"Allopurinol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A XANTHINE OXIDASE inhibitor that decreases URIC ACID production. It also acts as an antimetabolite on some simpler organisms.
| Descriptor ID |
D000493
|
| MeSH Number(s) |
D03.633.100.759.160
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Allopurinol".
Below are MeSH descriptors whose meaning is more specific than "Allopurinol".
This graph shows the total number of publications written about "Allopurinol" by people in this website by year, and whether "Allopurinol" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2013 | 1 | 1 | 2 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Allopurinol" by people in Profiles.
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Significant erythroid megaloblastic changes in patients treated with allopurinol during maintenance chemotherapy for acute lymphoblastic leukemia. Pediatr Blood Cancer. 2023 11; 70(11):e30631.
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Allopurinol Initiation and All-Cause Mortality Among Patients With Gout and Concurrent Chronic Kidney Disease : A Population-Based Cohort Study. Ann Intern Med. 2022 04; 175(4):461-470.
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Comparative effectiveness of rasburicase versus allopurinol for cancer patients with renal dysfunction and hyperuricemia. Leuk Res. 2020 02; 89:106298.
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Use of allopurinol to reduce hepatotoxicity from 6-mercaptopurine (6-MP) in patients with acute lymphoblastic leukemia (ALL). Leuk Lymphoma. 2020 05; 61(5):1246-1249.
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50 Years Ago in The Journal of Pediatrics: Prevention and Management of Acute Hyperuricemia in Childhood Leukemia. J Pediatr. 2017 12; 191:178.
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Use of allopurinol in children with acute lymphoblastic leukemia to reduce skewed thiopurine metabolism. Pediatr Blood Cancer. 2014 Jun; 61(6):1114-7.
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3,4-Dihydroxy-5-nitrobenzaldehyde (DHNB) is a potent inhibitor of xanthine oxidase: a potential therapeutic agent for treatment of hyperuricemia and gout. Biochem Pharmacol. 2013 Nov 01; 86(9):1328-37.
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The status of allopurinol in the management of tumor lysis syndrome: a clinical review. Cancer J. 2005 Jan-Feb; 11 Suppl 1:S1-10.
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Expression of intercellular adhesion molecule-1 in the cortex of preserved rat kidneys. J Surg Res. 2001 Sep; 100(1):69-75.
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Normothermic renal artery perfusion: a comparison of perfusates. Ann Vasc Surg. 1996 Mar; 10(2):123-30.