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GEORGE JACKSON

TitleSenior Faculty
InstitutionBaylor College of Medicine
DepartmentDepartment of Neurology
Address7200 CAMBRIDGE
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    Collapse Research 
    Collapse research activities and funding
    R01NS046489     (JACKSON, GEORGE R)Jul 15, 2004 - Jun 30, 2009
    NIH/NINDS
    Molecular Genetics of Tau-Associated Neurodegeneration
    Role: Principal Investigator
    K08NS002116     (JACKSON, GEORGE R)Jul 5, 1999 - Aug 31, 2004
    NIH/NINDS
    Molecular Genetics of Polyglutamine-Induced Degeneration
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Malek J, Levchenko A, Robinson JO, Fong J, Lin CR, Jackson GR, Blumenthal-Barby J, Shulman JM, McGuire AL. Dilemmas in diagnosing Alzheimer's disease: The peril and promise of self-fulfilling prophecies. J Alzheimers Dis. 2025 Jun; 105(3):736-739. PMID: 40255038.
      Citations:    Fields:    Translation:Humans
    2. Newsome MR, Martindale SL, Davenport N, Dennis EL, Diaz M, Esopenko C, Hodges C, Jackson GR, Liu Q, Kenney K, Mayer AR, Rowland JA, Scheibel RS, Steinberg JL, Taylor BA, Tate DF, Werner JK, Walker WC, Wilde EA. Subcortical functional connectivity and its association with walking performance following deployment related mild TBI. Front Neurol. 2023; 14:1276437. PMID: 38156092; PMCID: PMC10752967.
      Citations:    
    3. Yusuff T, Chang YC, Sang TK, Jackson GR, Chatterjee S. Codon-optimized TDP-43 mediates neurodegeneration in a Drosophila model of ALS/FTLD. Front Genet. 2023; 14:881638. PMID: 36968586; PMCID: PMC10034021.
      Citations:    
    4. Troyanskaya M, Pastorek NJ, Jamal F, Jackson GR, Sarwar AI, Wilde EA, Scheibel RS. A pilot study of olfactory function in veterans with a history of deployment-related mild traumatic brain injury. Neurocase. 2022 12; 28(6):459-466. PMID: 36576237.
      Citations:    Fields:    Translation:Humans
    5. Shah C, Jackson GR, Sarwar AI, Mandava P, Jamal F. Treatment Patterns in Essential Tremor: A Retrospective Analysis. Tremor Other Hyperkinet Mov (N Y). 2022; 12:10. PMID: 35415009; PMCID: PMC8954883.
      Citations:    Fields:    Translation:Humans
    6. Derry PJ, Hegde ML, Jackson GR, Kayed R, Tour JM, Tsai AL, Kent TA. Revisiting the intersection of amyloid, pathologically modified tau and iron in Alzheimer's disease from a ferroptosis perspective. Prog Neurobiol. 2020 01; 184:101716. PMID: 31604111; PMCID: PMC7850812.
      Citations: 37     Fields:    Translation:HumansAnimals
    7. Chatterjee S, Ambegaokar SS, Jackson GR, Mudher A. Insulin-Mediated Changes in Tau Hyperphosphorylation and Autophagy in a Drosophila Model of Tauopathy and Neuroblastoma Cells. Front Neurosci. 2019; 13:801. PMID: 31427921; PMCID: PMC6688711.
      Citations: 5     
    8. Jackson GR. Lifestyles of a Toxic Twosome: A Novel Tau Strain Induced by a-Synuclein Oligomers. Biol Psychiatry. 2018 10 01; 84(7):472-473. PMID: 30176989.
      Citations: 1     Fields:    
    9. Chouhan AK, Guo C, Hsieh YC, Ye H, Senturk M, Zuo Z, Li Y, Chatterjee S, Botas J, Jackson GR, Bellen HJ, Shulman JM. Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease. Acta Neuropathol Commun. 2016 06 23; 4(1):62. PMID: 27338814; PMCID: PMC4918017.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    10. Newsome MR, Mayer AR, Lin X, Troyanskaya M, Jackson GR, Scheibel RS, Walder A, Sathiyaraj A, Wilde EA, Mukhi S, Taylor BA, Levin HS. Chronic Effects of Blast-Related TBI on Subcortical Functional Connectivity in Veterans. J Int Neuropsychol Soc. 2016 07; 22(6):631-42. PMID: 27264731.
