Proto-Oncogene Proteins c-fos
"Proto-Oncogene Proteins c-fos" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cellular DNA-binding proteins encoded by the c-fos genes (GENES, FOS). They are involved in growth-related transcriptional control. c-fos combines with c-jun (PROTO-ONCOGENE PROTEINS C-JUN) to form a c-fos/c-jun heterodimer (TRANSCRIPTION FACTOR AP-1) that binds to the TRE (TPA-responsive element) in promoters of certain genes.
| Descriptor ID |
D016760
|
| MeSH Number(s) |
D12.776.260.108.765 D12.776.624.664.700.179 D12.776.660.760 D12.776.930.127.765
|
| Concept/Terms |
Proto-Oncogene Proteins c-fos- Proto-Oncogene Proteins c-fos
- Proto Oncogene Proteins c fos
- fos Proto-Oncogene Proteins
- fos Proto Oncogene Proteins
- Proto-Oncogene Proteins fos
- Proto Oncogene Proteins fos
- p55(c-fos)
- Proto-Oncogene Products c-fos
- Proto Oncogene Products c fos
- c-fos Proteins
- c fos Proteins
- p55 c-fos
- p55 c fos
|
Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-fos".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-fos".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-fos" by people in this website by year, and whether "Proto-Oncogene Proteins c-fos" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 1994 | 1 | 3 | 4 |
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 4 | 5 |
| 1997 | 2 | 3 | 5 |
| 1998 | 4 | 2 | 6 |
| 1999 | 1 | 1 | 2 |
| 2000 | 0 | 4 | 4 |
| 2001 | 0 | 3 | 3 |
| 2002 | 1 | 3 | 4 |
| 2003 | 1 | 2 | 3 |
| 2004 | 0 | 2 | 2 |
| 2005 | 2 | 2 | 4 |
| 2006 | 1 | 4 | 5 |
| 2007 | 6 | 0 | 6 |
| 2008 | 1 | 4 | 5 |
| 2009 | 1 | 2 | 3 |
| 2010 | 3 | 1 | 4 |
| 2011 | 1 | 3 | 4 |
| 2012 | 0 | 3 | 3 |
| 2013 | 1 | 2 | 3 |
| 2014 | 1 | 4 | 5 |
| 2015 | 0 | 2 | 2 |
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 2 | 3 |
| 2019 | 0 | 2 | 2 |
| 2020 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Proto-Oncogene Proteins c-fos" by people in Profiles.
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Persistent ?FosB expression limits recurrent seizure activity and provides neuroprotection in the dentate gyrus of APP mice. Prog Neurobiol. 2024 Jun; 237:102612.
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Long Noncoding RNA Fos Downstream Transcript Is Developmentally Dispensable but Vital for Shaping the Poststroke Functional Outcome. Stroke. 2021 07; 52(7):2381-2392.
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Regorafenib is effective against neuroblastoma in vitro and in vivo and inhibits the RAS/MAPK, PI3K/Akt/mTOR and Fos/Jun pathways. Br J Cancer. 2020 08; 123(4):568-579.
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Anticonvulsant action of a selective phosphatidylinositol-3-kinase inhibitor LY294002 in pentylenetetrazole-mediated convulsions in zebrafish. Epilepsy Res. 2019 11; 157:106207.
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Early a-linolenic acid exposure to embryo reduces pentylenetetrazol-induced seizures in zebrafish larva. Prostaglandins Leukot Essent Fatty Acids. 2019 04; 143:15-20.
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Inhibitor of Differentiation-1 Sustains Mutant KRAS-Driven Progression, Maintenance, and Metastasis of Lung Adenocarcinoma via Regulation of a FOSL1 Network. Cancer Res. 2019 02 01; 79(3):625-638.
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Dependence of c-fos Expression on Amplitude of High-Frequency Spinal Cord Stimulation in a Rodent Model. Neuromodulation. 2019 Feb; 22(2):172-178.
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The anti-epileptogenic and cognition enhancing effect of novel 1-[4-(4-benzo [1, 3] dioxol-5-ylmethyl-piperazin-1-yl)-phenyl]-3-phenyl-urea (BPPU) in pentylenetetrazole induced chronic rat model of epilepsy. Biomed Pharmacother. 2018 Sep; 105:470-480.
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Genome-wide profiling reveals functional diversification of ?FosB gene targets in the hippocampus of an Alzheimer's disease mouse model. PLoS One. 2018; 13(2):e0192508.
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Binge ethanol effects on prefrontal cortex neurons, spatial working memory and task-induced neuronal activation in male and female rats. Physiol Behav. 2018 05 01; 188:79-85.