"tau Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins constitute several isoforms and play an important role in the assembly of tubulin monomers into microtubules and in maintaining the cytoskeleton and axonal transport. Aggregation of specific sets of tau proteins in filamentous inclusions is the common feature of intraneuronal and glial fibrillar lesions (NEUROFIBRILLARY TANGLES; NEUROPIL THREADS) in numerous neurodegenerative disorders (ALZHEIMER DISEASE; TAUOPATHIES).
| Descriptor ID |
D016875
|
| MeSH Number(s) |
D12.776.220.600.450.510 D12.776.631.560.510
|
| Concept/Terms |
tau Proteins- tau Proteins
- Proteins, tau
- tau Protein
- Protein, tau
|
Below are MeSH descriptors whose meaning is more general than "tau Proteins".
Below are MeSH descriptors whose meaning is more specific than "tau Proteins".
This graph shows the total number of publications written about "tau Proteins" by people in this website by year, and whether "tau Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2001 | 3 | 2 | 5 |
| 2002 | 1 | 1 | 2 |
| 2003 | 2 | 1 | 3 |
| 2004 | 0 | 1 | 1 |
| 2005 | 3 | 1 | 4 |
| 2006 | 3 | 3 | 6 |
| 2007 | 2 | 1 | 3 |
| 2008 | 2 | 3 | 5 |
| 2009 | 2 | 0 | 2 |
| 2010 | 4 | 1 | 5 |
| 2011 | 5 | 2 | 7 |
| 2012 | 3 | 2 | 5 |
| 2013 | 7 | 1 | 8 |
| 2014 | 8 | 1 | 9 |
| 2015 | 2 | 2 | 4 |
| 2016 | 7 | 2 | 9 |
| 2017 | 2 | 1 | 3 |
| 2018 | 11 | 1 | 12 |
| 2019 | 4 | 2 | 6 |
| 2020 | 4 | 4 | 8 |
| 2021 | 4 | 1 | 5 |
| 2022 | 0 | 4 | 4 |
| 2023 | 2 | 4 | 6 |
| 2024 | 7 | 5 | 12 |
| 2025 | 10 | 4 | 14 |
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Below are the most recent publications written about "tau Proteins" by people in Profiles.
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Altered patterning of neural activity in a neuropathology. Sci Rep. 2025 Jul 16; 15(1):25881.
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Distinct 11C-ER176 PET Neuroinflammatory Profiles and Tau Colocalization in Progressive Apraxia of Speech With and Without Parkinson-plus Syndrome. Clin Nucl Med. 2025 Aug 01; 50(8):731-742.
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Linked alterations in structure and autoimmunity biomarkers in remote mild-to-moderate TBI: A multi-modal brain imaging study. Neuroimage Clin. 2025; 47:103838.
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Generation of human induced pluripotent stem cell line from a familial Alzheimer's disease patient carrying missense mutations in PSEN1 and MAPT genes. Stem Cell Res. 2025 Sep; 87:103759.
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Sensing Protein Structural Transitions with Microfluidic Modulation Infrared Spectroscopy. Biosensors (Basel). 2025 Jun 13; 15(6).
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Rewired m6A of promoter antisense RNAs in Alzheimer's disease regulates neuronal genes in 3D nucleome. Nat Commun. 2025 Jun 06; 16(1):5251.
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Distinct systemic impacts of A?42 and Tau revealed by whole-organism snRNA-seq. Neuron. 2025 Jul 09; 113(13):2065-2082.e8.
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Tau depletion diminishes vascular amyloid-related deficits in a mouse model of cerebral amyloid angiopathy. Alzheimers Dement. 2025 May; 21(5):e70238.
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Subcellular functions of tau mediate repair response and synaptic homeostasis in injury. Mol Psychiatry. 2025 Oct; 30(10):4460-4472.
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Computational and functional prioritization identifies genes that rescue behavior and reduce tau protein in fly and human cell models of Alzheimer disease. Am J Hum Genet. 2025 May 01; 112(5):1081-1096.