      Citations: 6     Fields:    Translation:Humans
    11. Iyer J, Wang Q, Le T, Pizzo L, Ambegaokar SS, Imai Y, Srivastava A, Mardon G, Artero R, Jackson GR, Isaacs AM, Partridge L, Lu B, Kumar JP, Girirajan S, Gr?nke S, Trois? BL. Quantitative Assessment of Eye Phenotypes for Functional Genetic Studies Using Drosophila melanogaster. G3 (Bethesda). 2016 05 03; 6(5):1427-37. PMID: 26994292; PMCID: PMC4856093.
      Citations: 19     Fields:    Translation:Animals
    12. Bryant MS, Jackson GR, Hou JG, Protas EJ. Treadmill exercise tests in persons with Parkinson's disease: responses and disease severity. Aging Clin Exp Res. 2016 Oct; 28(5):1009-14. PMID: 26590841.
      Citations: 4     Fields:    Translation:Humans
    13. Bryant MS, Workman CD, Jackson GR. Multidirectional walk test in individuals with Parkinson's disease: a validity study. Int J Rehabil Res. 2015 Mar; 38(1):88-91. PMID: 25371075.
      Citations: 4     Fields:    Translation:Humans
    14. Sengupta U, Castillo-Carranza DL, Lasagna-Reeves CA, Gerson JE, Paulucci-Holthauzen AA, Krishnamurthy S, Farhed M, Jackson GR, Kayed R, Guerrero-Mu?oz MJ. Pathological interface between oligomeric alpha-synuclein and tau in synucleinopathies. Biol Psychiatry. 2015 Nov 15; 78(10):672-83. PMID: 25676491.
      Citations: 72     Fields:    Translation:HumansCells
    15. Castillo-Carranza DL, Krishnamurthy S, Paulucci-Holthauzen AA, Sengupta U, Lasagna-Reeves CA, Ahmad Y, Jackson GR, Kayed R, Guerrero-Mu?oz MJ. Amyloid-? oligomers as a template for secondary amyloidosis in Alzheimer's disease. Neurobiol Dis. 2014 Nov; 71:14-23. PMID: 25134727.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    16. Lasagna-Reeves CA, Sengupta U, Castillo-Carranza D, Gerson JE, Guerrero-Munoz M, Troncoso JC, Jackson GR, Kayed R. The formation of tau pore-like structures is prevalent and cell specific: possible implications for the disease phenotypes. Acta Neuropathol Commun. 2014 May 29; 2:56. PMID: 24887264; PMCID: PMC4231072.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    17. Yassin AM, Shroff S, Patel SD, Paker AM, Berman MA, Jackson GR. Hemichorea in a patient with diabetic ketoacidosis. J Neurol Sci. 2014 Jul 15; 342(1-2):189-91. PMID: 24857350.
      Citations: 4     Fields:    Translation:Humans
    18. Castillo-Carranza DL, Sengupta U, Lasagna-Reeves CA, Gerson JE, Singh G, Estes DM, Barrett AD, Dineley KT, Jackson GR, Kayed R, Guerrero-Mu?oz MJ. Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles. J Neurosci. 2014 Mar 19; 34(12):4260-72. PMID: 24647946; PMCID: PMC6608097.
      Citations: 125     Fields:    Translation:AnimalsCells
    19. Bakhoum MF, Bakhoum CY, Ding Z, Carlton SM, Campbell GA, Jackson GR. Evidence for autophagic gridlock in aging and neurodegeneration. Transl Res. 2014 Jul; 164(1):1-12. PMID: 24561013.
      Citations: 4     Fields:    Translation:HumansAnimals
    20. Roy B, Jackson GR. Interactions between Tau and a-synuclein augment neurotoxicity in a Drosophila model of Parkinson's disease. Hum Mol Genet. 2014 Jun 01; 23(11):3008-23. PMID: 24430504; PMCID: PMC4014195.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    21. Choksi DK, Roy B, Chatterjee S, Yusuff T, Bakhoum MF, Sengupta U, Ambegaokar S, Kayed R, Jackson GR. TDP-43 Phosphorylation by casein kinase Ie promotes oligomerization and enhances toxicity in vivo. Hum Mol Genet. 2014 Feb 15; 23(4):1025-35. PMID: 24105464.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    22. Wightman PJ, Jackson GR, Dipple KM. Disruption of glycerol metabolism by RNAi targeting of genes encoding glycerol kinase results in a range of phenotype severity in Drosophila. PLoS One. 2013; 8(9):e71664. PMID: 24039719; PMCID: PMC3765373.
