"CELF Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of RRM proteins which contain two N-terminal RNA RECOGNITION MOTIF (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 amino acids between the second and third RRM domains. They regulate pre-mRNA ALTERNATIVE SPLICING and also function in RNA EDITING and PROTEIN BIOSYNTHESIS.
| Descriptor ID |
D000067878
|
| MeSH Number(s) |
D12.776.157.725.813.250 D12.776.664.962.813.250
|
| Concept/Terms |
CELF Proteins- CELF Proteins
- Proteins, CELF
- BRUNOL Proteins
- Proteins, BRUNOL
- CUGBP, Elav-Like Family Member Proteins
- CUGBP, Elav Like Family Member Proteins
- CUG Triplet Repeat, RNA-Binding Proteins
- CUG Triplet Repeat, RNA Binding Proteins
- CUG-BP Proteins
- CUG BP Proteins
- Proteins, CUG-BP
- CUGBP Proteins
- Proteins, CUGBP
- Bruno-Like Family Member Proteins
- Bruno Like Family Member Proteins
|
Below are MeSH descriptors whose meaning is more general than "CELF Proteins".
Below are MeSH descriptors whose meaning is more specific than "CELF Proteins".
This graph shows the total number of publications written about "CELF Proteins" by people in this website by year, and whether "CELF Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "CELF Proteins" by people in Profiles.
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Loss of CELF2 promotes skin tumorigenesis and increases drug resistance. Int J Dermatol. 2025 Jan; 64(1):101-110.
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CELF4 Variant and Anthracycline-Related Cardiomyopathy: A Children's Oncology Group Genome-Wide Association Study. J Clin Oncol. 2016 Mar 10; 34(8):863-70.
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Antagonistic regulation of mRNA expression and splicing by CELF and MBNL proteins. Genome Res. 2015 Jun; 25(6):858-71.
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Cardiac tissue-specific repression of CELF activity disrupts alternative splicing and causes cardiomyopathy. Mol Cell Biol. 2005 Jul; 25(14):6267-78.
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Cardiac elav-type RNA-binding protein (ETR-3) binds to RNA CUG repeats expanded in myotonic dystrophy. Hum Mol Genet. 1999 Jan; 8(1):53-60.