules. 2025 Mar 12; 15(3).
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Relationships between hypometabolism and both ?-amyloid and tau PET in corticobasal syndrome. Alzheimers Dement. 2025 Mar; 21(3):e70018.
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Tau Oligomers Resist Phase Separation. Biomolecules. 2025 Feb 26; 15(3).
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In vivo hyperphosphorylation of tau is associated with synaptic loss and behavioral abnormalities in the absence of tau seeds. Nat Neurosci. 2025 Feb; 28(2):293-307.
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The POINTER Imaging baseline cohort: Associations between multimodal neuroimaging biomarkers, cardiovascular health, and cognition. Alzheimers Dement. 2025 Jan; 21(1):e14399.
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APOE4 and age affect the brain entorhinal cortex structure and blood arachidonic acid and docosahexaenoic acid levels after mild TBI. Sci Rep. 2024 11 25; 14(1):29150.
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Tau filaments are tethered within brain extracellular vesicles in Alzheimer's disease. Nat Neurosci. 2025 Jan; 28(1):40-48.
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TYK2 regulates tau levels, phosphorylation and aggregation in a tauopathy mouse model. Nat Neurosci. 2024 Dec; 27(12):2417-2429.