      Citations: 1     Fields:    Translation:HumansAnimals
    23. Hawkins BE, Krishnamurthy S, Castillo-Carranza DL, Sengupta U, Prough DS, Jackson GR, DeWitt DS, Kayed R. Rapid accumulation of endogenous tau oligomers in a rat model of traumatic brain injury: possible link between traumatic brain injury and sporadic tauopathies. J Biol Chem. 2013 Jun 07; 288(23):17042-17050. PMID: 23632019; PMCID: PMC3675635.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    24. Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Guerrero-Munoz MJ, Kiritoshi T, Neugebauer V, Jackson GR, Kayed R. Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau. Sci Rep. 2012; 2:700. PMID: 23050084; PMCID: PMC3463004.
      Citations: 206     Fields:    Translation:HumansAnimalsCells
    25. Ambegaokar SS, Jackson GR. The downward spiral of tau and autolysosomes: a new hypothesis in neurodegeneration. Autophagy. 2012 Jul 01; 8(7):1144-5. PMID: 22635052; PMCID: PMC3429552.
      Citations: 10     Fields:    Translation:HumansAnimals
    26. Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NY, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ET, Bartholomew CR, Bassham DC, Bast RC, Batoko H, Bay BH, Beau I, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, Bortoluci KR, Bossis I, Bourquin JP, Boya P, Bozhkov PV, Brady NR, Brancolini C, Brech A, Brenman JE, Brennand A, Bresnick EH, Brest P, Bridges D, Bristol ML, Brookes PS, Brown EJ, Brumell JH, Brunetti-Pierri N, Brunk UT, Bulman DE, Bultman SJ, Bultynck G, Burbulla LF, Bursch W, Butchar JP, Buzgariu W, Bydlowski SP, Cadwell K, Cai D, Cai J, Cai Q, Calabretta B, Calvo-Garrido J, Camougrand N, Campanella M, Campos-Salinas J, Candi E, Cao L, Caplan AB, Carding SR, Cardoso SM, Carew JS, Carlin CR, Carmignac V, Carneiro LA, Carra S, Caruso RA, Casari G, Casas C, Castino R, Cebollero E, Cecconi F, Celli J, Chaachouay H, Chae HJ, Chai CY, Chan DC, Chan EY, Chang RC, Che CM, Chen CC, Chen GC, Chen GQ, Chen M, Chen Q, Chen SS, Chen W, Chen X, Chen X, Chen X, Chen YG, Chen Y, Chen Y, Chen YJ, Chen Z, Cheng A, Cheng CH, Cheng Y, Cheong H, Cheong JH, Cherry S, Chess-Williams R, Cheung ZH, Chevet E, Chiang HL, Chiarelli R, Chiba T, Chin LS, Chiou SH, Chisari FV, Cho CH, Cho DH, Choi AM, Choi D, Choi KS, Choi ME, Chouaib S, Choubey D, Choubey V, Chu CT, Chuang TH, Chueh SH, Chun T, Chwae YJ, Chye ML, Ciarcia R, Ciriolo MR, Clague MJ, Clark RS, Clarke PG, Clarke R, Codogno P, Coller HA, Comincini S, Condello M, Condorelli F, Cookson MR, Coombs GH, Coppens I, Corbalan R, Cossart P, Costelli P, Costes S, Coto-Montes A, Couve E, Coxon FP, Cregg JM, Cuervo AM, Cullen JJ, Czaja MJ, D'Amelio M, Darfeuille-Michaud A, Davids LM, Davies FE, De Felici M, de Groot JF, de Haan CA, De Martino L, De Milito A, De Tata V, Debnath J, Degterev A, Dehay B, Delbridge LM, Demarchi F, Deng YZ, Dent P, Denton D, Deretic V, Desai SD, Devenish RJ, Di Gioacchino M, Di Paolo G, Di Pietro C, Diaz-Meco MT, Diaz-Nido J, Dikic I, Dinesh-Kumar SP, Ding WX, Distelhorst CW, Diwan A, Djavaheri-Mergny M, Dokudovskaya S, Dong Z, Dorsey FC, Dosenko V, Dowling JJ, Doxsey S, Drew ME, Duan Q, Duchosal MA, Duff K, Dugail I, Durbeej M, Duszenko M, Edelstein CL, Edinger AL, Egea G, Eichinger L, Eissa NT, Ekmekcioglu S, El-Deiry WS, Elazar Z, Elgendy M, Ellerby LM, Eng KE, Engelbrecht AM, Engelender