"ELAV Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of RRM PROTEINS that are homologues of ELAV protein, Drosophila. They were initially identified in humans as the targets of autoantibodies in patients with PARANEOPLASTIC ENCEPHALOMYELITIS. They regulate GENE EXPRESSION at the post-transcriptional level.
| Descriptor ID |
D051959
|
| MeSH Number(s) |
D12.776.157.725.813.500 D12.776.631.520 D12.776.664.962.813.500
|
| Concept/Terms |
ELAV Proteins- ELAV Proteins
- Proteins, ELAV
- ELAV Protein
- Protein, ELAV
- Hu Antigens
- Antigens, Hu
- Embryonic Lethal, Abnormal Vision-Like Proteins
- Embryonic Lethal, Abnormal Vision Like Proteins
- Hu Paraneoplastic Encephalomyelitis Antigens
|
Below are MeSH descriptors whose meaning is more general than "ELAV Proteins".
Below are MeSH descriptors whose meaning is more specific than "ELAV Proteins".
This graph shows the total number of publications written about "ELAV Proteins" by people in this website by year, and whether "ELAV Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 3 | 3 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2014 | 2 | 0 | 2 |
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Below are the most recent publications written about "ELAV Proteins" by people in Profiles.
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A single element in the 3'UTR of the apical sodium-dependent bile acid transporter controls both stabilization and destabilization of mRNA. Biochem J. 2014 Sep 15; 462(3):547-53.
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The role of HuR in the post-transcriptional regulation of interleukin-3 in T cells. PLoS One. 2014; 9(3):e92457.
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dCK expression correlates with 5-fluorouracil efficacy and HuR cytoplasmic expression in pancreatic cancer: a dual-institutional follow-up with the RTOG 9704 trial. Cancer Biol Ther. 2014 Jun 01; 15(6):688-98.
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The prolyl isomerase pin1 regulates mRNA levels of genes with short half-lives by targeting specific RNA binding proteins. PLoS One. 2014; 9(1):e85427.
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Predictive and prognostic significance of cytoplasmic expression of ELAV-like protein HuR in invasive breast cancer treated with neoadjuvant chemotherapy. Breast Cancer Res Treat. 2013 Sep; 141(2):213-24.
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miR-195 competes with HuR to modulate stim1 mRNA stability and regulate cell migration. Nucleic Acids Res. 2013 Sep; 41(16):7905-19.
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Role of transcription factor Sp1 and RNA binding protein HuR in the downregulation of Dr+ Escherichia coli receptor protein decay accelerating factor (DAF or CD55) by nitric oxide. FEBS J. 2013 Feb; 280(3):840-54.
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Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability. Neuron. 2012 Sep 20; 75(6):1067-80.
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Hu antigen R and tristetraprolin: counter-regulators of rat apical sodium-dependent bile acid transporter by way of effects on messenger RNA stability. Hepatology. 2011 Oct; 54(4):1371-8.
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Paraneoplastic upbeat nystagmus. Neurology. 2011 Aug 16; 77(7):691-3.