"RNA-Binding Protein EWS" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitous hnRNP protein that contains an RNA RECOGNITION MOTIF and C-terminal ranBP2-type zinc finger. It localizes to the CELL NUCLEUS and CYTOPLASM and is expressed as different isoforms in various tissues, interacting with CALMODULIN and TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Translocations that result in the formation of fusion proteins containing parts of RNA-binding protein EWS are associated with EWING SARCOMA.
| Descriptor ID |
D034802
|
| MeSH Number(s) |
D12.644.360.650 D12.776.157.142.750 D12.776.157.725.813.750.900 D12.776.476.650 D12.776.624.664.700.913 D12.776.664.962.813.750.900
|
| Concept/Terms |
RNA-Binding Protein EWS- RNA-Binding Protein EWS
- EWS, RNA-Binding Protein
- RNA Binding Protein EWS
- EWSR1 Protein
- Protein, EWSR1
- Ewing Sarcoma Breakpoint Region 1 Protein
- EWS Proto-Oncogene Protein
- EWS Proto Oncogene Protein
- Proto-Oncogene Protein, EWS
- Ewing Sarcoma Breakpointregion 1 Protein
- EWS RNA Binding Protein 1
- EWS Protein
|
Below are MeSH descriptors whose meaning is more general than "RNA-Binding Protein EWS".
Below are MeSH descriptors whose meaning is more specific than "RNA-Binding Protein EWS".
This graph shows the total number of publications written about "RNA-Binding Protein EWS" by people in this website by year, and whether "RNA-Binding Protein EWS" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 2 | 2 |
| 2003 | 2 | 0 | 2 |
| 2005 | 0 | 3 | 3 |
| 2006 | 0 | 3 | 3 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 6 | 6 |
| 2009 | 0 | 4 | 4 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 3 | 3 |
| 2014 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 0 | 2 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 3 | 0 | 3 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 4 | 4 |
| 2024 | 0 | 3 | 3 |
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Below are the most recent publications written about "RNA-Binding Protein EWS" by people in Profiles.
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Open-Label, Multicenter, Phase I/II, First-in-Human Trial of TK216: A First-Generation EWS::FLI1 Fusion Protein Antagonist in Ewing Sarcoma. J Clin Oncol. 2024 Nov; 42(31):3725-3734.
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Superficial Neurocristic EWSR1::FLI1 Fusion Tumor: A Distinctive, Clinically Indolent, S100 Protein/SOX10-Positive Neoplasm. Mod Pathol. 2024 Aug; 37(8):100537.
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Updates on WHO classification for small round cell tumors: Ewing sarcoma vs. everything else. Hum Pathol. 2024 05; 147:101-113.
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Sarcomas Harboring EWSR1::PATZ1 Fusions: A Clinicopathologic Study of 17 Cases. Mod Pathol. 2024 Feb; 37(2):100400.
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Extraenteric Malignant Gastrointestinal Neuroectodermal Tumor-A Clinicopathologic and Molecular Genetic Study of 11 Cases. Mod Pathol. 2023 07; 36(7):100160.
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Targeted long-read sequencing of the Ewing sarcoma 6p25.1 susceptibility locus identifies germline-somatic interactions with EWSR1-FLI1 binding. Am J Hum Genet. 2023 03 02; 110(3):427-441.
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Modeling Ewing Sarcoma Lung Metastasis. Curr Protoc. 2023 Feb; 3(2):e670.
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EWSR1-PATZ1 Fusion Gene in Ependymoma: A Report of Two Adult Cases and Systematic Review of Literature. JCO Precis Oncol. 2022 12; 6:e2200312.
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Sclerosing Epithelioid Fibrosarcoma: A Distinct Sarcoma With Aggressive Features. Am J Surg Pathol. 2021 03 01; 45(3):317-328.
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EWSR1-SMAD3 rearranged fibroblastic tumor: Case series and review. J Cutan Pathol. 2021 Feb; 48(2):255-262.