S, Erenpreisa J, Escalante R, Esclatine A, Eskelinen EL, Espert L, Espina V, Fan H, Fan J, Fan QW, Fan Z, Fang S, Fang Y, Fanto M, Fanzani A, Farkas T, Faure M, Fechheimer M, Feng CG, Feng J, Feng Q, Feng Y, Feuer R, Figueiredo-Pereira ME, Fimia GM, Fingar DC, Finkbeiner S, Finkel T, Finley KD, Fiorito F, Fisher EA, Fisher PB, Flajolet M, Florez-McClure ML, Florio S, Fon EA, Fornai F, Fortunato F, Fotedar R, Fowler DH, Fox HS, Franco R, Frankel LB, Fransen M, Fueyo J, Fujii J, Fujisaki K, Fujita E, Fukuda M, Furukawa RH, Gaestel M, Gailly P, Gajewska M, Galliot B, Galy V, Ganesh S, Ganetzky B, Ganley IG, Gao FB, Gao GF, Gao J, Garcia L, Garcia-Manero G, Garcia-Marcos M, Garmyn M, Gartel AL, Gatti E, Gautel M, Gawriluk TR, Gegg ME, Geng J, Germain M, Gestwicki JE, Gewirtz DA, Ghavami S, Ghosh P, Giammarioli AM, Giatromanolaki AN, Gibson SB, Gilkerson RW, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012 Apr; 8(4):445-544. PMID: 22966490; PMCID: PMC3404883.
      Citations: 1751     Fields:    Translation:HumansAnimals
    27. Wightman PJ, Jackson GR, Dipple KM. Glycerol hypersensitivity in a Drosophila model for glycerol kinase deficiency is affected by mutations in eye pigmentation genes. PLoS One. 2012; 7(3):e31779. PMID: 22427807; PMCID: PMC3302884.
      Citations: 3     Fields:    Translation:Animals
    28. Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Sarmiento J, Troncoso J, Jackson GR, Kayed R. Identification of oligomers at early stages of tau aggregation in Alzheimer's disease. FASEB J. 2012 May; 26(5):1946-59. PMID: 22253473; PMCID: PMC4046102.
      Citations: 204     Fields:    Translation:HumansCells
    29. Jackson GR, Scott IU, Quillen DA, Walter LE, Gardner TW. Inner retinal visual dysfunction is a sensitive marker of non-proliferative diabetic retinopathy. Br J Ophthalmol. 2012 May; 96(5):699-703. PMID: 22174096.
      Citations: 56     Fields:    Translation:HumansCells
    30. Clos AL, Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Jackson GR, Kelly B, Beachkofsky TM, Kayed R. Formation of immunoglobulin light chain amyloid oligomers in primary cutaneous nodular amyloidosis. Br J Dermatol. 2011 Dec; 165(6):1349-54. PMID: 21729025.
      Citations: 4     Fields:    Translation:HumansCells
    31. Ambegaokar SS, Jackson GR. Functional genomic screen and network analysis reveal novel modifiers of tauopathy dissociated from tau phosphorylation. Hum Mol Genet. 2011 Dec 15; 20(24):4947-77. PMID: 21949350; PMCID: PMC3221533.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    32. Lasagna-Reeves CA, Castillo-Carranza DL, Jackson GR, Kayed R. Tau oligomers as potential targets for immunotherapy for Alzheimer's disease and tauopathies. Curr Alzheimer Res. 2011 Sep; 8(6):659-65. PMID: 21605039.
      Citations: 33     Fields:    Translation:Humans
    33. Clos AL, Lasagna-Reeves CA, Kelly B, Wagner R, Wilkerson M, Jackson GR, Kayed R. Role of oligomers in the amyloidogenesis of primary cutaneous amyloidosis. J Am Acad Dermatol. 2011 Nov; 65(5):1023-31. PMID: 21669474.
      Citations: 3     Fields:    Translation:HumansCells
    34. Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Clos AL, Jackson GR, Kayed R. Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice. Mol Neurodegener. 2011 Jun 06; 6:39. PMID: 21645391; PMCID: PMC3224595.
