Heterogeneous-Nuclear Ribonucleoproteins
"Heterogeneous-Nuclear Ribonucleoproteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of ribonucleoproteins that were originally found as proteins bound to nascent RNA transcripts in the form of ribonucleoprotein particles. Although considered ribonucleoproteins they are primarily classified by their protein component. They are involved in a variety of processes such as packaging of RNA and RNA TRANSPORT within the nucleus. A subset of heterogeneous-nuclear ribonucleoproteins are involved in additional functions such as nucleocytoplasmic transport (ACTIVE TRANSPORT, CELL NUCLEUS) of RNA and mRNA stability in the CYTOPLASM.
| Descriptor ID |
D034441
|
| MeSH Number(s) |
D12.776.157.725.813.750 D12.776.664.962.813.750
|
| Concept/Terms |
Heterogeneous-Nuclear Ribonucleoproteins- Heterogeneous-Nuclear Ribonucleoproteins
- Heterogeneous Nuclear Ribonucleoproteins
- Ribonucleoproteins, Heterogeneous-Nuclear
- hnRNP
- Informofer
- Heterogeneous Nuclear Ribonucleoprotein
- Nuclear Ribonucleoprotein, Heterogeneous
- Ribonucleoprotein, Heterogeneous Nuclear
|
Below are MeSH descriptors whose meaning is more general than "Heterogeneous-Nuclear Ribonucleoproteins".
Below are MeSH descriptors whose meaning is more specific than "Heterogeneous-Nuclear Ribonucleoproteins".
This graph shows the total number of publications written about "Heterogeneous-Nuclear Ribonucleoproteins" by people in this website by year, and whether "Heterogeneous-Nuclear Ribonucleoproteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2015 | 2 | 1 | 3 |
| 2016 | 2 | 0 | 2 |
| 2018 | 2 | 1 | 3 |
| 2020 | 0 | 1 | 1 |
| 2021 | 2 | 0 | 2 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Heterogeneous-Nuclear Ribonucleoproteins" by people in Profiles.
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An anciently diverged family of RNA binding proteins maintain correct splicing of a class of ultra-long exons through cryptic splice site repression. Elife. 2024 Oct 02; 12.
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Insight into the mechanism of AML del(9q) progression: hnRNP K targets the myeloid master regulators CEBPA (C/EBPa) and SPI1 (PU.1). Biochim Biophys Acta Gene Regul Mech. 2024 Mar; 1867(1):195004.
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Neurodevelopmental deficits and cell-type-specific transcriptomic perturbations in a mouse model of HNRNPU haploinsufficiency. PLoS Genet. 2023 Oct; 19(10):e1010952.
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A novel LINC00478 serves as a tumor suppressor in endometrial carcinoma progression. J Cancer Res Clin Oncol. 2023 Nov; 149(16):14927-14940.
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The ubiquitin E3 ligase ARIH1 regulates hnRNP E1 protein stability, EMT and breast cancer progression. Oncogene. 2022 03; 41(12):1679-1690.
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Further evidence for de novo variants in SYNCRIP as the cause of a neurodevelopmental disorder. Hum Mutat. 2021 09; 42(9):1094-1100.
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Dynamics of alternative splicing during somatic cell reprogramming reveals functions for RNA-binding proteins CPSF3, hnRNP UL1, and TIA1. Genome Biol. 2021 06 03; 22(1):171.
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Rare deleterious mutations of HNRNP genes result in shared neurodevelopmental disorders. Genome Med. 2021 04 19; 13(1):63.
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Perfluorooctanoic acid (PFOA) or perfluorooctane sulfonate (PFOS) and DNA methylation in newborn dried blood spots in the Upstate KIDS cohort. Environ Res. 2021 03; 194:110668.
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Regulation of Notch Signaling in Drosophila melanogaster: The Role of the Heterogeneous Nuclear Ribonucleoprotein Hrp48 and Deltex. Adv Exp Med Biol. 2020; 1227:95-105.