      Citations: 219     Fields:    
    35. Kayed R, Jackson GR, Estes DM, Barrett AD. Alzheimers disease: review of emerging treatment role for intravenous immunoglobulins. J Cent Nerv Syst Dis. 2011; 3:67-73. PMID: 23861639; PMCID: PMC3663607.
      Citations: 3     
    36. Chang YC, Hung WT, Chang YC, Chang HC, Wu CL, Chiang AS, Jackson GR, Sang TK. Pathogenic VCP/TER94 alleles are dominant actives and contribute to neurodegeneration by altering cellular ATP level in a Drosophila IBMPFD model. PLoS Genet. 2011 Feb 03; 7(2):e1001288. PMID: 21304887; PMCID: PMC3033380.
      Citations: 27     Fields:    Translation:HumansAnimals
    37. Bakhoum MF, Jackson GR. Demise of the flies: why Drosophila models still matter. Prog Mol Biol Transl Sci. 2011; 100:483-98. PMID: 21377634.
      Citations: 2     Fields:    Translation:HumansAnimals
    38. Lasagna-Reeves CA, Castillo-Carranza DL, Guerrero-Muoz MJ, Jackson GR, Kayed R. Preparation and characterization of neurotoxic tau oligomers. Biochemistry. 2010 Nov 30; 49(47):10039-41. PMID: 21047142.
      Citations: 159     Fields:    Translation:HumansCells
    39. Clos AL, Lasagna-Reeves CA, Wagner R, Kelly B, Jackson GR, Kayed R. Therapeutic removal of amyloid deposits in cutaneous amyloidosis by localised intra-lesional injections of anti-amyloid antibodies. Exp Dermatol. 2010 Oct; 19(10):904-11. PMID: 20626464.
      Citations: 3     Fields:    Translation:HumansAnimals
    40. Lasagna-Reeves CA, Clos AL, Midoro-Hiriuti T, Goldblum RM, Jackson GR, Kayed R. Inhaled insulin forms toxic pulmonary amyloid aggregates. Endocrinology. 2010 Oct; 151(10):4717-24. PMID: 20685871.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    41. Ambegaokar SS, Jackson GR. Interaction between eye pigment genes and tau-induced neurodegeneration in Drosophila melanogaster. Genetics. 2010 Sep; 186(1):435-42. PMID: 20592261; PMCID: PMC2940309.
      Citations: 10     Fields:    Translation:AnimalsCells
    42. Ambegaokar SS, Roy B, Jackson GR. Neurodegenerative models in Drosophila: polyglutamine disorders, Parkinson disease, and amyotrophic lateral sclerosis. Neurobiol Dis. 2010 Oct; 40(1):29-39. PMID: 20561920; PMCID: PMC2926295.
      Citations: 26     Fields:    Translation:HumansAnimals
    43. Barrett AD, Kayed R, Jackson GR, Cunningham KA. New vaccine development for chronic brain disease. Neuropsychopharmacology. 2010 Jan; 35(1):354. PMID: 20010720; PMCID: PMC3055416.
      Citations: 2     Fields:    Translation:HumansAnimalsPHPublic Health
    44. Kayed R, Jackson GR. Prefilament tau species as potential targets for immunotherapy for Alzheimer disease and related disorders. Curr Opin Immunol. 2009 Jun; 21(3):359-63. PMID: 19482462.
      Citations: 21     Fields:    Translation:HumansCells
    45. Lu XH, Fleming SM, Meurers B, Ackerson LC, Mortazavi F, Lo V, Hernandez D, Sulzer D, Jackson GR, Maidment NT, Chesselet MF, Yang XW. Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein. J Neurosci. 2009 Feb 18; 29(7):1962-76. PMID: 19228951; PMCID: PMC2803056.
      Citations: 75     Fields:    Translation:HumansAnimalsCells
    46. Chatterjee S, Sang TK, Lawless GM, Jackson GR. Dissociation of tau toxicity and phosphorylation: role of GSK-3beta, MARK and Cdk5 in a Drosophila model. Hum Mol Genet. 2009 Jan 01; 18(1):164-77. PMID: 18930955; PMCID: PMC2644648.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    47. Schaffer BA, Bertram L, Miller BL, Mullin K, Weintraub S, Johnson N, Bigio EH, Mesulam M, Wiedau-Pazos M, Jackson GR, Cummings JL, Cantor RM, Levey AI, Tanzi RE, Geschwind DH. Association of GSK3B with Alzheimer disease and frontotemporal dementia. Arch Neurol. 2008 Oct; 65(10):1368-74. PMID: 18852354; PMCID: PMC2841136.
      Citations: 33     Fields:    Translation:HumansCells
    48. Ratnaparkhi A, Lawless GM, Schweizer FE, Golshani P, Jackson GR. A Drosophila model of ALS: human ALS-associated mutation in VAP33A suggests a dominant negative mechanism. PLoS One. 2008 Jun 04; 3(6):e2334. PMID: 18523548; PMCID: PMC2390852.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    49. Jackson GR. Guide to understanding Drosophila models of neurodegenerative diseases. PLoS Biol. 2008 Feb; 6(2):e53. PMID: 18303955; PMCID: PMC2253643.
      Citations: 5     Fields:    Translation:HumansAnimals
    50. Sang TK, Chang HY, Lawless GM, Ratnaparkhi A, Mee L, Ackerson LC, Maidment NT, Krantz DE, Jackson GR. A Drosophila model of mutant human parkin-induced toxicity demonstrates selective loss of dopaminergic neurons and dependence on cellular dopamine. J Neurosci. 2007 Jan 31; 27(5):981-92. PMID: 17267552; PMCID: PMC6673194.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    51. Sengupta S, Horowitz PM, Karsten SL, Jackson GR, Geschwind DH, Fu Y, Berry RW, Binder LI. Degradation of tau protein by puromycin-sensitive aminopeptidase in vitro. Biochemistry. 2006 Dec 19; 45(50):15111-9. PMID: 17154549.
      Citations: 38     Fields:    Translation:HumansCells
    52. Slepko N, Bhattacharyya AM, Jackson GR, Steffan JS, Marsh JL, Thompson LM, Wetzel R. Normal-repeat-length polyglutamine peptides accelerate aggregation nucleation and cytotoxicity of expanded polyglutamine proteins. Proc Natl Acad Sci U S A. 2006 Sep 26; 103(39):14367-72. PMID: 16980414; PMCID: PMC1599969.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    53. Karsten SL, Sang TK, Gehman LT, Chatterjee S, Liu J, Lawless GM, Sengupta S, Berry RW, Pomakian J, Oh HS, Schulz C, Hui KS, Wiedau-Pazos M, Vinters HV, Binder LI, Geschwind DH, Jackson GR. A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration. Neuron. 2006 Sep 07; 51(5):549-60. PMID: 16950154.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    54. Sang TK, Jackson GR. Drosophila models of neurodegenerative disease. NeuroRx. 2005 Jul; 2(3):438-46. PMID: 16389307; PMCID: PMC1144487.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    55. Mee L, Honkala H, Kopra O, Vesa J, Sang TK, Jackson GR, Salonen R, Peltonen L, Finnil? S, Visap?? I, Kestil? M. Hydrolethalus syndrome is caused by a missense mutation in a novel gene HYLS1. Hum Mol Genet. 2005 Jun 01; 14(11):1475-88. PMID: 15843405.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    56. Sang TK, Li C, Liu W, Rodriguez A, Abrams JM, Zipursky SL, Jackson GR. Inactivation of Drosophila Apaf-1 related killer suppresses formation of polyglutamine aggregates and blocks polyglutamine pathogenesis. Hum Mol Genet. 2005 Feb 01; 14(3):357-72. PMID: 15590702.
      Citations: 28     Fields:    Translation:HumansAnimals
    57. Jackson GR, Wiedau-Pazos M, Sang TK, Wagle N, Brown CA, Massachi S, Geschwind DH. Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila. Neuron. 2002 May 16; 34(4):509-19. PMID: 12062036.
      Citations: 209     Fields:    Translation:HumansAnimalsCells
    58. Steffan JS, Bodai L, Pallos J, Poelman M, McCampbell A, Apostol BL, Kazantsev A, Schmidt E, Zhu YZ, Greenwald M, Kurokawa R, Housman DE, Jackson GR, Marsh JL, Thompson LM. Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila. Nature. 2001 Oct 18; 413(6857):739-43. PMID: 11607033.
      Citations: 450     Fields:    Translation:AnimalsCells
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